Abstract: The present invention includes a spray drying disposable device for use in a spray drying system. The disposable has a spray drying head and a plasma drying chamber. The head has a spray dry nozzle assembly in fluid communication with the plasma source and the pressurized aerosol gas source. The pressurized gas flows in a vortex pattern that atomizes plasma droplets in the chamber. The head also includes a plenum has uniform air pressure of the drying gas. A baffle plate forms the floor of the plenum having drying gas jets that supply drying gas to the chamber. The atomized plasma droplets evaporate in the presence of the drying gas emitted from the jets to obtain dried plasma particles and humid air. A capture filter captures the dried plasma particles and allows the humid air to pass. The humid air passes through the gas outlet and the exhaust port.

Abstract: The present invention includes a spray drying disposable device for use in a spray drying system. The disposable has a spray drying head and a plasma drying chamber. The head has a spray dry nozzle assembly in fluid communication with the plasma source and the pressurized aerosol gas source. The pressurized gas flows in a vortex pattern that atomizes plasma droplets in the chamber. The head also includes a plenum has uniform air pressure of the drying gas. A baffle plate forms the floor of the plenum having drying gas jets that supply drying gas to the chamber. The atomized plasma droplets evaporate in the presence of the drying gas emitted from the jets to obtain dried plasma particles and humid air. A capture filter captures the dried plasma particles and allows the humid air to pass. The humid air passes through the gas outlet and the exhaust port.

Abstract: The present invention includes an ease-of-use system that allows the spray drying disposable device to fit (e.g., align) in both spray drying apparatus and the spray drying finishing apparatus to safely operate the system. The system includes locating arrangements between the spray drying disposable and the spray drying apparatus and/or spray drying finishing apparatus, a first retainer and second retainer, a shorter disposable device that allows for effective spray drying of plasma, a feedback indicators of correct installment, redundant indicators of correct installment, easily accessible operator controls and emergency shut offs.

Abstract: The present invention relates to spray drying plasma methodology that includes pretreating a donated liquid plasma unit, drying the liquid plasma using a spray drying apparatus with the spray drying disposable device that results in a disposable having the dried plasma, finishing the disposable using the finishing apparatus that is designed to seal and separate the disposable, and transform the disposable into a dried plasma unit. The methods of the present invention include storing the dried plasma unit and, when ready for use, reconstituting the dried plasma unit with reconstitution solution to obtain a plasma unit ready for transfusion into a recipient.

Abstract: An alignment system that allows a spray drying disposable to align in both spray drying apparatus and finishing apparatus. The first instance is a locating arrangement wherein a locator is disposed on the spray drying apparatus and/or finishing apparatus and another locator is on the spray drying head of the disposable such that the locators allow for alignment of the disposable with the spray drying apparatus or finishing apparatus. A second instance of an alignment element includes a guide that is offset as positioned on the spray drying head of the disposable. Yet a third instance of the alignment arrangement relates to the gas exhaust port. In a fourth instance, the alignment system includes a positioning arrangement to reversibly attach the outer wall of the disposable to the finishing apparatus. In a fifth and sixth instance, a retaining device that retains the spray drying head in the spray drying apparatus and/or finishing apparatus.

Abstract: An example embodiment may involve receiving, from a client device, a request to access a web-based resource of a computational instance. The embodiment may also involve accessing data defining one or more change indications for one or more respective program code units, wherein each of the one or more change indications indicates that a respective program code unit of the one or more program code units has been changed since a most recent software release. The embodiment may also involve generating, for display via the client device, a representation of the web-based resource that includes a region specifying the one or more respective program code units for which there are change indications.

Abstract: The present invention includes a spray drying disposable device for use in a spray drying system. The disposable has a spray drying head and a plasma drying chamber. The head has a spray dry nozzle assembly in fluid communication with the plasma source and the pressurized aerosol gas source. The pressurized gas flows in a vortex pattern that atomizes plasma droplets in the chamber. The head also includes a plenum has uniform air pressure of the drying gas. A baffle plate forms the floor of the plenum having drying gas jets that supply drying gas to the chamber. The atomized plasma droplets evaporate in the presence of the drying gas emitted from the jets to obtain dried plasma particles and humid air. A capture filter captures the dried plasma particles and allows the humid air to pass. The humid air passes through the gas outlet and the exhaust port.

Abstract: The present invention includes a spray drying disposable device for use in a spray drying system. The disposable has a spray drying head and a plasma drying chamber. The head has a spray dry nozzle assembly in fluid communication with the plasma source and the pressurized aerosol gas source. The pressurized gas flows in a vortex pattern that atomizes plasma droplets in the chamber. The head also includes a plenum has uniform air pressure of the drying gas. A baffle plate forms the floor of the plenum having drying gas jets that supply drying gas to the chamber. The atomized plasma droplets evaporate in the presence of the drying gas emitted from the jets to obtain dried plasma particles and humid air. A capture filter captures the dried plasma particles and allows the humid air to pass. The humid air passes through the gas outlet and the exhaust port.

Abstract: A microelectromechanical system (MEMS) is comprised of a micromirror attached to a semiconductor device. A stack of inorganic high index materials comprised of titanium oxide, titanium nitride, and titanium is deposited above metal levels within the semiconductor device. Another stack of inorganic high index materials comprised of titanium oxide, titanium nitride, and titanium may be deposited in a continuous or dis-continuous layer within one or more of the dielectric layers. Each stack of high index material films is deposited at a depth and of thickness to achieve a minimum reflectance for the entire film system and to ensure maximum destructive interference at the targeted wavelength range. The high index material stack results in reduced light scattering during operation of the micromirror and improves contrast of the display system.

