Patents by Inventor William Bess

William Bess has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Publication number: 20150238615
    Abstract: There are provided pharmaceutical compositions comprising a sympathomimetic amine, one or more amino polymers and one or more enteric polymeric compounds insoluble in water at pH below 5.5 the combination of which acts both to interfere with the isolation of the sympathomimetic amine from the composition and to interfere with the conversion of the sympathomimetic amine to another pharmacologically active compound, all of said components being well mixed with each other.
    Type: Application
    Filed: November 20, 2012
    Publication date: August 27, 2015
    Inventors: Leonard Mackles, William Bess
  • Publication number: 20140329779
    Abstract: The invention discloses a solid transparent vehicle utilizing DBS in which a topical pharmaceutical active or cosmetic active is solubilized without the use of a monohydric and/or polyhydric alcohol thus providing a non-tacky, clear solid, which prevents segregation and insures uniformity in dosing.
    Type: Application
    Filed: January 22, 2013
    Publication date: November 6, 2014
    Applicant: PRODUCT AND TECHNOLOGY PARTNERS LLC
    Inventors: Leonard Mackles, William Bess
  • Publication number: 20120240937
    Abstract: This invention relates to novel articles, particularly latex barrier articles, being coated with an antimicrobial coating useful to reduce the risk of cross-contamination and/or infection by harmful pathogenic microorganisms.
    Type: Application
    Filed: December 9, 2010
    Publication date: September 27, 2012
    Applicant: GlaxoSmithKline LLC
    Inventors: William Bess, Leonard Mackles
  • Publication number: 20120094882
    Abstract: There is provided a tasteless denture cleaning composition comprising inter alia, a source of hypochlorite, a source of sulfite and precipitated silica gel.
    Type: Application
    Filed: October 15, 2010
    Publication date: April 19, 2012
    Inventors: Leonard Mackles, William Bess
  • Patent number: 7741366
    Abstract: There is provided a new technology that will allow the formulation of pharmaceutically active organic acid products at relatively high pH during storage. This affords the advantages of avoiding formulation with the acid form of the product, yet when the product is used, the pH will be reduced via a chemical reaction, thus forming the organic acid which is the active form of the product. A by-product of the reaction is a significant increase in temperature, thus adding to the efficacy of the organic acid.
    Type: Grant
    Filed: January 24, 2007
    Date of Patent: June 22, 2010
    Inventors: Leonard Mackles, William Bess
  • Publication number: 20090176738
    Abstract: There is provided a means of applying a heated medicament to the skin and concurrently hydrating the skin thus raising the efficacy of administration.
    Type: Application
    Filed: December 9, 2008
    Publication date: July 9, 2009
    Inventors: Leonard Mackles, William Bess
  • Publication number: 20080089914
    Abstract: There is provided a new technology that will allow the formulation of pharmaceutically active organic acid products at relatively high pH during storage. This affords the advantages of avoiding formulation with the acid form of the product, yet when the product is used, the pH will be reduced via a chemical reaction, thus forming the organic acid which is the active form of the product. A by-product of the reaction is a significant increase in temperature, thus adding to the efficacy of the organic acid.
    Type: Application
    Filed: January 24, 2007
    Publication date: April 17, 2008
    Inventors: Leonard Mackles, Williams Bess
  • Publication number: 20070190089
    Abstract: This invention provides antiperspirants to combat axillary body odor by preventing or reducing perspiration, wherein the antiperspirant comprises a water-soluble ester to reduce the problems associated with stickiness and residue. The present invention provides a new class of detackifying agents that are easily formulated into clear, aqueous based antiperspirant formulations. These agents are readily water soluble, provide clear cosmetically elegant products and eliminate the stickiness and tackiness normally associated with aqueous based products.
    Type: Application
    Filed: February 2, 2007
    Publication date: August 16, 2007
    Inventors: Leonard Mackles, William Bess
  • Publication number: 20070166245
    Abstract: Propellant free foamable aqueous dentifrice system which is capable of being delivered as a foam to a toothbrush and which is stable on the brush and when placed in the mouth and used for tooth cleaning, continues to generate more foam. The system is liquid and as such can not be used without being foamed because it is so thin that it falls beneath the bristles of the toothbrush.
    Type: Application
    Filed: October 23, 2006
    Publication date: July 19, 2007
    Inventors: Leonard Mackles, William Bess
  • Publication number: 20060257499
    Abstract: There are provided vaginal rinse compositions, consisting essentially of: a) 1-20 wt % of a mucosally acceptable peroxide, b) 0.5-15 wt % of a mucosally acceptable sulfate, bisulfate, pyrosulfate salt of an inorganic cation or mixtures thereof, and c) water to 100 wt %. There are further provided methods of preparing and using said compositions as well as kits for maintaining the components to prepare said compositions.
    Type: Application
    Filed: June 8, 2006
    Publication date: November 16, 2006
    Inventors: Leonard Mackles, William Bess
  • Publication number: 20060216268
    Abstract: The instant invention makes impractical the use of sympathomimetic amine compositions in illicit drug production. More specifically, the preparation of methamphetamine from the disclosed pseudoephedrine hydrochloride formulations is inhibited. The present invention defines pharmaceutical compositions comprising a sympathomimetic amine salt and at least one combination inhibitor, the combination inhibitor which acts both to interfere with the isolation of the sympathomimetic amine from the composition and to interfere with the conversion of the sympathomimetic amine to another pharmacologically active compound. The contemplated compositions may also include reaction and separation inhibitors in any mixture to assure maximum protection against the use of the sympathomimetic amine-containing compositions for illegal drug manufacture. The presence of the combination, reaction and separation inhibitors does not significantly alter the release of the sympathomimetic amine from the composition.
