Abstract: Provided herein are methods and compositions for treating von Willebrand disease with platelets, platelet derivatives, and/or thrombosomes.

Abstract: A cylinder sensor assembly, a system, and a method of operating a piston-cylinder assembly. The sensor assembly may generally include a housing; a sensor supported by the housing and configured to sense a position of a piston relative to a cylinder; and a wireless transmitter supported by the housing and configured to output a communication signal representative of a sensed position of the piston.

Abstract: Various implementations include a seat riser system. The system includes a base and a seat. The base has a base center line, a first base end, a second base end spaced apart along the base center line, a first base side, and a second base side spaced apart from the first base side. The seat has a seat center line, a first seat end, a second seat end spaced apart along the seat center line, a first seat side, a second seat side spaced apart from the first seat side, and a bottom seat surface rotationally coupled to the base such that the seat is rotatable about a seat rotational axis. The seat rotational axis is spaced apart from the seat center line such that the seat rotational axis is closer to the first seat side than it is to the second seat side.

Abstract: Techniques, which may be embodied herein as systems, computing devices, methods, algorithms, software, code, computer readable media, or the like, are described herein for comparing a set of metrics generated during a simulated user interaction with a website to metrics generated by observing real user interactions with the website. Simulated user interactions with a website can be used to diagnose a website's performance issues, but it can be difficult to determine whether the simulated interactions reflect the experience of real users. In addition, the simulated user interactions can be challenging to contextualize because the number of observed real user interactions may significantly outnumber the simulated interactions. A graphical user interface can help with the interpretation of these website interactions by using the real user interactions to properly contextualize the simulated results.

Abstract: Provided herein are methods for administering platelet derivatives, such as freeze-dried platelet derivatives (FDPDs) to a subject having Hermansky Pudlak Syndrome (HPS) or Bernard Soulier Syndrome (BSS), comprising administering an effective dose of the platelet derivatives in a platelet derivative composition to the subject. The platelet derivatives can have numerous characteristics provided herein, that make them well suited to restore hemostatic functions in the subject. In some embodiments, the platelet derivatives are from a pool of donors. Furthermore, provided herein are platelet derivatives, and methods using the same, that have numerous beneficial properties, as provided.

Abstract: An audio infusion system and method are disclosed. A source audio track is separated into a plurality of audio tracks (e.g., instrumental, vocal, or mixes thereof) and the audio tracks are individually processed to generate a plurality of binaural beat tracks. At least one spatialized track is also generated by filtering the source audio track to provide a filtered track, generating one or more spatialization trajectories based on certain audio feature(s) of the source audio track (e.g., tempo) and a target end-state effect, and spatializing the filtered track using the spatialization trajectories. Other tracks may also be generated, such as one or more infrasonic tracks, ultrasonic tracks, enhanced bass tracks, and/or subharmonic tracks. The tracks may be played simultaneously or mixed for delivery to an end user device.

Abstract: An anchor trajectory guide and methods of use thereof are provided. The guide includes a body that has a medial side. The medial side can be placed over a lateral side of a fixation plate. The anchor trajectory guide also includes a locator and a plurality of guide apertures. The locator is disposed on or through the medial side of the body. The locator can be mated with the fixation plate. The guide apertures are disposed through the body at positions corresponding to define anchor locations and orientations to provide good purchase adjacent to or in cortical bone around a medial side of a humerus.

Abstract: Provided is a glenoid implant for a shoulder prosthesis that includes: a baseplate including a proximal end, a distal end, an outer periphery, and one or more recesses that extend therethrough adjacent to the outer periphery and extending from the proximal end to the distal end; an internal member disposed in each of the one or more recesses, the internal member defining an aperture extending from the proximal end to the distal end through the internal member; and a screw for each of the at least one internal member, the screw configured to be placed through the aperture, the screw having an external threaded surface. The internal threaded surface of the internal member has more thread starts than the external threaded surface of the screw.

Abstract: In some embodiments provided herein is a method of treating a coagulopathy in a subject, the method including administering to the subject in need thereof an effective amount of a composition including platelets or platelet derivatives and an incubating agent including one or more salts, a buffer, optionally a cryoprotectant, and optionally an organic solvent, wherein the subject has been treated or is being treated with an antiplatelet agent.

Abstract: Techniques, which may be embodied herein as systems, computing devices, methods, algorithms, software, code, computer readable media, or the like, are described herein for comparing a set of metrics generated during a simulated user interaction with a website to metrics generated by observing real user interactions with the website. Simulated user interactions with a website can be used to diagnose a website's performance issues, but it can be difficult to determine whether the simulated interactions reflect the experience of real users. In addition, the simulated user interactions can be challenging to contextualize because the number of observed real user interactions may significantly outnumber the simulated interactions. A graphical user interface can help with the interpretation of these website interactions by using the real user interactions to properly contextualize the simulated results.

