Patents by Inventor William A. Grady
William A. Grady has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).
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Patent number: 10211328Abstract: A normally-off, heterojunction field effect transistor includes an intrinsic cubic-phase gallium nitride (c-GaN) substrate and an aluminum gallium nitride (AlGaN) capping layer disposed on the intrinsic c-GaN substrate. The AlGaN capping layer includes a first sublayer of intrinsic c-phase AlxGa1-xN disposed on the c-GaN substrate, wherein the first sublayer is of a first thickness; a second sublayer of doped c-phase AlxGa1-xN disposed on the first sublayer, and wherein the second sublayer is of a second thickness and is doped with a dopant. An insulating layer is disposed on the AlGaN capping layer, wherein the insulating layer is of a fourth thickness. A source electrode, a drain electrode, and a gate electrode are positioned adjacent to and on top of the insulating layer, respectively.Type: GrantFiled: September 13, 2017Date of Patent: February 19, 2019Assignee: Board of Trustees of the University of IllinoisInventors: Can Bayram, Ryan William Grady, Kihoon Park
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Publication number: 20180083133Abstract: A normally-off, heterojunction field effect transistor includes an intrinsic cubic-phase gallium nitride (c-GaN) substrate and an aluminum gallium nitride (AlGaN) capping layer disposed on the intrinsic c-GaN substrate. The AlGaN capping layer includes a first sublayer of intrinsic c-phase AlxGa1-xN disposed on the c-GaN substrate, wherein the first sublayer is of a first thickness; a second sublayer of doped c-phase AlxGa1-xN disposed on the first sublayer, and wherein the second sublayer is of a second thickness and is doped with a dopant. An insulating layer is disposed on the AlGaN capping layer, wherein the insulating layer is of a fourth thickness. A source electrode, a drain electrode, and a gate electrode are positioned adjacent to and on top of the insulating layer, respectively.Type: ApplicationFiled: September 13, 2017Publication date: March 22, 2018Inventors: Can Bayram, Ryan William Grady, Kihoon Park
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Publication number: 20140206855Abstract: Methods are provided for detection of cancers associated with methylation of hMLH1 promoter DNA in a subject. The method comprise assaying for the presence of methylated hMLH1 promoter DNA in a bodily fluid from a subject. In one embodiment, the method comprises reacting DNA from the sample with a chemical compound that converts non-methylated cytosine bases but not methylated cytosine bases, to a different nucleotide base. The compound-converted DNA is then amplified using a methylation-sensitive polymerase chain reaction (MSP) employing primers that amplify the compound-converted DNA template. The present invention also provides nucleotide primer sequences for use in the methylation-sensitive PCR assay.Type: ApplicationFiled: January 16, 2014Publication date: July 24, 2014Applicant: CASE WESTERN RESERVE UNIVERSITYInventors: Sanford D. Markowitz, William Grady
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Patent number: 8695861Abstract: A stitching head is provided having a cam connected to the bender rail rail, the cam operates to redirect the staple driving force being applied by the driver rail to the driver and upon the staple during the staple driving step of stitching head operation; the force-redirecting position of the cam is automatically adjusted in response to the thickness of each workpiece as the cam is connected to the bender rail rail and the contacting of the workpiece by the bender rail repositions the cam at the desired distance above the workpiece to reestablish the set-point for the redirection of the staple driving force being applied to the driver rail upon as staple head contacts each variable thickness workpiece.Type: GrantFiled: August 17, 2011Date of Patent: April 15, 2014Inventor: William Grady Duff
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Patent number: 8669060Abstract: Methods are provided for detection of cancers associated with methylation of hMLH1 promoter DNA in a subject. The method comprise assaying for the presence of methylated hMLH1 promoter DNA in a bodily fluid from a subject. In one embodiment, the method comprises reacting DNA from the sample with a chemical compound that converts non-methylated cytosine bases but not methylated cytosine bases, to a different nucleotide base. The compound-converted DNA is then amplified using a methylation-sensitive polymerase chain reaction (MSP) employing primers that amplify the compound-converted DNA template. The present invention also provides nucleotide primer sequences for use in the methylation-sensitive PCR assay.Type: GrantFiled: January 5, 2005Date of Patent: March 11, 2014Assignee: Case Western Reserve UniversityInventors: Sanford Markowitz, William Grady
