Patents by Inventor William A. Larson

William A. Larson has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Publication number: 20240132939
    Abstract: The invention generally relates to droplet based digital PCR and methods for analyzing a target nucleic acid using the same. In certain embodiments, methods of the invention involve forming sample droplets containing, on average, a single target nucleic acid, amplifying the target in the droplets, excluding droplets containing amplicon from the target and amplicon from a variant of the target, and analyzing target amplicons.
    Type: Application
    Filed: December 12, 2023
    Publication date: April 25, 2024
    Inventors: Jonathan William Larson, Qun Zhong, Darren Roy Link
  • Publication number: 20240093271
    Abstract: The invention generally relates to droplet based digital PCR and methods for analyzing a target nucleic acid using the same. In certain embodiments, methods of the invention involve forming sample droplets containing, on average, a single target nucleic acid, amplifying the target in the droplets, excluding droplets containing amplicon from the target and amplicon from a variant of the target, and analyzing target amplicons.
    Type: Application
    Filed: November 20, 2023
    Publication date: March 21, 2024
    Inventors: Jonathan William Larson, Qun Zhong, Darren Roy Link
  • Publication number: 20240002910
    Abstract: The invention generally relates to droplet based digital PCR and methods for analyzing a target nucleic acid using the same. In certain embodiments, methods of the invention involve forming sample droplets containing, on average, a single target nucleic acid, amplifying the target in the droplets, excluding droplets containing amplicon from the target and amplicon from a variant of the target, and analyzing target amplicons.
    Type: Application
    Filed: September 12, 2023
    Publication date: January 4, 2024
    Inventors: Jonathan William Larson, Qun Zhong, Darren Roy Link
  • Patent number: 11824497
    Abstract: A steady-state microwave conductivity method whereby a light beam is modulated to form an amplitude modulated light having a modulation frequency ?1. The method further includes producing a microwave waveform, exposing a sample to the amplitude modulated light and a first portion of the microwave waveform to produce an amplitude modulation signal on the first portion of the microwave waveform, and mixing a second portion of the microwave waveform and the amplitude modulation signal to produce a first signal and a second signal.
    Type: Grant
    Filed: November 4, 2022
    Date of Patent: November 21, 2023
    Assignees: Alliance for Sustainable Energy, LLC, The Regents of the University of Colorado
    Inventors: Bryon William Larson, Obadiah G. Reid
  • Publication number: 20230086845
    Abstract: The invention generally relates to droplet based digital PCR and methods for analyzing a target nucleic acid using the same. In certain embodiments, methods of the invention involve forming sample droplets containing, on average, a single target nucleic acid, amplifying the target in the droplets, excluding droplets containing amplicon from the target and amplicon from a variant of the target, and analyzing target amplicons.
    Type: Application
    Filed: November 22, 2022
    Publication date: March 23, 2023
    Inventors: Jonathan William Larson, Qun Zhong, Darren Roy Link
  • Publication number: 20230070273
    Abstract: The present disclosure relates to a steady-state microwave conductivity method that includes modulating a light beam to form an amplitude modulated light having a modulation frequency ?1, producing a microwave waveform, exposing a sample to the amplitude modulated light and a first portion of the microwave waveform to produce an amplitude modulation signal on the first portion of the microwave waveform, and mixing a second portion of the microwave waveform and the amplitude modulation signal to produce a first signal and a second signal.
    Type: Application
    Filed: November 4, 2022
    Publication date: March 9, 2023
    Inventors: Bryon William LARSON, Obadiah G. REID
  • Patent number: 11563405
    Abstract: The present disclosure relates to a steady-state microwave conductivity method that includes modulating a light beam to form an amplitude modulated light having a modulation frequency ?1, producing a microwave waveform, exposing a sample to the amplitude modulated light and a first portion of the microwave waveform to produce an amplitude modulation signal on the first portion of the microwave waveform, and mixing a second portion of the microwave waveform and the amplitude modulation signal to produce a first signal and a second signal.