Abstract: In an embodiment, a device comprises a solar panel configured to harvest power from energy emitted as light by an indoor light source, a camera, and a processor coupled to the solar panel and the camera. The processor can be configured to: receive at least some of the power harvested by the solar panel, capture an image via the camera, and transmit the image to a computing device. A battery can be coupled to the solar panel and the processor that can be configured to store at least some of the power harvested by the solar panel and provide at least some of the stored power to the processor.

Abstract: Provided herein are methods and compositions for treating a coagulopathy in a subject. Such methods can include administering to the subject in need thereof, for example because they have been administered an anticoagulant agent, an effective amount of a composition including platelets, or in illustrative embodiments platelet derivatives, and in further illustrative embodiments freeze-dried platelet derivatives (FDPDs). Various properties of exemplary embodiments of such methods and platelet derivatives used therein, as well as numerous additional aspects and embodiments are provided herein.

Abstract: An audio infusion system and method are disclosed. A source audio track is separated into a plurality of audio tracks (e.g., instrumental, vocal, or mixes thereof) and the audio tracks are individually processed to generate a plurality of binaural beat tracks. At least one spatialized track is also generated by filtering the source audio track to provide a filtered track, generating one or more spatialization trajectories based on certain audio feature(s) of the source audio track (e.g., tempo) and a target end-state effect, and spatializing the filtered track using the spatialization trajectories. Other tracks may also be generated, such as one or more infrasonic tracks, ultrasonic tracks, enhanced bass tracks, and/or subharmonic tracks. The tracks may be played simultaneously or mixed for delivery to an end user device.

Abstract: Provided is a glenoid implant for a shoulder prosthesis that includes: a baseplate including a proximal end, a distal end, an outer periphery, and one or more recesses that extend therethrough adjacent to the outer periphery and extending from the proximal end to the distal end; an internal member disposed in each of the one or more recesses, the internal member defining an aperture extending from the proximal end to the distal end through the internal member; and a screw for each of the at least one internal member, the screw configured to be placed through the aperture, the screw having an external threaded surface. The internal threaded surface of the internal member has more thread starts than the external threaded surface of the screw.

Abstract: Provided is a slot anchor guide that includes a medial portion and a lateral portion, the medial portion includes a medial projection configured to span a slot of a fixation plate, where the slot anchor guide is configured to guide an anchor through a predetermined position of a slot of the fixation plate and to mate with the fixation plate to allow a surgeon to place the fixation plate on a bone face by manipulating the lateral portion. Also provided is a tuberosity fracture plate that includes a tuberosity end having a first portion configured to overlay a first tuberosity and a second portion opposite the first portion, a distal portion coupled with and extending away from the tuberosity portion.

Abstract: A method for identifying and indicating resource access faults associated with a webpage. The method includes receiving a machine-readable file that includes a plurality of instructions defining at least content and structure of a webpage. The method further comprises causing a browser to load the webpage based at least in part on the machine-readable file; determining resource utilization associated with the load of the webpage; identifying one or more resource access faults associated with the machine-readable file based at least in part on the determined resource utilization and a resource access instruction policy; for each of the one or more resource access faults, identifying an instruction of the plurality of instructions that corresponds to the particular resource access fault; and causing display of the one or more instructions.

Abstract: Various implementations include a clamping storage device. The device includes a clamping assembly having a proximal stop, a gas spring, and a distal stop. The proximal stop extends along a proximal stop longitudinal axis. The gas spring has a gas spring longitudinal axis, first end, and a second end. The first end of the gas spring is coupled to the proximal stop. The distal stop is coupled to the second end of the gas spring and extends along a distal stop longitudinal axis. The proximal stop longitudinal axis and the distal stop longitudinal axis are both locatable in an assembly plane that incudes the gas spring longitudinal axis. The gas spring is biased toward an extended position and urgable toward a retracted state. The gas spring is movable toward the extended position in an unlocked state and is prevented from being moved toward the extended position in a locked state.

Abstract: Provided herein are methods for administering platelet derivatives, such as freeze-dried platelet derivatives (FDPDs) to a subject, comprising administering an effective dose of the platelet derivatives in a platelet derivative composition to the subject. Such effective dose in illustrative embodiments, includes multiple individual doses, or a continuous dose administered within a time period, for example a time period of less than 4 hours. In certain aspects herein the subject is a subject having Hermansky Pudlak Syndrome (HPS). The platelet derivatives can have numerous characteristics provided herein that make them well suited to restore hemostatic functions in the subject. In some embodiments, the platelet derivatives are from a pool of donors, and are HLA Class 1-characterized platelet derivatives (e.g., FDPDs), which in certain illustrative embodiments are HLA Class 1-matched FDPDs.

Abstract: An interoperable power distribution apparatus and systems includes N power distribution base units having a first configuration as sequentially arranged along a first dimension and secured as removably attached, and a second configuration where each of the N power distribution base units are independently and removably attached to a surface of one of N welding machine support units having various first, second, or third orthogonal dimensions, the N power distribution base units interoperable between the N welding machine support units having varied first, second, or orthogonal third dimensions, wherein N is a positive natural number between 1 and 100.