Patents by Inventor William A. LaMarr

William A. LaMarr has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Systems and methods for high-throughput screening of fluidic samples
    Patent number: 8414774
    Abstract: Aspects of the invention provide systems and methods for high-throughput screening of fluidic samples. In some embodiments, two chromatography columns are utilized in series. The first chromatography column can have a high affinity for phosphorylated compounds while the second chromatography column has a high affinity for one or more analytes of interest.
    Type: Grant
    Filed: September 15, 2009
    Date of Patent: April 9, 2013
    Assignee: Agilent Technologies, Inc.
    Inventors: William A. LaMarr, Can C. Ozbal, Arrin Katz, Donald Green
  • Devices and methods for coupling mass spectrometry devices with chromatography systems
    Patent number: 8410426
    Abstract: One embodiment of the invention provides a method of preparing an eluted sample containing salts or buffers from a liquid chromatography device for analysis by a mass spectrometry device. The method includes: continuously providing a non-polar solvent to the mass spectrometry device; receiving the eluted sample from the liquid chromatography device; flowing the eluted sample over a solid phase extraction column; flowing the non-polar solvent over the solid phase extraction column; and presenting non-polar solvent and the eluted sample to the mass spectrometry device.
    Type: Grant
    Filed: November 3, 2008
    Date of Patent: April 2, 2013
    Assignee: Agilent Technologies, Inc.
    Inventors: Can C. Ozbal, Maxine Jonas, William A. LaMarr, Eduard Vernikov
  • COMPOSITIONS AND METHODS FOR DETECTING DEACETYLASE ACTIVITY
    Publication number: 20110251104
    Abstract: A method for the quantitative determination of the activity of enzymes in the Sirtuin family through the quantification of the acetyl-ADPr product that is formed is provided. The method described allows for a wide range of substrates, including peptides, intact proteins, or protein complexes (e.g. nucleosomes) to be used as substrates without the need for additional analytical methods to be developed.
    Type: Application
    Filed: April 7, 2011
    Publication date: October 13, 2011
    Inventors: Can Ozbal, William LaMarr
  • DEVICES AND METHODS FOR COUPLING MASS SPECTROMETRY DEVICES WITH CHROMATOGRAPHY SYSTEMS
    Publication number: 20100237235
    Abstract: One embodiment of the invention provides a method of preparing an eluted sample containing salts or buffers from a liquid chromatography device for analysis by a mass spectrometry device. The method includes: continuously providing a non-polar solvent to the mass spectrometry device; receiving the eluted sample from the liquid chromatography device; flowing the eluted sample over a solid phase extraction column; flowing the non-polar solvent over the solid phase extraction column; and presenting non-polar solvent and the eluted sample to the mass spectrometry device.
    Type: Application
    Filed: November 3, 2008
    Publication date: September 23, 2010
    Applicant: Biocius Life Sceinces, Inc.
    Inventors: Can C. Ozbal, Maxine Jonas, William A. lamarr, Eduard Vernikov
  • SYSTEMS AND METHODS FOR HIGH-THROUGHPUT SCREENING OF FLUIDIC SAMPLES
    Publication number: 20100024527
    Abstract: Aspects of the invention provide systems and methods for high-throughput screening of fluidic samples. In some embodiments, two chromatography columns are utilized in series. The first chromatography column can have a high affinity for phosphorylated compounds while the second chromatography column has a high affinity for one or more analytes of interest.
    Type: Application
    Filed: September 15, 2009
    Publication date: February 4, 2010
    Applicant: BIOTROVE, INC.
    Inventors: William A. LaMarr, Can C. Ozbal, Arrin Katz, Donald Green