Abstract: A patient interface assembly has a patient interface and a securement system for the patient interface and/or patient interface tubing. The patient interface has a body and at least one nasal prong extending from the body. The at least one nasal prong has a gas inlet for fluid communication with a supply of breathable gas, and a gas outlet configured to direct a flow of gas towards a nare of the user's nose. The at least one nasal prong further includes an exterior surface, at least a portion of the exterior surface is a sealing surface configured to seal the nare of the user's nose. The securement system has a two-part releasable attachment or connection arrangement, the arrangement comprising a first patch and a second patch.

Abstract: A breathing circuit for use in respiratory therapy includes an inspiratory tube and an expiratory tube. The inspiratory tube of the breathing circuit has a smooth bore. The expiratory tube of the breathing circuit is corrugated. Preferably, the expiratory tube is vapor permeable. Using the combination of a smooth bore inspiratory tube with a corrugated expiratory tube has the unexpected result of improving the performance of the breathing circuit and its components.

Abstract: A patient interface assembly has a patient interface and a securement system for the patient interface and/or patient interface tubing. The patient interface has a body and at least one nasal prong extending from the body. The at least one nasal prong has a gas inlet for fluid communication with a supply of breathable gas, and a gas outlet configured to direct a flow of gas towards a nare of the user's nose. The at least one nasal prong further includes an exterior surface, at least a portion of the exterior surface is a sealing surface configured to seal the nare of the user's nose. The securement system has a two-part releasable attachment or connection arrangement, the arrangement comprising a first patch and a second patch.

Abstract: A humidification system can include a heater base, a chamber, and a breathing circuit. The heater base includes a heater plate positioned in a recessed region, and a heat conductive portion of the chamber is configured to contact the heater plate. The heater base includes a guard configured to control movement of the chamber into and out of the recessed region. The guard includes an anti-racking mechanism. The chamber includes an inlet port, an outlet port. A downward extension extends into the chamber from the inlet port, and a baffle is disposed at a lower end of the downward extension. A component of the breathing circuit can include a conduit hanging end cap for shipping and storage. The end cap can include a hanging component to allow the breathing circuit component to be hung from a medical stand. The system can detect when breathing circuits are connected in reverse.

Abstract: A computerized method is disclosed for grouping alerts through machine learning while implementing certain time constraints. The method includes receiving an alert to be assigned to any of a plurality of existing issues or to a newly created issue, the alert including a temporal field that includes a timestamp of an arrival time of the alert, wherein an issue is a grouping of one or more alerts, determining a subset of existing issues from the plurality of existing issues that each satisfy time constraints, wherein the time constraints correspond to (i) a time elapsed between a most recent alert of a first existing issue and a timestamp of the alert, or (ii) a maximum issue time length of the first existing issue, and deploying a trained machine learning model to assign the alert to either an existing issue of the subset of existing issues or a newly created issue.

Abstract: A humidification system for delivering humidified gases to a user can include a heater base, humidification chamber having an inlet, outlet, and associated fluid conduit, and breathing circuit including a supply conduit, inspiratory conduit, and optional expiratory conduit. The humidification system can include various features to help make set-up less difficult and time-consuming. For example, the supply conduit, inspiratory conduit, and optional expiratory conduit can be coupled into a one-piece circuit to aid set-up. Various components can be color-coded and can have corresponding structures to indicate which components should be connected to one another during set-up. Such features can also help make the set-up process more intuitive for an operator, which can reduce the need for specialized training and reduce the number of potential errors.

Abstract: A computerized method is disclosed for grouping alerts through machine learning. The method including receiving an alert to be assigned to any of a plurality of existing issues or to a newly created issue, wherein an issue is a grouping of alerts, determining a temporal distance between the alert and each of the existing issues, determining either of (i) a numerical distance between the alert and each of the existing issues for a particular numerical field, or (ii) a categorical distance between the alert and each of the existing issues for a particular categorical field, determining an overall distance between the alert and each of the existing issues, and assigning the alert to either (i) an existing issue having a shortest overall distance to the alert that satisfies one or more time constraints, or (ii) the newly created issue.

Abstract: A computerized method is disclosed for grouping alerts and providing remediation recommendation. The method includes receiving the alert to be assigned to an existing open issue or a newly created issue, wherein an issue is a grouping of one or more alerts, assigning the alert to either a first existing open issue or the newly created issue by determining a weighted sum of the distance between the feature vectors of the alert and each existing open issue, determining a weighted sum of the distance between the feature vectors of the alert and each closed issue, and generating a user interface that illustrates an assignment of the alert and at least one of (i) a closed issue having a shortest distance to the alert or (ii) recommended remediation efforts associated with the closed issue having the shortest distance to the alert.

Abstract: A computerized method is disclosed for retraining machine learning models based on user feedback. The method includes receiving user feedback indicating a change is to be made to an assignment of one or more alerts, wherein the one or more alerts were assigned by a machine learning model implementing a distance metric, wherein an issue is a grouping of at least one alert, constructing a convex optimization procedure to minimize an adjustment of weights of the distance metric, retraining the machine learning model by adjusting the weights of the distance metric in accordance with the convex optimization procedure, and evaluating one or more subsequently received alert using the retrained machine learning model. Changes to be made to the assignment include any of merging of two issues, splitting of two issues based on time or an alert field, or reassignment of an alert from a first issue to a second issue.

