Abstract: The present invention relates to pharmaceutical compositions of an non-steroidal anti-inflammatory drug (NSAIDs) such as, aspirin, diclofenac, ibuprofen, ketoprofen, or naproxen, or any pharmaceutically acceptable salts, solvates, or prodrugs thereof, and the medical use of these compositions. The compositions, which can be formulated for topical administration, can provide extended release of the NSAIDs. The compositions of the invention are useful, for example, in the prophylactic treatment or treatment and/or reduction of pain, in the prophylactic treatment or treatment of headaches such as migraine headaches and symptoms of migraine headaches, and in the treatment of temporomandibular disorders (TMD).

Abstract: The present invention relates to pharmaceutical compositions of a non-steroidal anti-inflammatory drug (NSAIDs) such as, aspirin, diclofenac, ibuprofen, ketoprofen, or naproxen, or any pharmaceutically acceptable salts, solvates, or prodrugs thereof, and the medical use of these compositions. The compositions, which can be formulated for topical administration, can provide extended release of the NSAIDs. The compositions of the invention are useful, for example, in the prophylactic treatment or treatment and/or reduction of pain, in the prophylactic treatment or treatment of headaches such as migraine headaches and symptoms of migraine headaches, and in the treatment of temporomandibular disorders (TMD).

Abstract: A cargo management system includes a cargo anchor including a body extending between first and second ends and defining a hook profile along a first plane perpendicular to an axis extending between the first and second ends and a closed loop profile along a second plane parallel to the axis. The system further includes a substrate having an attachment feature with a first portion coupleable with the anchor profile and a second portion coupleable with the loop profile.

Abstract: The present invention relates to pharmaceutical compositions of a non-steroidal anti-inflammatory drug (NSAIDs) such as, aspirin, diclofenac, ibuprofen, ketoprofen, or naproxen, or any pharmaceutically acceptable salts, solvates, or prodrugs thereof, and the medical use of these compositions. The compositions, which can be formulated for topical administration, can provide extended release of the NSAIDs. The compositions of the invention are useful, for example, in the prophylactic treatment or treatment and/or reduction of pain, in the prophylactic treatment or treatment of headaches such as migraine headaches and symptoms of migraine headaches, and in the treatment of temporomandibular disorders (TMD).

Abstract: The present invention relates to pharmaceutical compositions of an non-steroidal anti-inflammatory drug (NSAIDs) such as, aspirin, diclofenac, ibuprofen, ketoprofen, or naproxen, or any pharmaceutically acceptable salts, solvates, or prodrugs thereof, and the medical use of these compositions. The compositions, which can be formulated for topical administration, can provide extended release of the NSAIDs. The compositions of the invention are useful, for example, in the prophylactic treatment or treatment and/or reduction of pain, in the prophylactic treatment or treatment of headaches such as migraine headaches and symptoms of migraine headaches, and in the treatment of temporomandibular disorders (TMD).

Abstract: A cargo management system includes a cargo anchor including a body extending between first and second ends and defining a hook profile along a first plane perpendicular to an axis extending between the first and second ends and a closed loop profile along a second plane parallel to the axis.

Abstract: A cargo management system for a vehicle includes a first pair, a second pair, and a third pair of anchors. The first and second pairs of anchors are positioned adjacent each other and the third pair of anchors is positioned remote from the first pair. The system further includes a flexible substrate having a first pair of attachment features coupleable with the first pair of anchors and a second pair of attachment features selectively coupleable with the second pair or third pair of anchors.

Abstract: A method of manufacturing a handle intended to be gripped by an occupant of a vehicle is shown to comprise the steps of selecting a substrate including a first part and a second part. The first part and second part are wrapped with a covering material that may be a premium material such as leather and may also include a layer of foam padding. The first part and second part are assembled together and attached to each other. After the two parts are wrapped, the first part and second part are assembled together and attached to each other. A line of stitches may be formed on the covering material before the wrapping step that are wrapped to be visible on the handle.

Abstract: A method of manufacturing a handle intended to be gripped by an occupant of a vehicle is shown to comprise the steps of selecting a substrate including a first part and a second part. The first part and second part are wrapped with a covering material that may be a premium material such as leather and may also include a layer of foam padding. The first part and second part are assembled together and attached to each other. After the two parts are wrapped, the first part and second part are assembled together and attached to each other. A line of stitches may be formed on the covering material before the wrapping step that are wrapped to be visible on the handle.

