Patents by Inventor William Arndt
William Arndt has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).
-
Patent number: 10842835Abstract: Methods utilizing vaccinia virus with mutations in E3L to infect and cause lysis of cancer cells with less than normal protein levels of RIP3 and/or DAI. Further, the disclosed vaccinia viruses with mutations in E3L cannot replicate well in cells with normal expression or upregulation of RIP3, DAI, and/or MLKL.Type: GrantFiled: May 25, 2017Date of Patent: November 24, 2020Assignee: ARIZONA BOARD OF REGENTS ON BEHALF OF ARIZONA STATE UNIVERSITYInventors: Bertram Jacobs, Heather Koehler, William Arndt, Karen Kibler, Kelly Trainor, Chandra Mitnik, Jeffrey Langland
-
Publication number: 20190183947Abstract: Methods utilizing vaccinia virus with mutations in E3L to infect and cause lysis of cancer cells with less than normal protein levels of RIP3 and/or DAI. Further, the disclosed vaccinia viruses with mutations in E3L cannot replicate well in cells with normal expression or upregulation of RIP3, DAI, and/or MLKL.Type: ApplicationFiled: May 25, 2017Publication date: June 20, 2019Inventors: Bertram Jacobs, Heather Koehler, William Arndt, Karen Kibler, Kelly Trainor, Chandra Mitnik, Jeffrey Langland
-
Patent number: 10126299Abstract: The present invention, in part, relates to methods and apparatuses for on-chip amplification and/or detection of various targets, including biological targets and any amplifiable targets. In some examples, the microculture apparatus includes a single-use, normally-closed fluidic valve that is initially maintained in the closed position by a valve element bonded to an adhesive coating. The valve is opened using a magnetic force. The valve element includes a magnetic material or metal. Such apparatuses and methods are useful for in-field or real-time detection of targets, especially in limited resource settings.Type: GrantFiled: November 22, 2017Date of Patent: November 13, 2018Assignee: National Technology & Engineering Solutions of Sandia, LLCInventors: Jason C. Harper, Thayne L. Edwards, Bryan Carson, Melissa Finley, William Arndt
-
Publication number: 20180095083Abstract: The present invention, in part, relates to methods and apparatuses for on-chip amplification and/or detection of various targets, including biological targets and any amplifiable targets. In some examples, the microculture apparatus includes a single-use, normally-closed fluidic valve that is initially maintained in the closed position by a valve element bonded to an adhesive coating. The valve is opened using a magnetic force. The valve element includes a magnetic material or metal. Such apparatuses and methods are useful for in-field or real-time detection of targets, especially in limited resource settings.Type: ApplicationFiled: November 22, 2017Publication date: April 5, 2018Inventors: Jason C. Harper, Thayne L. Edwards, Bryan Carson, Melissa Finley, William Arndt
-
Patent number: 9857370Abstract: The present invention, in part, relates to methods and apparatuses for on-chip amplification and/or detection of various targets, including biological targets and any amplifiable targets. In some examples, the microculture apparatus includes a single-use, normally-closed fluidic valve that is initially maintained in the closed position by a valve element bonded to an adhesive coating. The valve is opened using a magnetic force. The valve element includes a magnetic material or metal. Such apparatuses and methods are useful for in-field or real-time detection of targets, especially in limited resource settings.Type: GrantFiled: January 16, 2014Date of Patent: January 2, 2018Assignee: National Technology & Engineering Solutions of Sandia, LLCInventors: Jason C. Harper, Thayne L. Edwards, Bryan Carson, Melissa Finley, William Arndt
-
Patent number: 9291210Abstract: A dual mass flywheel and dual clutch module assembly includes a connector plate and a drive plate. The connector plate is fastened to a center plate of the dual clutch module and has a plurality of castellation tabs disposed on an inner periphery of the connector plate. The drive plate drivingly connected to a flywheel member of the dual mass flywheel and includes a plurality of castellation tabs disposed on an inner periphery of the drive plate. The plurality of castellation tabs of the connector plate are interleaved with the plurality of castellation tabs of the drive plate.Type: GrantFiled: August 11, 2014Date of Patent: March 22, 2016Assignee: GM Global Technology Operations LLCInventors: Tejinder Singh, Randal William Arndt, John A. Diemer, Rima Philippin
-
