Abstract: A medical appliance for the treatment of one or more sleep disorders such as obstructive sleep apnea in a patient, the appliance comprising: a biasing member for inserting behind and exerting a force upon the patient's soft palate or tongue, wherein the biasing member is inserted in a reduced or minimized form and then expanded or firms once in place to exert the force. The appliance may be nasally inserted or be placed through the mouth. In a particular configuration, both the soft palate and tongue are biased to prevent obstruction of the flow of air in the nasopharyngeal airway.

Abstract: An actuator for selectively moving a part relative to another part includes a shape memory wire, which contracts when heated. One portion of the shape memory wire is fixed to a first body, and another portion of the shape memory wire is coupled to a second body, which is movable relative to the first body. When heated the shape memory wire contracts and moves the second body in a direction of travel from a first position relative to the first body toward a second position. The actuator further includes a magnetic field for generating a magnetic force on the second body. The magnetic force acts on and moves the second body in the direction of travel to the second position after the shape memory wire initially contracts, and further decouples the second body from the shape memory wire when applying the magnetic force to the second body to thereby unload the load on the shape memory wire when the second body is moved to the second position.

Abstract: A system is disclosed that provides a goal based learning system utilizing a rule based expert training system to provide a cognitive educational experience. The system provides the user with a simulated environment that presents a business opportunity to understand and solve optimally. Mistakes are noted and remedial educational material presented dynamically to build the necessary skills that a user requires for success in the business endeavor. The system utilizes an artificial intelligence engine driving individualized and dynamic feedback with synchronized video and graphics used to simulate real-world environment and interactions. A robust business model provides support for realistic activities and allows a user to experience real world consequences for their actions and decisions and entails realtime decision-making and synthesis of the educational material. The system is architectured around a table of components to manage and control the system.

Abstract: A method of formulating a patient-specific plan for a diagnostic or therapeutic procedure performed upon a patient is provided. The method includes obtaining a standard plan based upon a scan of an anatomy of a standard anatomic specimen, the scan defining a standard scan. The method also includes scanning the patient to obtain a patient-specific scan of an anatomy of the patient. Additionally, the method includes morphing the standard scan to the anatomy of the patient by mapping the standard scan to the patient-specific scan. The method further includes determining the patient-specific plan by modifying the standard plan based upon the mapping.

Abstract: A system is disclosed that provides a goal based learning system utilizing a rule based expert training system to provide a cognitive educational experience. The system provides the user with a simulated environment that presents a business opportunity to understand and solve optimally. Mistakes are noted and remedial educational material presented dynamically to build the necessary skills that a user requires for success in the business endeavor. The system utilizes an artificial intelligence engine driving individualized and dynamic feedback with synchronized video and graphics used to simulate real-world environment and interactions. A robust business model provides support for realistic activities and allows a user to experience real world consequences for their actions and decisions and entails realtime decision-making and synthesis of the educational material. The system is architectured around a table of components to manage and control the system.

Abstract: A system is disclosed that provides a goal based learning system utilizing a rule based expert training system to provide a cognitive educational experience. The system provides the user with a simulated environment that presents a business opportunity to understand and solve optimally. Mistakes are noted and remedial educational material presented dynamically to build the necessary skills that a user requires for success in the business endeavor. The system utilizes an artificial intelligence engine driving individualized and dynamic feedback with synchronized video and graphics used to simulate real-world environment and interactions. A robust business model provides support for realistic activities and allows a user to experience real world consequences for their actions and decisions and entails realtime decision-making and synthesis of the educational material. The system is architectured around a table of components to manage and control the system.

Abstract: A system is disclosed that provides a goal based learning system utilizing a rule based expert training system to provide a cognitive educational experience. The system provides the user with a simulated environment that presents a business opportunity to understand and solve optimally. Mistakes are noted and remedial educational material presented dynamically to build the necessary skills that a user requires for success in the business endeavor. The system utilizes an artificial intelligence engine driving individualized and dynamic feedback with synchronized video and graphics used to simulate real-world environment and interactions. Multiple “correct” answers are integrated into the learning system to allow individualized learning experiences in which navigation through the system is at a pace controlled by the learner.

Abstract: An actuator for selectively moving a part relative to another part includes a shape memory wire, which contracts when heated. One portion of the shape memory wire is fixed to a first body, and another portion of the shape memory wire is coupled to a second body, which is movable relative to the first body. When heated the shape memory wire contracts and moves the second body in a direction of travel from a first position relative to the first body toward a second position. The actuator further includes a magnetic field for generating a magnetic force on the second body. The magnetic force acts on and moves the second body in the direction of travel to the second position after the shape memory wire initially contracts, and further decouples the second body from the shape memory wire when applying the magnetic force to the second body to thereby unload the load on the shape memory wire when the second body is moved to the second position.

Abstract: An actuator for selectively moving a part relative to another part includes a shape memory wire, which contracts upon heating, and a magnetic field. One end of the shape memory wire is fixed to a first body. The other end of the shape memory wire is coupled to a second body, which is movable relative to the first body. When heated, the shape memory wire contracts and moves the second body in a direction of travel from a first position relative to the first body toward a second position. A magnetic field generates a magnetic force on the second body, which acts on and moves the second body in the direction of travel to the second position after the shape memory wire initially contracts to thereby reduce the load on the shape memory wire when the second body is moved to the second position. The actuator may be used, for example, to move the valve stem in a valve.

