Abstract: The present invention provides compounds, compositions thereof, and methods of using the same for the inhibition of HPK1, and the treatment of HPK1-mediated disorders.

Abstract: A system includes a sensor configured at a first position to sense an orientation of an electricity meter. The electricity meter can be configured at a second position. The electricity meter can be configured at a normal orientation to measure delivered energy sent to one or more locations and received energy received from the one or more locations. The electricity meter can be configured at an inverted orientation to identify and measure the delivered energy sent to the one or more locations and the received energy received from the one or more locations. The sensor is configured to identify when the electricity meter is in the normal orientation, and when the electricity meter is in the inverted orientation. A display is configured within the electricity meter.

Abstract: A method and system for aligning a component within a turbine casing, and a related turbine casing, are disclosed. In a top-on position, a location of a reference point and another, vertically spaced reference point on the lower casing are measured. After removing at least the upper casing, the reference points' locations are measured again, and the locations of a reference point on an upper surface of the HJ flange are measured. A prediction offset value is calculated for the component support position in the top-on position based on the locations. The prediction offset value may include a vertical adjustment based, in part, on a translation of a triangular spatial relationship of a number of the reference points and/or a tilt angle, a horizontal adjustment, and a HJ flange surface distortion adjustment. The component support position is adjusted by the prediction offset value to improve alignment.

Abstract: A shingle coating asphalt composition is provided that is produced from a paving grade asphalt. The asphalt composition comprises a paving-grade asphalt that has been modified with one or more polymer additives; and a secondary additive comprising one or more of a viscosity reducing agent, a wax, a salt of a fatty acid ester, and an amide of a fatty acid. The shingle coating asphalt coating composition is used to make a shingle. The shingle includes a substrate, the asphalt, and roofing granules.

Abstract: A button for a drug delivery device with a reduced operating loudness includes a plate-like button body forming a touch surface, wherein the plate-like button body is coupled by an axial supporting member to a noise-generating interface of the drug delivery device and movable into a longitudinal direction of the drug delivery device, wherein the plate-like button body includes a material composite with at least one first component consisting of a first material and at least one second component consisting of a second material different from the first material, wherein the at least one first component and the at least one second component are coupled via at least one coupling plane that is at least sectionwise slanted or perpendicular to the longitudinal direction. Further, the disclosure describes a button assembly for a drug delivery device which is shock resistant.

Abstract: A configurable data center platform includes an enclosure configured to affix to a support structure, the enclosure configured for housing one or more processing systems that form a data center, one or more transceivers configured to enable the one or more processing systems to communicate with one or more remote devices, one or more sensors; and an electrical power distribution subsystem configured to condition a received electrical current to one or more conditioned electrical currents that power the one or more processing systems and the one or more sensors, wherein the enclosure comprises a cooling system that removes heat from the one or more processing systems and the one or more sensors.

Abstract: An integrated tool processing system and a wellsite monitoring system for a wellsite. The integrated tool processing system includes a tool assembler, a tool lift, and a tool transporter. The tool assembler includes a tool conveyor and a gun builder. The tool lift is connected by a tool stager to the tool assembler. The tool lift includes a lift base to receive the downhole tool and a lift arm to lift the downhole tool. The tool transporter includes a vehicle and a boom for connection to the downhole tool. The vehicle and the boom carry the downhole tool into position for delivery at the wellsite. The wellsite monitoring system includes wellsite sensors to collect wellsite data, wellsite monitors to receive and analyze the wellsite data, and a central station to collect and further analyze the wellsite data and to operate the tool processing system based on the combined wellsite data.

Abstract: Systems and techniques are provided for vehicle safety technologies. An example method can include determining, based on sensor data captured by an autonomous vehicle, a first position of a different vehicle and a second position of one or more objects; determining, based on the first position of the different vehicle and the second position of the one or more objects, a risk of a collision between the different vehicle and the one or more objects; and based on a determination that the risk of the collision exceeds a threshold, outputting an alert representing a warning of the collision between the different vehicle and the one or more objects, the alert being directed to at least one of the different vehicle and the one or more objects.

Abstract: An integrated detonation assembly of a perforating unit includes a detonator assembly and a charge assembly. The detonator assembly is positioned in the outer housing and comprises a bulkhead connected to the outer housing; a charge connector connected to the bulkhead, the charge connection having a connection end; a detonator carried by the charge connector; and a trigger coupled to the detonator and to a remote actuator. The charge assembly is insertable into the outer housing, and comprises a charge tube to support shaped charges therein; a charge feedthru; and a receiver. The receiver is at an opposite end of the charge tube, and has a receptacle shaped to matingly receive the connection end of the charge connector and to engage the trigger whereby, upon insertion of the charge assembly into the outer housing, the receiver is oriented and communicatively secured to the detonator assembly.

Abstract: An apparatus for detecting a condition or authenticity of one or more electronic devices includes an enclosure having an antenna integrated therewithin, a fixture mounted within a hollow interior of the enclosure, the fixture being configured to receive the one or more electronic devices and connect one or more signals to each of the one or more electronic devices and a sensor and controller assembly connected to the antenna and configured to process a signature of an emission of a radiofrequency (RF) energy from of one or more electronic devices having the one or more signals connected thereto.

