Abstract: The present invention provides methods for preparing herbicide tolerant corn plants. Also provided are herbicide tolerant corn plants, as well as seeds and progeny derived from these plants.

Abstract: The present invention provides a method of killing replicating or non-replicating, transfected or transduced mammalian cells and bystander cells, comprising: (a) transfecting or transducing mammalian cells with a nucleic acid encoding a non-human purine cleavage enzyme; and (b) contacting the transfected or transduced cells with an effective amount of a substrate for the purine cleavage enzyme, wherein the substrate is non-toxic to mammalian cells and is cleaved by the enzyme to yield a purine toxic to the targeted mammalian cells and bystander cells, to kill the mammalian cells expressing the enzyme and the bystander cells. Further provided is a vector comprising a DNA sequence coding for a non-human purine nucleoside phosphorylase protein and the vector is capable of replication and/or expression in a host which comprises, in operable linkage: a) optionally, an origin of replication; b) a promoter; and c) a DNA sequence coding for said protein.

Abstract: Method for prophylaxis and treatment of a viral infection characterized by the administration of a composition comprising a substantial molar excess of the D-stereoisomer of 2'CdG over the L-stereoisomer.

Abstract: The invention provides a method of killing replicating or non-replicating, transfected or transduced mammalian cells and bystander cells, comprising the following steps: (a) transfecting or transducing mammalian cells with a nucleic acid encoding a non-human purine nucleoside phosphorylase (PNP); and (b) contacting the transfected or transduced cells with an amount of a substrate for the purine nucleoside phosphorylase sufficient to produce a toxic purine base-analog thereby killing the transfected or transduced cells and bystander cells. In the present method of killing cells, the non-human purine nucleoside phosphorylase can be an E. coli purine nucleoside phosphorylase. The method of the invention described above can utilize a substrate that is a purine nucleoside analog. For instance, in the method provided in the Examples, the substrate is 9-(.beta.-D-2-deoxyerythropentofuranosyl)-6-methylpurine (MeP-dR).

Abstract: Maize plants are grown in a planting area that are tolerant of inhibition by a cyclohexanedione herbicide, an aryloxyphenoxypropanoic acid herbicide, or mixtures thereof, at levels which normally inhibit growth and development, wherein said tolerance is conferred by an altered acetylcoenzyme A carboxylase (ACCase) tolerant of inhibition by the herbicide at levels which normally inhibit the activity of an unaltered ACCase. Additionally, an effective quantity of the named herbicide is applied so that the weeds (e.g., grass) are killed and the maize plants are uninjured. A representative cyclohexandione herbicide is sethoxydim and a representative aryloxyphenoxypropanoic acid herbicide is haloxyfop. Competition for the maize crop posed by weeds effectively is eliminated.

Abstract: The present invention provides a maize plant wherein the growth and development of said plant is tolerant of inhibition by a cyclohexanedione herbicide, an aryloxyphenoxypropanoic acid herbicide, or mixtures thereof, at levels which normally inhibit the growth and development of maize, wherein said tolerance is conferred by an altered acetyl coenzyme A carboxylase (ACCase) tolerant of inhibition by said herbicide at levels which normally inhibit the activity of an unaltered ACCase.

Abstract: The present invention provides a maize plant wherein the growth and development of said plant is tolerant of inhibition by a cyclohexanedione herbicide, an aryloxyphenoxypropanoic acid herbicide, or mixtures thereof, at levels which normally inhibit the growth and development of maize, wherein said tolerance is conferred by an altered acetyl coenzyme A carboxylase (ACCase) tolerant of inhibition by said herbicide at levels which normally inhibit the activity of an unaltered ACCase.

Abstract: A control apparatus for a filling machine of the type employing a hopper and rotary feed auger determines the exact number of auger revolutions required to deliver a preselected weight of material to be dispensed by weighing the volume of material delivered by a given number of auger revolutions and computing the ratio of the number of auger revolutions to the weight of the volume delivered. The ratio is then divided into the desired weight to determine the actual number of auger revolutions required to deliver the desired weight. The control apparatus also measures the amount of rotation of the rotary auger after the auger is braked at the end of each fill cycle and increments or decrements a preselected set point number of auger revolutions, depending upon whether the actual number of auger revolutions is greater than or less than the set point, to compensate for auger rotation after braking.