Abstract: A method of formulating a patient-specific plan for a diagnostic or therapeutic procedure performed upon a patient is provided. The method includes obtaining a standard plan based upon a scan of an anatomy of a standard anatomic specimen, the scan defining a standard scan. The method also includes scanning the patient to obtain a patient-specific scan of an anatomy of the patient. Additionally, the method includes morphing the standard scan to the anatomy of the patient by mapping the standard scan to the patient-specific scan. The method further includes determining the patient-specific plan by modifying the standard plan based upon the mapping.

Abstract: An actuator for selectively moving a part relative to another part includes a shape memory wire, which contracts upon heating, and a magnetic field. One end of the shape memory wire is fixed to a first body. The other end of the shape memory wire is coupled to a second body, which is movable relative to the first body. When heated, the shape memory wire contracts and moves the second body in a direction of travel from a first position relative to the first body toward a second position. A magnetic field generates a magnetic force on the second body, which acts on and moves the second body in the direction of travel to the second position after the shape memory wire initially contracts to thereby reduce the load on the shape memory wire when the second body is moved to the second position. The actuator may be used, for example, to move the valve stem in a valve.

Abstract: A method of preplaining for guided medical procedures includes obtaining a first 3D diagnostic dataset for a region of interest of a subject. This first dataset can be a non-stereotactic dataset and provide sufficient contrast to identify target tissue in the region of interest. A treatment preplan is developed to treat the target tissue using the first dataset exclusive of stereotactic data. The treatment preplan includes placement locations for a plurality of initial radiation beams and their respective dose intensities. A second, stereotactic 3D dataset can be obtained for the region of interest. A registered dataset can then be created by registering the first dataset to the second dataset. The treatment preplan can be modified using data associated with the registering step to generate a stereotactic treatment plan including a plurality of radiation treatment beams with respective placement positions based on the registered dataset to treat the target tissue.

Abstract: Devices, methods and systems for frameless guidance of image-based medical procedures such as stereotactic radiotherapy and surgery. Devices including custom fitting subject-specific articles include contoured surfaces that provide spatial reference to the location of target regions within the subject. The devices are attached exclusive of fasteners anchored to the tissue of the subject and reside on the front of a head of the subject when attached. The devices and articles can be fabricated using computer-directed fabrication technology.

Abstract: Repeat fixation for medical procedures is accomplished using a non-invasive locator, specifically a face mask. The face mask has at least three fiducial markers on it. By detecting the position of the markers, the position of features within the patient can be determined with great precision. The features can be the location of head or neck cancer or other target to which radiation or other medical procedure is to be applied. Since the face mask has been molded to uniquely fit to the patient's face, it may be removed after an initial imaging of the patient. The face mask may then be re-attached one or more times to the teeth. The face mask is molded to conform to the patient's face by using thermoplastic material.

Abstract: Devices, methods and systems for frameless guidance of image-based medical procedures such as stereotactic radiotherapy and surgery. Devices including custom fitting subject-specific articles include contoured surfaces that provide spatial reference to the location of target regions within the subject. The devices and articles can be fabricated using computer-directed fabrication technology.

Abstract: A computer controlled system for guiding the needle device, such as a biopsy needle, by reference to a single mode medical imaging system employing any one of computed tomography imaging (CTI) equipment, magnetic resonance imaging equipment (MRI), fluoroscopic imaging equipment, or 3D ultrasound system, or alternatively, by reference to a multi-modal imaging system, which includes any combination of the aforementioned systems. The 3D ultrasound system includes a combination of an ultrasound probe and both passive and active infrared tracking systems so that the combined system enables a real time image display of the entire region of interest without probe movement.

Abstract: A system is disclosed that provides a goal based learning system utilizing a rule based expert training system to provide a cognitive educational experience. The system provides the user with a simulated environment that presents a business opportunity to understand and solve optimally. Mistakes are noted and remedial educational material presented dynamically to build the necessary skills that a user requires for success in the business endeavor. The system utilizes an artificial intelligence engine driving individualized and dynamic feedback with synchronized video and graphics used to simulate real-world environment and interactions. Multiple “correct” answers are integrated into the learning system to allow individualized learning experiences in which navigation through the system is at a pace controlled by the learner.

Abstract: A system comprising a combination of an ultrasound probe and both passive and active infrared tracking systems. The combined system enables a real time image display of the entire region of interest without probe movement; real time tracking of the target region permitting physiological gating; and probe placement during image acquisition so that all external displacements introduced by the probe can be accounted for at the time of treatment planning. This system may be used in the surgical arena for image guidance during radiation therapy and surgery.

Abstract: A system is disclosed that provides a goal based learning system utilizing a rule based expert training system to provide a cognitive educational experience. The system provides the user with a simulated environment that presents a business opportunity to understand and solve optimally. Mistakes are noted and remedial educational material presented dynamically to build the necessary skills that a user requires for success in the business endeavor. The system utilizes an artificial intelligence engine driving individualized and dynamic feedback with synchronized video and graphics used to simulate real-world environment and interactions. Multiple “correct” answers are integrated into the learning system to allow individualized learning experiences in which navigation through the system is at a pace controlled by the learner.

Abstract: Repeat fixation for medical procedures is accomplished using a non-invasive locator, specifically a bite plate. The bite plate has at least three fiducial markers on it. The fiducial markers may be LEDs, radiopaque markers for angiography or computerized tomography (CT) imaging or magnetic resonance markers for magnetic resonance (MR) imaging. By detecting the position of the markers, the position of features within the patient (such as a brain tumor or other intracranial target to which radiation is to be applied) can be determined with great precision. Since the bite plate has been molded to uniquely fit to the patient's teeth, it may be removed after an initial imaging of the patient. The bite plate may then be re-attached one or more times to the teeth. An alternate embodiment uses a head ring or head holder such as a head mask system with the LEDs thereon. The head ring is useful for single fraction treatments.