Abstract: One embodiment is an apparatus for inhibiting accidental contact by a human with a tail rotor connected to an empennage of an aircraft. The apparatus includes an inverted V-tail connected to an empennage of the aircraft forward of the tail rotor, the inverted V-tail stabilizer comprising a first V-tail stabilizer on a side of the empennage to which the tail rotor is connected and a second V-tail stabilizer on a side of the empennage opposite the side of the empennage to which the tail rotor is connected; and a shroud bar having a first end connected to an outboard end of the first V-tail stabilizer and a second end opposite the first end connected to the empennage aft of the tail rotor, wherein a horizontal distance from the shroud bar to the tail rotor is greater than a length of an arm of the human.

Abstract: A product produced by a process that includes shredding a set of tires into a volume of tire rubber segments, the set of tires selected from car tires and truck tires such that specific percentage amounts of rubber from car tires and rubber from truck tires are included within the volume of tire rubber segments. The process additionally including thermally depolymerizing the volume of tire rubber segments into a volume of carbonaceous material; comminuting the volume of carbonaceous material; removing from the volume of carbonaceous material agglomerates larger than the maximum agglomerate diameter; within a mixer, mixing the volume of carbonaceous material with a binding agent over a first interval, the mixer inducing formation of a set of pellets of a range of pellet diameters; and removing from the set of pellets a first subset of pellets larger than a maximum pellet size.

Abstract: Drive envelope determination is described. In an example, a vehicle can capture sensor data while traversing an environment and can provide the sensor data to computing system(s). The sensor data can indicate agent(s) in the environment and the computing system(s) can determine, based on the sensor data, a planned path through the environment relative to the agent(s). The computing system(s) can also determine lateral distance(s) to the agent(s) from the planned path. In an example, the computing system(s) can determine modified distance(s) based at least in part on the lateral distance(s) and information about the agents. The computing system can determine a drive envelope based on the modified distance(s) and can determine a trajectory in the drive envelope.

Abstract: A vehicle computing system may implement techniques to control a vehicle to avoid collisions between the vehicle and agents (e.g., dynamic objects) in an environment. The techniques may include generating a representation of a path of the vehicle through an environment as a polygon. The vehicle computing system may compare the two-dimensional path with a trajectory of an agent determined using sensor data to determine a collision zone between the vehicle and the agent. The vehicle computing system may determine a risk of collision based on predicted velocities and probable accelerations of the vehicle and the agent approaching and traveling through the collision zone. Based at least in part on the risk of collision, the vehicle computing system may cause the vehicle to perform an action.

Abstract: The present disclosure pertains to a system and method for monitoring lung disease in a patient that is based on information that is derivable from home therapy devices including a ventilation therapy device and an oxygen saturation monitor such as a pulse oximeter. The measured parameters are used to model shunt fraction and a volume of dead space. Based on changes in gas exchange and results of a nitrogen washout test, a change in gas exchange impairment in the patient is observed and is then used to determine progression of a disease, identify a cause of the impairment, and/or to guide treatment of the patient.

Abstract: A handle assembly for an access panel is described and includes a handle connected to a support structure integrated into and covered by a skin of the access panel, the handle comprising a grip portion and upper and lower flanges extending perpendicularly from the grip portion and having first ends connected to the grip portion and second ends connected to the support structure; and a cover disposed over an opening in the access panel skin and selectively transitionable between a closed position and an open position, the opening situated relative to the handle such that the handle is concealed when the cover is in a closed position and accessible via the opening when the cover is in an open position.

Abstract: Disclosed are systems and methods for specifying goals and behavioral parameters for planning systems of autonomous vehicles. In some aspects, a method includes receiving, by a mission manager in an autonomous vehicle (AV), a mission from an input source of the AV, the mission comprising a request for a task that the AV is to fulfill; deconflicting the mission with one or more other missions of the AV to generate a ranked list of missions; selecting a target mission from the ranked list of missions in accordance with priorities corresponding to each mission in the ranked list of missions; generating one or more scenarios based on the target mission, the one or more scenarios comprising encoded representations of local and geometric terms to cause the target mission to be fulfilled by the AV; and dispatching the one or more scenarios to a planner layer of the AV.

Abstract: A resolver assembly for a ducted-rotor aircraft is configured to detect and measure rotation of a spindle of the aircraft. The resolver assembly includes first and second gear-driven resolvers. The first and second resolvers are coupled about a shared pivot axis and are independently pivotable about the pivot axis to maintain engagement of the first and second resolvers with the spindle of the aircraft. The resolver assembly is configured such that the first and second resolvers are biased toward the spindle. The input shafts of the first and second resolvers are spaced from the pivot axis through respective first and second distances that extend outward from the pivot axis along respective first and second radial directions. The first distance is equal to the second distance and the first radial direction is not coincident with the second radial direction.

Abstract: Techniques are discussed for controlling a vehicle, such as an autonomous vehicle, based on occluded areas in an environment. An occluded area can represent areas where sensors of the vehicle are unable to sense portions of the environment due to obstruction by another object. An occlusion grid representing the occluded area can be stored as map data or can be dynamically generated. An occlusion grid can include occlusion fields, which represent discrete two- or three-dimensional areas of driveable environment. An occlusion field can indicate an occlusion state and an occupancy state, determined using LIDAR data and/or image data captured by the vehicle. An occupancy state of an occlusion field can be determined by ray casting LIDAR data or by projecting an occlusion field into segmented image data. The vehicle can be controlled to traverse the environment when a sufficient portion of the occlusion grid is visible and unoccupied.