    Type: Grant
    Filed: April 30, 2019
    Date of Patent: January 24, 2023
    Assignees: Alliance for Sustainable Energy, LLC, The Regents of the University of Colorado, a Body Corporate
    Inventors: Bryon William Larson, Obadiah G. Reid
  • Publication number: 20220213530
    Abstract: The invention generally relates to droplet based digital PCR and methods for analyzing a target nucleic acid using the same. In certain embodiments, methods of the invention involve forming sample droplets containing, on average, a single target nucleic acid, amplifying the target in the droplets, excluding droplets containing amplicon from the target and amplicon from a variant of the target, and analyzing target amplicons.
    Type: Application
    Filed: January 13, 2022
    Publication date: July 7, 2022
    Inventors: Jonathan William Larson, Qun Zhong, Darren Roy Link
  • Publication number: 20220143617
    Abstract: The invention provides methods for assessing one or more predetermined characteristics or properties of a microfluidic droplet within a microfluidic channel, and regulating one or more fluid flow rates within that channel to selectively alter the predetermined microdroplet characteristic or property using a feedback control.
    Type: Application
    Filed: January 24, 2022
    Publication date: May 12, 2022
    Inventors: Benjamin Miller, Brian Hutchison, Andrew Wilson, Jonathan William Larson, Qun Zhong, Yevgeny Yurkovetsky, Darren Link, Mark Weary
  • Publication number: 20220119716
    Abstract: A cracking furnace for cracking a hydrocarbon feed, the furnace including a firebox having a single radiant zone including, a first plurality of cracking coils each having a first shape arranged within the firebox. The radiant zone includes a second plurality of cracking coils each having a second shape arranged within the radiant zone. A burner section positioned below the first plurality cracking coils and below the second plurality of cracking coils. A convection section is positioned on top of the firebox configured to recover residual heat from the firebox.
    Type: Application
    Filed: October 15, 2020
    Publication date: April 21, 2022
    Applicant: Technip Process Technology, Inc.
    Inventors: Thomas M. Pickett, Yong Wang, Chinh Dang, William Larson, John Murphey, III, George Dabney, JR., Huynh Pham, Astrid Han
  • Patent number: 11268887
    Abstract: The invention provides methods for assessing one or more predetermined characteristics or properties of a microfluidic droplet within a microfluidic channel, and regulating one or more fluid flow rates within that channel to selectively alter the predetermined microdroplet characteristic or property using a feedback control.
    Type: Grant
    Filed: January 2, 2020
    Date of Patent: March 8, 2022
    Assignee: Bio-Rad Laboratories, Inc.
    Inventors: Benjamin Miller, Brian Hutchison, Andrew Wilson, Jonathan William Larson, Qun Zhong, Yevgeny Yurkovetsky, Darren Roy Link, Mark Weary
  • Patent number: 11254968
    Abstract: The invention generally relates to droplet based digital PCR and methods for analyzing a target nucleic acid using the same. In certain embodiments, methods of the invention involve forming sample droplets containing, on average, a single target nucleic acid, amplifying the target in the droplets, excluding droplets containing amplicon from the target and amplicon from a variant of the target, and analyzing target amplicons.
    Type: Grant
    Filed: August 28, 2017
    Date of Patent: February 22, 2022
    Assignee: Bio-Rad Laboratories, Inc.
    Inventors: Jonathan William Larson, Qun Zhong, Darren Roy Link
  • Patent number: 11077415
    Abstract: The invention generally relates to methods for forming mixed droplets. In certain embodiments, methods of the invention involve forming a droplet, and contacting the droplet with a fluid stream, wherein a portion of the fluid stream integrates with the droplet to form a mixed droplet.
    Type: Grant
    Filed: November 5, 2018
    Date of Patent: August 3, 2021
    Assignee: Bio-Rad Laboratories, Inc.
    Inventors: Yevgeny Yurkovetsky, Darren Roy Link, Jonathan William Larson
  • Publication number: 20210126581
    Abstract: The present disclosure relates to a steady-state microwave conductivity method that includes modulating a light beam to form an amplitude modulated light having a modulation frequency ?1, producing a microwave waveform, exposing a sample to the amplitude modulated light and a first portion of the microwave waveform to produce an amplitude modulation signal on the first portion of the microwave waveform, and mixing a second portion of the microwave waveform and the amplitude modulation signal to produce a first signal and a second signal.