Abstract: A humidification system can include a heater base, a chamber, and a breathing circuit. The heater base includes a heater plate positioned in a recessed region, and a heat conductive portion of the chamber is configured to contact the heater plate. The heater base includes a guard configured to control movement of the chamber into and out of the recessed region. The guard includes an anti-racking mechanism. The chamber includes an inlet port, an outlet port. A downward extension extends into the chamber from the inlet port, and a baffle is disposed at a lower end of the downward extension. A component of the breathing circuit can include a conduit hanging end cap for shipping and storage. The end cap can include a hanging component to allow the breathing circuit component to be hung from a medical stand. The system can detect when breathing circuits are connected in reverse.

Abstract: A breathing circuit for use in respiratory therapy includes an inspiratory tube and an expiratory tube. The inspiratory tube of the breathing circuit has a smooth bore. The expiratory tube of the breathing circuit is corrugated. Preferably, the expiratory tube is vapor permeable. Using the combination of a smooth bore inspiratory tube with a corrugated expiratory tube has the unexpected result of improving the performance of the breathing circuit and its components.

Abstract: A humidification system for delivering humidified gases to a user can include a heater base, humidification chamber having an inlet, outlet, and associated fluid conduit, and breathing circuit including a supply conduit, inspiratory conduit, and optional expiratory conduit. The humidification system can include various features to help make set-up less difficult and time-consuming. For example, the supply conduit, inspiratory conduit, and optional expiratory conduit can be coupled into a one-piece circuit to aid set-up. Various components can be color-coded and can have corresponding structures to indicate which components should be connected to one another during set-up. Such features can also help make the set-up process more intuitive for an operator, which can reduce the need for specialized training and reduce the number of potential errors.

Abstract: An exemplary vascular neural interface device/configuration and method can be provided for at least one of stimulating or recording the nervous system. For example, a package can be provided which can be inserted within a blood vessel. The package can include at least one transducer, at least one electrode, and at least one integrated circuit. The at least one transducer can receive or transmit a wireless signal which is used to provide energy or communicate with the at least one integrated circuit to at least one of record or stimulate the nervous system using recording electronics or stimulating electronics.

Abstract: A humidification system for delivering humidified gases to a user can include a heater base, humidification chamber having an inlet, outlet, and associated fluid conduit, and breathing circuit including a supply conduit, inspiratory conduit, and optional expiratory conduit. The humidification system can include various features to help make set-up less difficult and time-consuming. For example, the supply conduit, inspiratory conduit, and optional expiratory conduit can be coupled into a one-piece circuit to aid set-up. Various components can be color-coded and can have corresponding structures to indicate which components should be connected to one another during set-up. Such features can also help make the set-up process more intuitive for an operator, which can reduce the need for specialized training and reduce the number of potential errors.

Abstract: A humidification system can include a heater base, a humidification chamber, and a breathing circuit. A cartridge can be removably coupled to the heater base. The cartridge can include various sensors, probes, sensor wire connectors, heater wire connectors, and/or other features. The cartridge can include features configured to mate with corresponding features on the humidification chamber and the heater base. The cartridge includes a memory, such as an EEPROM, or other suitable storage device. When the cartridge is installed on the heater base, the memory is electrically connected to a processor and/or memory of the heater base. Various models of cartridges can be produced for use with different humidification chambers, breathing circuits, and/or therapies. A connector can be configured to couple an inspiratory conduit to an outlet port of the humidification chamber. The connector can provide a pneumatic connection to the outlet port and an electrical connection to the cartridge.

Abstract: A circuit connector for a humidification system, the system comprising a base unit configured to be engaged by a humidification chamber. The circuit connector comprises an inlet to fluidly connect to an outlet of the humidification chamber to receive humidified gases therefrom, an outlet to sealably connect to or integral with a conduit for directing the humidified gases to a user, and an electrical terminal for electrically coupling the circuit connector to an electrical terminal associated with the base unit. The circuit connector may be releasably and lockably connectable to the outlet of the humidification chamber and/or orientation features may control orientation of component parts of the system as they are assembled.

Abstract: A humidification system for delivering humidified gases to a user can include a heater base, humidification chamber having an inlet, outlet, and associated fluid conduit, and breathing circuit including a supply conduit, inspiratory conduit, and optional expiratory conduit. The humidification system can include various features to help make set-up less difficult and time-consuming. For example, the supply conduit, inspiratory conduit, and optional expiratory conduit can be coupled into a one-piece circuit to aid set-up. Various components can be color-coded and can have corresponding structures to indicate which components should be connected to one another during set-up. Such features can also help make the set-up process more intuitive for an operator, which can reduce the need for specialized training and reduce the number of potential errors.

Abstract: A circuit connector for a humidification system, the system comprising a base unit configured to be engaged by a humidification chamber. The circuit connector comprises an inlet to fluidly connect to an outlet of the humidification chamber to receive humidified gases therefrom, an outlet to sealably connect to or integral with a conduit for directing the humidified gases to a user, and an electrical terminal for electrically coupling the circuit connector to an electrical terminal associated with the base unit. The circuit connector may be releasably and lockably connectable to the outlet of the humidification chamber and/or orientation features may control orientation of component parts of the system as they are assembled.

Abstract: A humidification system can include a heater base, a humidification chamber, and a breathing circuit. A cartridge can be removably coupled to the heater base. The cartridge can include various sensors, probes, sensor wire connectors, heater wire connectors, and/or other features. The cartridge can include features configured to mate with corresponding features on the humidification chamber and the heater base. The cartridge includes a memory, such as an EEPROM, or other suitable storage device. When the cartridge is installed on the heater base, the memory is electrically connected to a processor and/or memory of the heater base. Various models of cartridges can be produced for use with different humidification chambers, breathing circuits, and/or therapies. A connector can be configured to couple an inspiratory conduit to an outlet port of the humidification chamber. The connector can provide a pneumatic connection to the outlet port and an electrical connection to the cartridge.