Abstract: Systems and methods for providing targeted messages to users of media presentation systems. In accordance with one embodiment of the invention, a message server may communicate with a media presentation system, such as a media player for streaming video and audio, to present targeted messages to the user of the media presentation system. The targeted messages include messages to promote marketing campaigns, advertising, and the like. The targeted messages may be presented in various formats, including a graphical display, an audio presentation, a graphical and audio presentation, URL links, and/or interactive windows. Information about the media presentation systems and information about the marketing campaigns are maintained by the message server. The message server may update the foregoing information in accordance with the interaction between the message server and the media presentation system.