    Type: Application
    Filed: April 30, 2019
    Publication date: April 29, 2021
    Inventors: Bryon William LARSON, Obadiah G. REID
  • Publication number: 20200410594
    Abstract: A system and computer-implemented method for use in generating an investment strategy for retirement income growth utilizing a total cost of ownership (TCO) obligation for an item as an input is provided. Information about the user may be gathered. An item having a TCO obligation may be determined using the user information. The TCO obligation for the item may be estimated from a plurality of sources. A category for the item may be determined. An impact on the user's retirement income growth based on the TCO obligation for the item may be assessed. A modification to the investment strategy, the item, and/or a lifestyle interest of the user may be recommended based on the assessed retirement income growth impact and/or the category of the item. Steps to implement the recommendation may then be provided to the user.
    Type: Application
    Filed: May 19, 2016
    Publication date: December 31, 2020
    Inventors: August William Larson, III, Donna E. Peterson, Christopher C. Maurer, Alexandra Rapp, Scarlette A. Rose, Dinah Villar, Barbara Ellen Metkowski, Michael Smid
  • Publication number: 20200225129
    Abstract: The invention provides methods for assessing one or more predetermined characteristics or properties of a microfluidic droplet within a microfluidic channel, and regulating one or more fluid flow rates within that channel to selectively alter the predetermined microdroplet characteristic or property using a feedback control.
    Type: Application
    Filed: January 2, 2020
    Publication date: July 16, 2020
    Inventors: Benjamin Miller, Brian Hutchison, Andrew Wilson, Jonathan William Larson, Qun Zhong, Yevgeny Yurkovetsky, Darren Roy Link, Mark Weary
  • Patent number: 10527529
    Abstract: The invention provides methods for assessing one or more predetermined characteristics or properties of a microfluidic droplet within a microfluidic channel, and regulating one or more fluid flow rates within that channel to selectively alter the predetermined microdroplet characteristic or property using a feedback control.
    Type: Grant
    Filed: August 10, 2017
    Date of Patent: January 7, 2020
    Assignee: Bio-Rad Laboratories, Inc.
    Inventors: Benjamin J. Miller, Brian Hutchison, Andrew Wilson, Jonathan William Larson, Qun Zhong, Yevgeny Yurkovetsky, Darren Roy Link, Mark Weary
  • Publication number: 20190351213
    Abstract: An example patient line dislodgement detection device includes a body having a plurality of openings. The plurality of openings are each configured to receive a tubing line therethrough. The device is configured such that a force applied to a tubing line causes the body to restrict fluid flow through the tubing line. During use, the tubing line is received through the body of the dislodgement device. Fluid flow is restricted by the dislodgement device through the tubing line in response to application of a force on the tubing line. A dislodgement condition can be detected based on restricting the fluid flow through the tubing line.
    Type: Application
    Filed: July 31, 2019
    Publication date: November 21, 2019
    Inventor: Byron William Larson
  • Patent number: 10398857
    Abstract: A patient line dislodgement detection device and method. An example device includes a body having an entrance and an exit. The entrance and the exit are each configured to receive a tubing line therethrough. Applying a force to a tubing line causes the body to restrict fluid flow through the tubing line, thereby indicating a dislodgement condition. An example method includes receiving a tubing line through a dislodgement device. The method also includes restricting fluid flow by the dislodgment device through the tubing line in response to application of a force on the tubing line. The method also includes detecting a dislodgment condition based on restricting the fluid flow through the tubing line.
    Type: Grant
    Filed: May 10, 2016
    Date of Patent: September 3, 2019
    Assignee: Toltec Ventures, LLC
    Inventor: Byron William Larson
  • Publication number: 20190134581
    Abstract: The invention generally relates to methods for forming mixed droplets. In certain embodiments, methods of the invention involve forming a droplet, and contacting the droplet with a fluid stream, wherein a portion of the fluid stream integrates with the droplet to form a mixed droplet.
    Type: Application
    Filed: November 5, 2018
    Publication date: May 9, 2019
    Inventors: Yevgeny Yurkovetsky, Darren Roy Link, Jonathan William Larson