Abstract: A tubing shoe is disclosed with a body adapted to be connected to a section of tubing to be emplaced in a wellbore and a nose provided on the body, wherein the nose includes a failure guide structure for controlling break-up of the nose upon being drilled out from inside the nose. The failure guide structure typically controls break up by limiting the maximum size of pieces of the nose broken off upon drill out, for example, by defining weakened areas of the nose which are prone to failure upon drilling. The failure guide structure can include discontinuities such as slots or bores formed or drilled into the outer surface of the nose. The failure guide structure controls the break up of the nose in a consistent and predictable manner, and typically at a predictable stage during the drill-out process.

Abstract: A tubing shoe is disclosed with a body adapted to be connected to a section of tubing to be emplaced in a wellbore and a nose provided on the body, wherein the nose includes a failure guide structure for controlling break-up of the nose upon being drilled out from inside the nose. The failure guide structure typically controls break up by limiting the maximum size of pieces of the nose broken off upon drill out, for example, by defining weakened areas of the nose which are prone to failure upon drilling. The failure guide structure can include discontinuities such as slots or bores formed or drilled into the outer surface of the nose. The failure guide structure controls the break up of the nose in a consistent and predictable manner, and typically at a predictable stage during the drill-out process.

Abstract: An apparatus for controlling the flow of fluid into a borehole through a conduit has a decelerating means adapted to be positioned within the conduit. The fluid could typically comprise drilling mud and/or cement, and in some embodiments, some of the cement can exit through apertures in a shroud of the apparatus to cement the decelerating means inside the conduit.

Abstract: A centralizer having a body with an inner surface provided with a friction-reducing slider, typically located in an annular recess on the inner surface of the body of the slider, spaced from the ends of the body. The slider can be formed separately from a body of the centralizer and subsequently attached thereto on the inner surface so that it is adapted to bear between the outer surface of the tubing to be centralized and the inner surface of the centralizer. This reduces rotational torque transmitted between the centralizer and the tubing, and assists in maneuvering of the tubular string into the desired position in the well.

Abstract: A centraliser having a body with an inner surface provided with a friction-reducing slider, typically located in an annular recess on the inner surface of the body of the slider, spaced from the ends of the body. The slider can be formed separately from a body of the centraliser and subsequently attached thereto on the inner surface so that it is adapted to bear between the outer surface of the tubing to be centralised and the inner surface of the centraliser. This reduces rotational torque transmitted between the centraliser and the tubing, and assists in maneuvering of the tubular string into the desired position in the well.

Abstract: A catheter connection system is described herein, including a hub assembly and a connector assembly, the hub assembly including a cannula configured for insertion into a catheter lumen and the connector assembly including a collet and collar. The collet is connected to the hub assembly and positioned about a distal portion of the cannula such that an inner surface of the collet is spaced from an outer surface of the cannula. The collar and collet include features that interact with one another to provide a locking engagement. Also described is a multifunction adaptor to establish a connection between a catheter and another instrument, such as a tunneler or syringe.

Abstract: A propeller shaft bearing includes a substantially cylindrical sleeve having a structure including an inner layer and an outer layer that surrounds the inner layer. The inner layer is made of a bearing material that includes a thermosetting resin. The outer layer is made of a material that includes a thermosetting resin and has a lower swelling characteristic than the bearing material.

Abstract: Methods and apparatuses for facilitating removal of a catheter from a patient are provided. A catheter removal device is disclosed comprising a gripping mechanism with at least two members each member having a proximal end and distal end. The distal end of the gripping mechanism having opposing clamping members which, when closed, approximate at least a portion of the outer circumference of a catheter securement device. The proximal end of the gripping mechanism has two handle members each having a loop structure to accommodate the thumb or finger, for example, of a medical practitioner. A middle portion of the gripping mechanism has a shank member wherein the at least two members are coupled together at a pivot point. A distal end of the clamping members has a taper to allow for dilation of tissue up to the location of the catheter securement device.

Abstract: A catheter including a body defining a lumen and a valve including a perforation which forms a plurality of catheter valve surfaces. At least one coating may be substantially permanently adhered to at least a portion of at least one of the plurality of catheter surfaces. Also, a method of at least partially coating a catheter valve surface is disclosed. Further, the catheter valve may comprise a perforation which forms a plurality of catheter surfaces. At least one coating may be substantially permanently adhered to at least a portion of at least one of the plurality of catheter valve surfaces. An apparatus for at least partially opening a catheter valve is disclosed, including a tubular member including a bent region and an opening formed generally proximate the bent region structured to cause a catheter valve of a catheter to at least partially open.

Abstract: A medical device is disclosed comprising a diaphragm having at least one slit valve disposed therein, and a valve housing configured to secure the diaphragm at a peripheral portion of the diaphragm, wherein a central portion of the diaphragm is positioned relative to the peripheral portion of the diaphragm such that compressive forces acting on the peripheral portion of the diaphragm create moment forces which bias the slit valve in a closed position. A method is disclosed for using the device in connection with a catheter for regulation of fluids to and from a patient.

Abstract: A catheter connection system is disclosed. In one embodiment, a catheter connection system may include at least two components and a deformable sealing element positioned between the at least two components configured to allow, upon deformation, fluid flow through the at least two components. In another embodiment, the catheter connection system may include a sealing element positioned between at least two components, wherein the components are coupled to one another by a locking member.