Abstract: The invention is related to multivalent immunogenic compositions comprising more than one S. pneumoniae polysaccharide protein conjugates, wherein each of the conjugates comprises a polysaccharide from an S. pneumoniae serotype conjugated to a carrier protein, wherein the serotypes of S. pneumoniae are as defined herein. Also provided are methods for inducing a protective immune response in a human patient comprising administering the multivalent immunogenic compositions of the invention to the patient. The multivalent immunogenic compositions are useful for providing protection against S. pneumoniae infection and diseases caused by S. pneumoniae. The compositions of the invention are also useful as part of treatment regimes that provide complementary protection for patients that have been vaccinated with a multivalent vaccine indicated for the prevention of pneumococcal disease.

Abstract: Various disclosed embodiments include illustrative systems, structures, and methods. In an illustrative embodiment, a system includes a power transmitter operably couplable to a source of electrical power and configured to wirelessly transmit electrical power and a power receiver alignable with the power transmitter on an opposing side of a non-conductive panel of a structure. The power receiver is configured to generate electrical power responsive to the electrical power wirelessly transmitted by the power transmitter.

Abstract: A system for autonomous or semi-autonomous operation of a vehicle is disclosed. The system includes a machine automation portal (MAP) application configured to enable a computing device to (a) display a map of a work site and (b) provide a graphical user interface that enables a user to (i) define a boundary of an autonomous operating zone on the map and (ii) define a boundary of one or more exclusion zones. The system also includes a robotics processing unit configured to (a) receive the boundary of the autonomous operating zone and the boundary of each exclusion zone from the computing device, (b) generate a planned command path that the vehicle will travel to perform a task within the autonomous operating zone while avoiding each exclusion zone, and (c) control operation of the vehicle so that the vehicle travels the planned command path to perform the task.

Abstract: Methods, systems, and apparatus, including computer programs encoded on a computer storage medium, that identify and issue search queries expected to be issued in the future. A set of search queries that have been issued by multiple user devices can be obtained. For each query instance, contextual data can be obtained. A first query and its contextual data can be input to a model that outputs the query's likelihood of being issued in the future. The model can be trained using contextual data for training queries and a corresponding labels for the training queries. The learning model outputs the first query's likelihood of being issued in future, and this query is stored as a repeatable query if the likelihood satisfying a repeatability threshold. Subsequently, a stored repeatable query is issued upon a selection of a user selectable interface component and the search engine provides search results for the query.

Abstract: A surgical end effector assembly includes first and second jaw members configured to grasp tissue. Each of the first and second jaw members includes a proximal flange portion and a distal body portion. The proximal flange portions are pivotably coupled to one another to move the distal body portions between a spaced-apart position and an approximated position.

Abstract: In one aspect of the present disclosure, a disc brake rotor assembly is provided that includes a disc brake rotor and a wheel hub. One of the disc brake rotor and the wheel hub includes a plurality of pairs of partial keyways and the other of the disc brake rotor and the wheel hub includes intermediate partial keyways configured to fit intermediate the pairs of partial keyways to form keyways. The disc brake rotor assembly further includes a plurality of fasteners configured to be received in the keyways to secure the disc brake rotor and the wheel hub together.

Abstract: A cable gland including an entry component including an inner surface with an abutment, a backnut removably attachable to the entry component, a cavity extending through the entry component and the backnut, and a grounding device configured to rest against the abutment, the grounding device including a rim, an inner edge, and a plurality of fingers extending inward and downward from the inner edge, wherein the grounding device is comprised of a conductive material, such as spring steel.

Abstract: Systems and methods for the dynamic selection of IP address in email platforms, and the synchronization of hostnames and IP addresses in such platforms, are disclosed.

Abstract: A system for autonomous or semi-autonomous operation of a vehicle is disclosed. The system includes a machine automation portal (MAP) application configured to enable a computing device to (a) display a map of a work site and (b) provide a graphical user interface that enables a user to (i) define a boundary of an autonomous operating zone on the map and (ii) define a boundary of one or more exclusion zones. The system also includes a robotics processing unit configured to (a) receive the boundary of the autonomous operating zone and the boundary of each exclusion zone from the computing device, (b) generate a planned command path that the vehicle will travel to perform a task within the autonomous operating zone while avoiding each exclusion zone, and (c) control operation of the vehicle so that the vehicle travels the planned command path to perform the task.

Abstract: Provided are methods for the parenteral use of 3-methoxy-N-[3-(2-methylpyrazol-3-yl)-4-(2-morpholin-4-ylethoxy)phenyl]benzamide, or a pharmaceutically acceptable salt, hydrate, or solvate thereof, and the sequential use of parenteral and oral formulations of 3-methoxy-N-[3-(2-methylpyrazol-3-yl)-4-(2-morpholin-4-ylethoxy)phenyl]benzamide, or a pharmaceutically acceptable salt, hydrate, or solvate thereof.

