Abstract: A submerged combustion apparatus for heating a liquid including a liquid vessel that contains the liquid, a combustion chamber including a combustion chamber body, an inlet and a plurality of discharge ports, the combustion chamber body being positioned in the vessel so that at least the discharge ports are submerged in liquid in use, a burner that allows an air/fuel mixture to be burned at least partially within the combustion chamber thereby causing bubbles of heated gaseous combustion products to be emitted from the discharge ports so as to heat the liquid and a guide surface spaced apart from and extending along at least part of a length of a combustion chamber body outer surface so as to guide bubbles emitted from the discharge ports so that the bubbles are at least partially constrained to flow between the combustion chamber body outer surface and the guide surface.

Abstract: A submerged combustion apparatus for heating a liquid including a liquid vessel that contains the liquid, a combustion chamber including a combustion chamber body, an inlet and a plurality of discharge ports, the combustion chamber body being positioned in the vessel so that at least the discharge ports are submerged in liquid in use, a burner that allows an air/fuel mixture to be burned at least partially within the combustion chamber thereby causing bubbles of heated gaseous combustion products to be emitted from the discharge ports so as to heat the liquid and a guide surface spaced apart from and extending along at least part of a length of a combustion chamber body outer surface so as to guide bubbles emitted from the discharge ports so that the bubbles are at least partially constrained to flow between the combustion chamber body outer surface and the guide surface.

Abstract: A method of determining antimicrobial activity of an agent can include providing a well, wherein the well contains at least one antimicrobial agent, the well further including at least two electrodes. A sample of a microbe can be added into the well and a voltage pulsed between the electrodes. An electrical property can be sampled and recorded. In another aspect, a method of identifying at least one microbe includes taking a sample containing the at least one microbe, isolating the at least one microbe from the sample, dividing the at least one microbe into at least one well, wherein each well contains at least one antimicrobial agent and at least two electrodes. A voltage is pulsed between the at least two electrodes, an electrical property is sampled during the pulsing and recorded. In another aspect, a diagnostic device for detecting at least one microbe is presented.

Abstract: A method of determining antimicrobial activity of an agent can include providing a well, wherein the well contains at least one antimicrobial agent, the well further including at least two electrodes. A sample of a microbe can be added into the well and a voltage pulsed between the electrodes. An electrical property can be sampled and recorded. In another aspect, a method of identifying at least one microbe includes taking a sample containing the at least one microbe, isolating the at least one microbe from the sample, dividing the at least one microbe into a at least one well, wherein each well contains at least one antimicrobial agent and at least two electrodes. A voltage is pulsed between the at least two electrodes, an electrical property is sampled during the pulsing and recorded. In another aspect, a diagnostic device for detecting at least one microbe is presented.

Abstract: A method of determining antimicrobial activity of an agent can include providing a well, wherein the well contains at least one antimicrobial agent, the well further including at least two electrodes. A sample of a microbe can be added into the well and a voltage pulsed between the electrodes. An electrical property can be sampled and recorded. In another aspect, a method of identifying at least one microbe includes taking a sample containing the at least one microbe, isolating the at least one microbe from the sample, dividing the at least one microbe into a at least one well, wherein each well contains at least one antimicrobial agent and at least two electrodes. A voltage is pulsed between the at least two electrodes, an electrical property is sampled during the pulsing and recorded. In another aspect, a diagnostic device for detecting at least one microbe is presented.