Abstract: A system includes a treatment cap assembly and a cooling and compression unit coupled to the treatment cap assembly. The treatment cap assembly comprises a fluid circulating pad configured to circulate a cooling fluid; and a compression hood configured to administer compression to a scalp of an individual wearing the treatment cap assembly. The cooling and compression unit is configured to provide the cooling fluid to the fluid circulating pad and to periodically provide compressed gas to the compression hood. The system can be used in a method that includes administering to an individual a dosage of a chemotherapeutic agent; cooling a scalp of the individual to a temperature of less than about 65° F.; and periodically administering compression to the scalp of the individual during the step of administering the dosage of the chemotherapeutic agent.

Abstract: Methods and related program product for assessing and optimizing metrology instruments by determining a total measurement uncertainty (TMU) based on precision and accuracy. The TMU is calculated based on a linear regression analysis and removing a reference measuring system uncertainty (URMS) from a net residual error. The TMU provides an objective and more accurate representation of whether a measurement system under test has an ability to sense true product variation. The invention also includes a method for determining an uncertainty of the TMU.