Abstract: A detection system includes a first sensor coupled to a pipe associated with a pump and generates temperature data associated with a temperature of the pipe. The system includes a second sensor positioned within an acoustic sensing distance from the pump and that generates sound data associated with a sound of the pump. The system includes a processing device configured to execute data instructions to store a baseline temperature signature and a baseline acoustic signature, and receive the temperature data from the first sensor and the sound data from the second sensor. The processing device is configured to, based on (1) a determination that flow through the pipe is reduced by comparing temperature data to the baseline temperature signature, and (2) a determination that the pump remains operational based on comparing the acoustic data to the baseline acoustic signature, generate an indication that the pipe is blocked.

Abstract: The present invention relates to biomarker signatures and associated methods for identifying patients that are not likely to manifest significant coronary artery disease. It is based, at least in part, on a study performed on serum samples of 239 patients with clinical symptoms of cardiac distress, some of whom required invasive intervention (stent placement or bypass graft surgery). A set of biomarkers was identified as exhibiting different levels of expression in subjects that did, or did not, require invasive intervention. Further, an algorithm was developed which, using serum levels of these biomarkers, assigned a score to a given patient that was indicative of whether that patient required invasive intervention.

Abstract: A detection system and method of operation are disclosed. The system includes a first sensor coupled to a pipe associated with a pump and generates temperature data associated with a temperature of the pipe. The system includes a second sensor positioned within an acoustic sensing distance from the pump and that generates sound data associated with a sound of the pump. The system includes a processing device configured to execute data instructions to store a baseline temperature signature and a baseline acoustic signature, and receive the temperature data from the first sensor and the sound data from the second sensor. The processing device is configured to, based on (1) a determination that flow through the pipe is reduced by comparing temperature data to the baseline temperature signature, and (2) a determination that the pump remains operational based on comparing the acoustic data to the baseline acoustic signature, generate an indication that the pipe is blocked.

Abstract: The present invention relates to biomarker signatures and associated methods for identifying patients that are not likely to manifest significant coronary artery disease. It is based, at least in part, on a study performed on serum samples of 239 patients with clinical symptoms of cardiac distress, some of whom required invasive intervention (stent placement or bypass graft surgery). A set of biomarkers was identified as exhibiting different levels of expression in subjects that did, or did not, require invasive intervention. Further, an algorithm was developed which, using serum levels of these biomarkers, assigned a score to a given patient that was indicative of whether that patient required invasive intervention.