Patents by Inventor William A. Million

William A. Million has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Intermediates for aminoglycoside antibiotics
    Patent number: 4160082
    Abstract: Derivatives of kanamycin A, which have an acyl protecting group on the C-3" and C-6' amino groups, and optionally have a benzyl protecting group on the C-3 amino group, are useful intermediates for the preparation of 1-N-(.omega.-amino-2-hydroxyalkyl) derivatives of kanamycin A. Derivatives of kanamycin B, which have an acyl protecting group on the C-2', C-3" and C-6' amino groups, and optionally have a benzyl protecting group on the C-3 amino group, are useful intermediates for the preparation of 1-N-(.omega.-amino-2-hydroxyalkyl) derivatives of kanamycin B. Certain of the partially protected kanamycin A and kanamycin B derivatives of this invention are useful for preparing 1-N-(.omega.-amino-2-hydroxyalkanoyl) derivatives of kanamycin A and B. 1-N-(.omega.-Amino-2-hydroxyalkyl) and 1-N-(.omega.-amino-2-hydroxyalkanoyl)derivatives of kanamycin A and B are known antibacterial agents.
    Type: Grant
    Filed: November 14, 1977
    Date of Patent: July 3, 1979
    Assignee: Pfizer Inc.
    Inventors: William A. Million, Rhona M. Plews, Kenneth Richardson