Abstract: Provided herein are methods and compositions for treating von Willebrand disease with platelets, platelet derivatives, and/or thrombosomes.

Abstract: In some embodiments provided herein is a method of treating a coagulopathy in a subject, the method including administering to the subject in need thereof an effective amount of a composition including platelets or platelet derivatives and an incubating agent including one or more salts, a buffer, optionally a cryoprotectant, and optionally an organic solvent.

Abstract: An improved headset is provided to selectively distribute the weight of the headset while securely registering the headset comfortably on a wearer's head. The headset comprises one or more compliant arms and a frame to selectively distribute the weight of the headset and secure the headset to the wearer's head without the need for straps or leavers. The compliant arms provide a normalizing force through elastic body deformation to selectively distribute the weight of the headset.

Abstract: One variation of a method includes: conveying a mixture of air in a working fluid through a compressor to heat and pressurize the mixture to promote absorption of carbon dioxide into the working fluid; depositing the mixture in a high-pressure vessel configured to remove air from the mixture of carbon dioxide in the working fluid; conveying the mixture through a turbine to reduce pressure and promote desorption of carbon dioxide from the working fluid; depositing the mixture in a low-pressure vessel for removal of carbon dioxide; in response to a temperature of an interior environment falling below a target range, conveying the working fluid through a heating element configured to transfer heat from the working fluid into the interior environment; and, in response to the temperature exceeding the target range, conveying the working fluid through a cooling element configured to transfer heat from the working fluid into an exterior environment.

Abstract: A method of fabricating a multi-element fiber scanner includes providing a fiber optic cable having a cladding region and a fiber core and focusing a laser beam at a series of predetermined locations inside the cladding region of the fiber optic cable. The method also includes creating a plurality of damage sites at the predetermined locations, exposing the fiber optic cable to an etchant solution, and preferentially etching the plurality of damage sites to form a base having a base plane and a longitudinal axis orthogonal to the base plane, a retention collar disposed a predetermined distance along the longitudinal axis from the base, a first fiber link including the fiber core, passing through the base plane, and joined to the retention collar, and a plurality of additional links joined to the base, extending from the base to the retention collar, and joined to the retention collar.

Abstract: A method of fabricating a multi-element fiber scanner includes providing a fiber optic cable having a cladding region and a fiber core and focusing a laser beam at a series of predetermined locations inside the cladding region of the fiber optic cable. The method also includes creating a plurality of damage sites at the predetermined locations, exposing the fiber optic cable to an etchant solution, and preferentially etching the plurality of damage sites to form a base having a base plane and a longitudinal axis orthogonal to the base plane, a retention collar disposed a predetermined distance along the longitudinal axis from the base, a first fiber link including the fiber core, passing through the base plane, and joined to the retention collar, and a plurality of additional links joined to the base, extending from the base to the retention collar, and joined to the retention collar.

Abstract: A method of operating a multi-axis fiber scanner having a base including a base plane includes providing a source of electromagnetic radiation, directing the electromagnetic radiation through a fiber link that passes through the base plane of the base along a longitudinal axis orthogonal to the base plane, and supporting a retention collar positioned a distance from the base plane. The method also includes actuating a first piezoelectric actuator among a plurality of piezoelectric actuators to decrease the distance between a first side of the base and the retention collar, actuating a second piezoelectric actuator among the plurality of piezoelectric actuators to increase the distance between a second side of the base and the retention collar, and scanning the fiber link in a scanning plane.

Abstract: An improved headset is provided to selectively distribute the weight of the headset while securely registering the headset comfortably on a wearer's head. The headset comprises one or more compliant arms and a frame to selectively distribute the weight of the headset and secure the headset to the wearer's head without the need for straps or leavers. The compliant arms provide a normalizing force through elastic body deformation to selectively distribute the weight of the headset.

Abstract: An improved headset is provided to selectively distribute the weight of the headset while securely registering the headset comfortably on a wearer's head. The headset comprises one or more compliant arms and a frame to selectively distribute the weight of the headset and secure the headset to the wearer's head without the need for straps or leavers. The compliant arms provide a normalizing force through elastic body deformation to selectively distribute the weight of the headset.

Abstract: A method of operating a multi-axis fiber scanner having a base including a base plane includes providing a source of electromagnetic radiation, directing the electromagnetic radiation through a fiber link that passes through the base plane of the base along a longitudinal axis orthogonal to the base plane, and supporting a retention collar positioned a distance from the base plane. The method also includes actuating a first piezoelectric actuator among a plurality of piezoelectric actuators to decrease the distance between a first side of the base and the retention collar, actuating a second piezoelectric actuator among the plurality of piezoelectric actuators to increase the distance between a second side of the base and the retention collar, and scanning the fiber link in a scanning plane.

Abstract: A multi-element fiber scanner for scanning electromagnetic imaging radiation includes a base having a base plane and a longitudinal axis orthogonal to the base plane and a fiber link passing through the base in a direction parallel to the longitudinal axis. The fiber link is operatively coupled to at least one electromagnetic radiation source. The multi-element fiber scanner also includes a retention collar disposed a predetermined distance along the longitudinal axis from the base and a first set and a second set of piezoelectric tubes. First and second piezoelectric tubes of the first set are joined to the base and extends from the base and first and second piezoelectric tubes of the second set are joined to the retention collar and extend from the retention collar.

Abstract: A multi-element fiber scanner for scanning electromagnetic imaging radiation includes a base having a base plane and a longitudinal axis orthogonal to the base plane and a fiber link passing through the base in a direction parallel to the longitudinal axis. The fiber link is operatively coupled to at least one electromagnetic radiation source. The multi-element fiber scanner also includes a retention collar disposed a predetermined distance along the longitudinal axis from the base and a first set and a second set of piezoelectric tubes. First and second piezoelectric tubes of the first set are joined to the base and extends from the base and first and second piezoelectric tubes of the second set are joined to the retention collar and extend from the retention collar.

Abstract: A multi-element fiber scanner for scanning electromagnetic imaging radiation includes a base having a base plane and a longitudinal axis orthogonal to the base plane and a first fiber link passing through the base in a direction parallel to the longitudinal axis. The first fiber link is operatively coupled to at least one electromagnetic radiation source. The multi-element fiber scanner also includes a plurality of additional links joined to the base and extending from the base and a retention collar disposed a predetermined distance along the longitudinal axis from the base. The first fiber link and the plurality of fiber links are joined to the retention collar.

Abstract: A multi-element fiber scanner for scanning electromagnetic imaging radiation includes a base having a base plane and a longitudinal axis orthogonal to the base plane and a first fiber link passing through the base in a direction parallel to the longitudinal axis. The first fiber link is operatively coupled to at least one electromagnetic radiation source. The multi-element fiber scanner also includes a plurality of additional links joined to the base and extending from the base and a retention collar disposed a predetermined distance along the longitudinal axis from the base. The first fiber link and the plurality of fiber links are joined to the retention collar.

Abstract: An improved headset is provided to selectively distribute the weight of the headset while securely registering the headset comfortably on a wearer's head. The headset comprises one or more compliant arms and a frame to selectively distribute the weight of the headset and secure the headset to the wearer's head without the need for straps or leavers. The compliant arms provide a normalizing force through elastic body deformation to selectively distribute the weight of the headset.