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Patent number: 8485425Abstract: Each respective mail item in a received batch of items is read to acquire information, which enables a plurality of verifications with regard to authenticity of the respective mail item. In a vote-by-mail example, one or more features are validated for authenticity in relation to the election, and one or more features are validated for authenticity in relation to a voter. The verifications in relation to a voter may involve detection of a signature and verification of the authenticity of the signature. The items are sorted according to the verification results and may be sorted based on other criteria. The methods, systems and software disclosed herein enable such verifications and sorting, in a single pass through a sorting system.Type: GrantFiled: January 22, 2007Date of Patent: July 16, 2013Assignee: Bell and Howell, LLCInventors: Christopher J. Kite, George Mavelil Varghese, Arkadiusz Nieckarz, William A. Grady, Michelle R. Archer
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Patent number: 8326898Abstract: The present application generally relates to address data maintenance services using a mail processing system. The present application discloses techniques and equipment to update address information and usage of mail processing equipment to print delivery point barcodes that represent the current and accurate address information available for the addressee. The present application also provides a new approach for storing and searching address and name run time directories as part of a mail processing system using address reader technology.Type: GrantFiled: May 14, 2009Date of Patent: December 4, 2012Assignee: Bell & Howell, LLCInventors: Mark Woolston, Walter S. Conard, William A. Grady, Brian Bowers, Richard Wojdyla, Gary Van Ermen
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Publication number: 20120043365Abstract: A stitching head is provided having a cam connected to the bender rail rail, the cam operates to redirect the staple driving force being applied by the driver rail to the driver and upon the staple during the staple driving step of stitching head operation; the force-redirecting position of the cam is automatically adjusted in response to the thickness of each workpiece as the cam is connected to the bender rail rail and the contacting of the workpiece by the bender rail repositions the cam at the desired distance above the workpiece to reestablish the set-point for the redirection of the staple driving force being applied to the driver rail upon as staple head contacts each variable thickness workpiece.Type: ApplicationFiled: August 17, 2011Publication date: February 23, 2012Inventor: William Grady Duff
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Publication number: 20090287742Abstract: The present application generally relates to address data maintenance services using a mail processing system. The present application discloses techniques and equipment to update address information and usage of mail processing equipment to print delivery point barcodes that represent the current and accurate address information available for the addressee. The present application also provides a new approach for storing and searching address and name run time directories as part of a mail processing system using address reader technology.Type: ApplicationFiled: May 14, 2009Publication date: November 19, 2009Inventors: Mark WOOLSTON, Walter S. Conard, William A. Grady, Brian Bowers, Richard Wojdyla, Gary Van Ermen
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Publication number: 20090227537Abstract: The invention provides sulfated oxidised regenerated cellulose compounds, sulfated alginates, and the salts and hydrates thereof. The compounds are obtained by sulfation of oxidised regenerated cellulose with sulfur trioxide. The invention also provides pharmaceutical compositions comprising the compounds, in particular compositions for the treatment of medical conditions mediated by a matrix metalloproteinases and anticoagulant pharmaceutical compositions.Type: ApplicationFiled: May 13, 2009Publication date: September 10, 2009Applicant: SYSTAGENIX WOUND MANAGEMENT (US), INC.Inventors: MICHAEL WILLIAM GRADY, Laura Sinclair, Paul Houston, Peter John Doyle
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Publication number: 20080173714Abstract: Each respective mail item in a received batch of items is read to acquire information, which enables a plurality of verifications with regard to authenticity of the respective mail item. In a vote-by-mail example, one or more features are validated for authenticity in relation to the election, and one or more features are validated for authenticity in relation to a voter. The verifications in relation to a voter may involve detection of a signature and verification of the authenticity of the signature. The items are sorted according to the verification results and may be sorted based on other criteria. The methods, systems and software disclosed herein enable such verifications and sorting, in a single pass through a sorting system.Type: ApplicationFiled: January 22, 2007Publication date: July 24, 2008Inventors: Christopher J. Kite, George Mavelil Varghese, Arkadiusz Nieckarz, William A. Grady, Michelle R. Archer
