Abstract: 2,4-diaminopyrimidine compounds of generic Formula 1, where R and R? may be the same or different and are independently selected from: C1-C6 alkyl or alkenyl groups with 1, 2, 3, 4, 5 or 6 carbon atoms, which may be: branched or unbranched; saturated or unsaturated; and may or may not be substituted, are used to treat anthrax.

Abstract: A method of treating an anthrax infection wherein a compound of formula I wherein R1 and R2 represent, independently of one another unsubstituted or specifically substituted C1-4alkoxy; and R3 represents hydrogen; cyano; unsubstituted or specifically substituted C1-6alkyl; C3-6cycloalkyl; C2-6alkenyl; C7-18bicyclyl; aryl, aryl-C1-4alkyl, aryl-Q-C1-4alkyl heteroaryl, heterocyclyl or heterocyclyl-C1-6alkyl, wherein aryl denotes a mono- or poly-nucleous group with 6 to 14 ring carbon atoms; heterocyclyl denotes a 4- to 6-membered non-aromatic heterocyclic group comprising 1 to 3, nitrogen, oxygen and/or sulfur atoms; heteroaryl denotes a mono- or polynuclear heteroaromatic group consisting 5- and/or 6-membered rings and comprising 5 to 13 carbon atoms and 1 to 4, nitrogen, oxygen and/or sulfur atoms; and Q means —SO— or —SO2—; or a pharmaceutically acceptable salt, solvate or hydrate or a prodrug thereof; is administered to said subject in a quantity effective to inhibit, suppress, or expel an anthrax inf

Abstract: A method of treating an anthrax infection wherein a compound of formula I wherein R1 and R2 represent, independently of one another unsubstituted or specifically substituted C1-4alkoxy; and R3 represents hydrogen; cyano; unsubstituted or specifically substituted C1-6alkyl; C3-6cycloalkyl; C2-6alkenyl; C7-18bicyclyl; aryl, aryl-C1-4alkyl, aryl-Q-C1-4alkyl heteroaryl, heterocyclyl or heterocyclyl-C1-6alkyl, wherein aryl denotes a mono- or poly-nucleous group with 6 to 14 ring carbon atoms; heterocyclyl denotes a 4- to 6-membered non-aromatic heterocyclic group comprising 1 to 3, nitrogen, oxygen and/or sulfur atoms; heteroaryl denotes a mono- or polynuclear heteroaromatic group consisting 5- and/or 6-membered rings and comprising 5 to 13 carbon atoms and 1 to 4, nitrogen, oxygen and/or sulfur atoms; and Q means —SO— or —SO2—; or a pharmaceutically acceptable salt, solvate or hydrate or a prodrug thereof; is administered to said subject in a quantity effective to inhibit, suppress, or expel an anthrax inf

Abstract: Systems and methods for atomic layer deposition (ALD) on a flexible substrate involve guiding the substrate back and forth between spaced-apart first and second precursor zones, so that the substrate transits through each of the precursor zones multiple times. Systems may include a series of turning guides, such as rollers, spaced apart along the precursor zones for supporting the substrate along an undulating transport path. As the substrate traverses back and forth between precursor zones, it passes through a series of flow-restricting passageways of an isolation zone into which an inert gas is injected to inhibit migration of precursor gases out of the precursor zones. Also disclosed are systems and methods for utilizing more than two precursor chemicals and for recycling precursor gases exhausted from the precursor zones.

Abstract: A tool for use in affixing an optical component, such as glass, to a liquid crystal display (LCD) using a silicone gel mixture of dimethyl siloxane and a vinyl terminated dimethyl polymer includes, in one embodiment, a unitary metallic platen that is shaped to define a central window. A narrow shelf is defined around the outer periphery of the central window, the shelf serving to support the optical component during the application of the silicone gel thereon. A upwardly extending partition is formed onto the top surface of the platen around the shelf, the partition serving, among other things, to retain the optical component fixed in place on the platen during the assembly process. A plurality of identical, spaced apart, upwardly extending standoffs are formed onto the free end of the partition and are designed to support the LCD a fixed distance away from the optical component.

Abstract: A method of monitoring a physical parameter comprises receiving a sensor signal representative of an actual value from each of a plurality of sensors. The method further comprises calculating confidence value for each sensed value and a weighted average of actual values of the sensor signal by weighting each sensed value by the respective confidence value. The weighted average is used to determine a corresponding value of the sensed parameter.

Abstract: Methods and apparatus for operating a gas turbine engine without sustained detrimental levels of dynamic pressure are provided. The engine includes a combustor. The method includes determining the combustor acoustic level amplitude, comparing the acoustic level to a predetermined upper acoustic limit, and adjusting a fuel flow distribution to the combustor using a closed loop controller to facilitate reducing the acoustic level to a predetermined lower acoustic limit that is less than the upper acoustic limit.