Abstract: A seatbelt assembly includes an adjuster having a guide slidable in a first direction. The assembly also includes a cover defining upper and lower edges and coupled with the guide and first and second extension plates slidably disposed relative to the cover in the first direction so as to be extendable respectively from the upper and lower edges thereof and to be retractable behind the cover.

Abstract: A cargo retention apparatus for a vehicle includes a vehicle panel defining an interior, an exterior, and an elongate slot open between the interior and exterior that extends in a first direction therealong. A track member is disposed on the interior of the panel and is aligned with the slot in the first direction. The apparatus further includes a hook having a base received through the slot and slidably coupled with the track member.

Abstract: A cargo management system for a vehicle includes a first pair, a second pair, and a third pair of anchors. The first and second pairs of anchors are positioned adjacent each other and the third pair of anchors is positioned remote from the first pair. The system further includes a flexible substrate having a first pair of attachment features coupleable with the first pair of anchors and a second pair of attachment features selectively coupleable with the second pair or third pair of anchors.

Abstract: A cargo retention apparatus for a vehicle includes a vehicle panel defining an interior, an exterior, and an elongate slot open between the interior and exterior that extends in a first direction therealong. A track member is disposed on the interior of the panel and is aligned with the slot in the first direction. The apparatus further includes a hook having a base received through the slot and slidably coupled with the track member.

Abstract: A seatbelt assembly includes an adjuster having a guide slidable in a first direction. The assembly also includes a cover defining upper and lower edges and coupled with the guide and first and second extension plates slidably disposed relative to the cover in the first direction so as to be extendable respectively from the upper and lower edges thereof and to be retractable behind the cover.

Abstract: A cowl trim assembly includes a panel body having front and side panel portions with anchor mechanism adapted to couple the trim assembly to a vehicle frame, and more specifically, to a vehicle door sill frame. A footrest assembly extends outwardly from the panel body having one or more reinforcement members disposed on an underside of the footrest assembly which are adapted to support the footrest assembly on a vehicle floor. In this configuration the footrest assembly is an integrated part of the cowl trim assembly, thereby providing a one-piece trim component having a self supporting footrest assembly, wherein the reinforcement members are adapted to carry loads applied to the footrest assembly by a vehicle occupant to the vehicle frame.

Abstract: A grab handle assembly for a vehicle has an asymmetrical handle that spans between a first end and a second end. The first end is operably coupled with an A-pillar of a frame of the vehicle. The second end is operably coupled with the A-pillar below the first end. The asymmetrical handle has a slanted portion and a curved portion, configured to provide a smooth downward transition between the A-pillar and the handle and to slidably deflect a forward moving object. The slanted portion extends down from the first end at a first angle. The curved portion protrudes outward and upward from the second end at a second angle to join the slanted portion. The first angle is less than the second angle and the first angle is less than thirty-five degrees, such that the first angle provides a smooth transition to the handle.

Abstract: A grab handle assembly for a vehicle has an asymmetrical handle that spans between a first end and a second end. The first end is operably coupled with an A-pillar of a frame of the vehicle. The second end is operably coupled with the A-pillar below the first end. The asymmetrical handle has a slanted portion and a curved portion, configured to provide a smooth downward transition between the A-pillar and the handle and to slidably deflect a forward moving object. The slanted portion extends down from the first end at a first angle. The curved portion protrudes outward and upward from the second end at a second angle to join the slanted portion. The first angle is less than the second angle and the first angle is less than thirty-five degrees, such that the first angle provides a smooth transition to the handle.

Abstract: A scuff plate assembly for use with an automotive vehicle door side sill includes an elongate scuff plate trim and a U-shaped wire shield for housing a wire harness. The scuff plate trim and wire shield are integrally coupled by a deformable living hinge that is disposed on an upper portion of the wire shield.

Abstract: A scuff plate assembly for use with an automotive vehicle door side sill includes an elongate scuff plate trim and a U-shaped wire shield for housing a wire harness. The scuff plate trim and wire shield are integrally coupled by a deformable living hinge that is disposed on an upper portion of the wire shield.

Abstract: An airbag ring for mounting an airbag assembly to an instrument panel including an airbag ring portion having a first aperture. The first aperture being dimensioned to allow an airbag to pass through the first aperture during airbag deployment and a duct mounting portion integral with the airbag ring portion, the duct mounting portion having a second aperture.