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Publication number: 20070185461Abstract: A medical device for use with a fluid transfer device includes a hub having an open proximal end with a frusto-conically-shaped cavity therein, a distal end and a passageway therethrough. The cavity is part of the passageway. A release element in the passageway of the hub is positioned to block fluid-tight engagement of the frusto-conically-shaped tip with the cavity of the hub. Structure is provided to release at least part of the release element, upon application of a proximally directed force on the hub, to allow the abrupt fluid-tight engagement of the tip and the cavity in the hub.Type: ApplicationFiled: January 4, 2007Publication date: August 9, 2007Applicant: BECTON, DICKINSON AND COMPANYInventors: Richard Caizza, William Grady
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Publication number: 20070173776Abstract: A medical device for use with a fluid transfer device includes a hub having an open proximal end with a frusto-conically-shaped cavity therein, a distal end and a passageway therethrough. The cavity is part of the passageway. A release element in the passageway of the hub is positioned to block fluid-tight engagement of the frusto-conically-shaped tip with the cavity of the hub. Structure is provided to release at least part of the release element, upon application of a proximally directed force on the hub, to allow the abrupt fluid-tight engagement of the tip and the cavity in the hub.Type: ApplicationFiled: January 4, 2007Publication date: July 26, 2007Applicant: BECTON, DICKINSON AND COMPANYInventors: RICHARD CAIZZA, William Grady
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Publication number: 20050153351Abstract: Methods are provided for detection of cancers associated with methylation of hMLH1 promoter DNA in a subject. The method comprise assaying for the presence of methylated hMLH1 promoter DNA in a bodily fluid from a subject. In one embodiment, the method comprises reacting DNA from the sample with a chemical compound that converts non-methylated cytosine bases but not methylated cytosine bases, to a different nucleotide base. The compound-converted DNA is then amplified using a methylation-sensitive polymerase chain reaction (MSP) employing primers that amplify the compound-converted DNA template. The present invention also provides nucleotide primer sequences for use in the methylation-sensitive PCR assay.Type: ApplicationFiled: January 5, 2005Publication date: July 14, 2005Inventors: Sanford Markowitz, William Grady
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Patent number: 6858388Abstract: Methods are provided for detection of cancers associated with methylation of hMLH1 promoter DNA in a subject. The method comprise assaying for the presence of methylated hMLH1 promoter DNA in a bodily fluid from a subject. In one embodiment, the method comprises reacting DNA from the sample with a chemical compound that converts non-methylated cytosine bases but not methylated cytosine bases, to a different nucleotide base. The compound-converted DNA is then amplified using a methylation-sensitive polymerase chain reaction (MSP) employing primers that amplify the compound-converted DNA template. The present invention also provides nucleotide primer sequences for use in the methylation-sensitive PCR assay.Type: GrantFiled: September 20, 2001Date of Patent: February 22, 2005Assignee: Case Western Reserve UniversityInventors: Sanford Markowitz, William Grady
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Publication number: 20030068620Abstract: Methods are provided for detection of cancers associated with methylation of hMLH1 promoter DNA in a subject. The method comprise assaying for the presence of methylated hMLH1 promoter DNA in a bodily fluid from a subject. In one embodiment, the method comprises reacting DNA from the sample with a chemical compound that converts non-methylated cytosine bases but not methylated cytosine bases, to a different nucleotide base. The compound-converted DNA is then amplified using a methylation-sensitive polymerase chain reaction (MSP) employing primers that amplify the compound-converted DNA template. The present invention also provides nucleotide primer sequences for use in the methylation-sensitive PCR assay.Type: ApplicationFiled: September 20, 2001Publication date: April 10, 2003Inventors: Sanford Markowitz, William Grady