Abstract: A mixed reality virtual environment is sharable among multiple users through the use of multiple view modes that are selectable by a presenter. Multiple users may wish to view a common virtual object, such as one that is used for educational purposes, such as a piece of art in a museum, automobile, biological specimen, chemical compound, etc. The virtual object may be presented in a virtual room to any number of users. A presentation may be controlled by a presenter (e.g., a teacher of a class of students) that leads multiple participants (e.g., students) through information associated with the virtual object. Use of different viewing modes allows individual users to see different virtual content despite being in a shared viewing space or alternatively, to see the same virtual content in different locations within a shared space.

Abstract: A computer system for manipulating, combining, or composing dynamic sounds accesses a package of one or more music stems. The computer system then receive an input variable from one or more vehicle sensors. The one or more vehicle sensors measure an aspect of driving parameters of a vehicle. In response to the input variable, the computer system generate a particular audio effect with the one or more music stems.

Abstract: A containment plow adapted to be mounted to a vehicle such as a skid steer, a wheeled loader, or a tractor, comprises a moldboard frame, a moldboard mounted to the moldboard frame, a moldboard cutting edge mounted to a lower edge of the moldboard and comprising a plurality of cutting edge segments, each moldboard cutting edge segment mounted so as to have two rotational degrees of freedom movement relative to the moldboard and one translational degree of freedom movement relative to the moldboard, and a moldboard extension and wing assembly connected to the moldboard frame adjacent each end of the moldboard.

Abstract: A containment plow adapted to be mounted to a vehicle such as a skid steer, a wheeled loader, or a tractor comprises a moldboard frame, a moldboard mounted to the moldboard frame, a wing pivotally connected to the moldboard frame adjacent each end of the moldboard, a moldboard cutting edge mounted to a lower edge of the moldboard and comprising a plurality of cutting edge segments, and a wing cutting edge mounted to a lower edge of each wing. Each moldboard cutting edge segment is mounted so as to have two rotational degrees of freedom movement relative to the moldboard and one translational degree of freedom movement relative to the moldboard. Each wing cutting edge is mounted so as to have two rotational degrees of freedom movement relative to the wing.

Abstract: A containment plow adapted to be mounted to a vehicle such as a skid steer, a wheeled loader, or a tractor comprises a moldboard frame, a moldboard mounted to the moldboard frame, a wing pivotally connected to the moldboard frame adjacent each end of the moldboard, a moldboard cutting edge mounted to a lower edge of the moldboard and comprising a plurality of cutting edge segments, and a wing cutting edge mounted to a lower edge of each wing. Each moldboard cutting edge segment is mounted so as to have two rotational degrees of freedom movement relative to the moldboard and one translational degree of freedom movement relative to the moldboard. Each wing cutting edge is mounted so as to have two rotational degrees of freedom movement relative to the wing.

Abstract: Disclosed herein are various cable gel seal arrangements and thermoplastic gels useful therein. The thermoplastic gels are prepared from a composition including a styrene triblock copolymer, a styrene diblock copolymer, an oil extender, and an additive selected from poly(2,6-dimethyl-1,4-phenylene oxide), a C9 resin, poly(alpha-methylstyrene), a coumarone-indene resin, and combinations thereof, wherein the additive has a Tg from about 95° C. to about 200° C. The thermoplastic gels advantageously exhibit low compression set.

Abstract: A valve dispenses flowable product from a container. The valve includes a mounting cup for mounting the valve on the container, a seal supported on the mounting cup, and a valve stem extending through the seal. The seal and the valve stem define a generally annular passage section of the valve passage that extends longitudinally along the valve axis radially between the valve stem and the seal. At least one of the valve stem and the seal includes a baffle extending transverse to the valve axis, the baffle defining a flow restriction along the generally annular passage section.

Abstract: Disclosed herein are various cable gel seal arrangements and thermoplastic gels useful therein. The thermoplastic gels are prepared from a composition including a styrene triblock copolymer, a styrene diblock copolymer, an oil extender, and an additive selected from poly(2,6-dimethyl-1,4-phenylene oxide), a C9 resin, poly(alpha-methylstyrene), a coumarone-indene resin, and combinations thereof, wherein the additive has a Tg from about 95° C. to about 200° C. The thermoplastic gels advantageously exhibit low compression set.

Abstract: A computer system for dynamic syncing of content within a communication interface receives an indication, from a first communication interface, to share digital content with a second user, wherein the digital content is contained with a digital file. The computer system then a copy of the digital file to the second user. The digital content within to copy of the digital file is displayed or played to the second user within a second communication interface. The computer system then receives a synchronization command from the first user. In response to the synchronization command, the computer system causes the second communication interface to mirror the first user's view of the digital content.