Publication number: 20160040727Abstract: A dual mass flywheel and dual clutch module assembly includes a connector plate and a drive plate. The connector plate is fastened to a center plate of the dual clutch module and has a plurality of castellation tabs disposed on an inner periphery of the connector plate. The drive plate drivingly connected to a flywheel member of the dual mass flywheel and includes a plurality of castellation tabs disposed on an inner periphery of the drive plate. The plurality of castellation tabs of the connector plate are interleaved with the plurality of castellation tabs of the drive plate.Type: ApplicationFiled: August 11, 2014Publication date: February 11, 2016Applicant: GM Global Technology Operations LLCInventors: Tejinder Singh, Randal William Arndt, John A. Diemer, Rima Philippin
-
Patent number: 9051980Abstract: A torque transmitting device for use in an automotive transmission is provided. The device includes an inner annular race and an outer annular race disposed concentrically around the inner annular race. A selector plate is disposed adjacent to the inner and outer annular races, the selector plate being movable with respect to the inner and outer races. Multiple control elements are pivotally connected to the selector plate. The control elements are disposed between the inner and outer races. A plurality of sprag elements is disposed between the inner and outer races. Each sprag element is disposed adjacent to a control element.Type: GrantFiled: April 26, 2013Date of Patent: June 9, 2015Assignee: GM Global Technology Operations, LLCInventors: Randal William Arndt, Douglas John Dwenger
-
Patent number: 8967353Abstract: A transmission includes a housing defining a sealed interior and an input hub rotatably coupled to the housing. A gear set is disposed within the housing and configured for receiving a torque from an engine. The transmission further includes an isolator assembly and a bypass clutch, each disposed within the sealed interior of the housing. The isolator assembly is configured for selectively damping drivetrain inertia and/or vibration. The bypass clutch selectively engages and disengages the isolator assembly.Type: GrantFiled: October 30, 2009Date of Patent: March 3, 2015Assignee: GM Global Technology Operations LLCInventors: Victor M. Roses, John A. Diemer, Randy Lewis Melanson, Douglas John Dwenger, Randal William Arndt, Pete R. Garcia, Michael L. Duhaime
-
Publication number: 20150024414Abstract: The present invention, in part, relates to methods and apparatuses for on-chip amplification and/or detection of various targets, including biological targets and any amplifiable targets. In some examples, the microculture apparatus includes a single-use, normally-closed fluidic valve that is initially maintained in the closed position by a valve element bonded to an adhesive coating. The valve is opened using a magnetic force. The valve element includes a magnetic material or metal. Such apparatuses and methods are useful for in-field or real-time detection of targets, especially in limited resource settings.Type: ApplicationFiled: January 16, 2014Publication date: January 22, 2015Applicant: Sandia CorporationInventors: Jason C. Harper, Thayne L. Edwards, Bryan Carson, Melissa Finley, William Arndt
-
Publication number: 20140318923Abstract: A torque transmitting device for use in an automotive transmission is provided. The device includes an inner annular race and an outer annular race disposed concentrically around the inner annular race. A selector plate is disposed adjacent to the inner and outer annular races, the selector plate being movable with respect to the inner and outer races. Multiple control elements are pivotally connected to the selector plate. The control elements are disposed between the inner and outer races. A plurality of sprag elements is disposed between the inner and outer races. Each sprag element is disposed adjacent to a control element.Type: ApplicationFiled: April 26, 2013Publication date: October 30, 2014Applicant: GM Global Technology Operations LLCInventors: Randal William Arndt, Douglas John Dwenger
-
Patent number: 8409050Abstract: A gear retention assembly for retaining a gear that has a plurality of gear outer splines includes a gear housing and a retaining ring. The gear housing has a first end, a second end, and a plurality of inner splines each including a ramp portion. The second end of the gear housing includes an annular continuous rolled lip, where the continuous rolled lip and the ramp portions of the plurality of inner splines define a groove. The plurality of inner splines engage with the gear outer splines of the gear to transmit torque between the gear and the gear housing. The retaining ring is disposed in the groove and axially retains the gear. The rolled lip axially retains the retaining ring.Type: GrantFiled: November 11, 2009Date of Patent: April 2, 2013Assignee: GM Global Technology Operations LLCInventors: Scott William Heitzenrater, Boris Burgman, Douglas John Dwenger, John A. Diemer, Randal William Arndt