    Type: Application
    Filed: June 2, 2006
    Publication date: September 28, 2006
    Inventors: William Bess, William Nichols
  • Publication number: 20060204559
    Abstract: Physiologically acceptable films, including edible films, are disclosed. The films include a water soluble film-forming polymer, such as pullulan, and a taste masked pharmaceutically active agent, such as dextromethorphan. The taste masking agent is preferably a sulfonated polymer ion exchange resin comprising polystyrene cross-linked with divinylbenzene, such as AMBERLITE. Methods for producing the films are also disclosed.
    Type: Application
    Filed: May 5, 2006
    Publication date: September 14, 2006
    Inventors: William Bess, Neema Kulkarni, Suhas Ambike, Michael Ramsay
  • Publication number: 20060134021
    Abstract: There are provided oral mouth rinse compositions, consisting essentially of: a) 1-20 wt % of an orally acceptable peroxide, b) 0.5-15 wt % of an orally acceptable sulfate, bisulfate, pyrosulfate salt of an inorganic cation or mixtures thereof, and c) water to 100 wt %. There are further provided methods of preparing and using said compositions as well as kits for maintaining the components to prepare said compositions.
    Type: Application
    Filed: December 22, 2004
    Publication date: June 22, 2006
    Inventors: Leonard Mackles, William Bess
  • Publication number: 20060134022
    Abstract: Effective stimulation of oral salivary activity in the oral cavity is achieved by the introduction thereinto of a warm aqueous solution, containing 0.5-15 wt % of an inorganic cation salt of a sulfate, bisulfate pyrosulfate or mixture thereof, having a temperature of at least 103° F. (39.4° C.).
    Type: Application
    Filed: October 21, 2005
    Publication date: June 22, 2006
    Inventors: Leonard Mackles, William Bess
  • Publication number: 20050256194
    Abstract: The instant invention makes impractical the use of sympathomimetic amine compositions in illicit drug production. More specifically, the preparation of methamphetamine from the disclosed pseudoephedrine hydrochloride formulations is inhibited. The present invention defines pharmaceutical compositions comprising a sympathomimetic amine salt and at least one combination inhibitor, the combination inhibitor which acts both to interfere with the isolation of the sympathomimetic amine from the composition and to interfere with the conversion of the sympathomimetic amine to another pharmacologically active compound. The contemplated compositions may also include reaction and separation inhibitors in any mixture to assure maximum protection against the use of the sympathomimetic amine-containing compositions for illegal drug manufacture. The presence of the combination, reaction and separation inhibitors does not significantly alter the release of the sympathomimetic amine from the composition.
    Type: Application
    Filed: July 20, 2005
    Publication date: November 17, 2005
    Inventors: William Bess, William Nichols
  • Publication number: 20050230871
    Abstract: The present invention relates to consumable film products and a method for producing same. More particularly, one aspect of the invention provides a method of making a consumable film by forming a composition into a ribbon, feeding the ribbon to one or more dies, cutting the ribbon into sections, and drying the sections. One or more ribbons may be simultaneously treated. The dies of the invention may be configured to produce an array of variously shaped products having a thickness of less than about ??. Another aspect of the invention provides single-layer films and multiple-layer films produced according to the disclosed methods.
    Type: Application
    Filed: April 20, 2005
    Publication date: October 20, 2005
    Inventor: William Bess
  • Patent number: 6245785
    Abstract: The present invention is directed to pharmaceutical compositions containing triprolidine and an ionic additive that improves the measured availability of the triprolidine in the tablet, as indicated by standard USP assay for triprolidine in pharmaceutical compositions. The invention also provides a process for producing compositions having improved triprolidine availability and a process for improving the performance of a pharmaceutical composition in a dissolution assay measuring triprolidine availability. The ionic additive can be, for example, an alkali metal salt, such as sodium chloride or potassium chloride.
    Type: Grant
    Filed: November 30, 1998
    Date of Patent: June 12, 2001
    Assignee: Warner Lambert Company
    Inventors: Victor A. Cruz, W. Michael Nichols, Albert F. Sorg, George E. Tortarolo, William Bess, Neema Kulkarni
  • Patent number: 6136864
    Abstract: A pharmaceutical composition has an acid salt of a sympathomimetic amine; and a denaturant of (i) at least one gum or viscosity modifier, and (ii) at least one surfactant, wherein the gum or viscosity modifier and the surfactant are present in amounts sufficient to have a denaturing effect on the sympathomimetic amine without significantly compromising the release of the sympathomimetic amine from the composition.
    Type: Grant
    Filed: September 25, 1997
    Date of Patent: October 24, 2000
    Assignee: Warner-Lambert Company
    Inventors: W. Michael Nichols, William Bess, Stanley Lech
  • Patent number: 3998761
    Abstract: Shampoo compositions capable of conditioning hair containing relatively high quantities of beer solids as hair conditioning agents.
    Type: Grant
    Filed: April 17, 1975
    Date of Patent: December 21, 1976
    Assignee: Bristol-Myers Company
    Inventors: Herbert H. Gary, William Bess, Frederick Hubner