-
Publication number: 20120076576Abstract: A retaining ring is characterized by a variable effective inner diameter and a variable effective outer diameter to axially retain a first member with respect to a second member.Type: ApplicationFiled: September 24, 2010Publication date: March 29, 2012Applicant: GM GLOBAL TECHNOLOGY OPERATIONS, INC.Inventors: Randy L. Melanson, Randal William Arndt
-
Publication number: 20110111917Abstract: A gear retention assembly for retaining a gear that has a plurality of gear outer splines includes a gear housing and a retaining ring. The gear housing has a first end, a second end, and a plurality of inner splines each including a ramp portion. The second end of the gear housing includes an annular continuous rolled lip, where the continuous rolled lip and the ramp portions of the plurality of inner splines define a groove. The plurality of inner splines engage with the gear outer splines of the gear to transmit torque between the gear and the gear housing. The retaining ring is disposed in the groove and axially retains the gear. The rolled lip axially retains the retaining ring.Type: ApplicationFiled: November 11, 2009Publication date: May 12, 2011Applicant: GM GLOBAL TECHNOLOGY OPERATIONS, INC.Inventors: Scott William Heitzenrater, Boris Burgman, Douglas John Dwenger, John A. Diemer, Randall William Arndt
-
Publication number: 20110100157Abstract: A transmission includes a housing defining a sealed interior and an input hub rotatably coupled to the housing. A gear set is disposed within the housing and configured for receiving a torque from an engine. The transmission further includes an isolator assembly and a bypass clutch, each disposed within the sealed interior of the housing. The isolator assembly is configured for selectively damping drivetrain inertia and/or vibration. The bypass clutch selectively engages and disengages the isolator assembly.Type: ApplicationFiled: October 30, 2009Publication date: May 5, 2011Applicant: GM GLOBAL TECHNOLOGY OPERATIONS, INC.Inventors: Victor M. Roses, John A. Diemer, Randy Lewis Melanson, Douglas John Dwenger, Randal William Arndt, Pete R. Garcia, Michael L. Duhaime
-
Publication number: 20080099540Abstract: A gum wrapper having two sheets of paper laminated with PLA resin material therebetween for packaging a plurality of wrapped, individual sticks of chewing gum.Type: ApplicationFiled: December 26, 2007Publication date: May 1, 2008Inventors: LouAnn Mueller, William Arndt
-
Publication number: 20060000735Abstract: A box for wrapped reams of copier, printer, or computer papers that provides more strength and protection for the reams inside.Type: ApplicationFiled: July 2, 2004Publication date: January 5, 2006Inventors: William Arndt, Wallace Maynard
-
Publication number: 20050148759Abstract: Ream wraps comprising PLA.Type: ApplicationFiled: January 13, 2005Publication date: July 7, 2005Inventors: LouAnn Mueller, William Arndt
-
Patent number: 5949550Abstract: A method and apparatus for detecting patches or areas of relatively high gloss on a moving web, and thereby associated wrinkles or other defects, and signalling the presence thereof comprises an analog and/or digital optical reflectivity sensor for sensing gloss on the surface of the moving web, a web marking device adjacent the edge of the moving web for marking the edge of the web with a dye, and a microcomputer for receiving the output signal from the sensor(s) and for controlling the operation of the marking device. The apparatus may also include a warning device such as a light or horn. The apparatus and method have particular applicability in association with paper web re-reeling equipment.Type: GrantFiled: August 21, 1997Date of Patent: September 7, 1999Assignee: Consolidated Papers, Inc.Inventors: William A. Arndt, Robert C. Cibuzar, Randall A. Freeh
-
Patent number: 5803222Abstract: A friction torque transmitting mechanism has a plurality of reaction plates interleaved with a plurality of friction drive plates. The reaction plates are brought into frictional contact with the drive plates by a fluid operated piston, such that a transfer of torque can be conducted through the frictional engagement of the plates. The reaction plates have a reaction portion disposed in a slot in a housing. One of the reaction plates has an axially extending reaction tab positioned between the reaction portions of the remaining plates and the sidewall of the slot. The reaction forces on the reaction portions are transmitted to the sidewall through the reaction tab.Type: GrantFiled: February 27, 1997Date of Patent: September 8, 1998Assignee: General Motors CorporationInventor: Randal William Arndt