Abstract: The present disclosure relates to heterocyclic compounds, pharmaceutically acceptable salts thereof, and pharmaceutical preparations thereof. Also described herein are compositions and the use of such compounds in methods of treating diseases and conditions mediated by deficient CFTR activity, in particular cystic fibrosis.

Abstract: The present disclosure relates to heterocyclic compounds, pharmaceutically acceptable salts thereof, and pharmaceutical preparations thereof. Also described herein are compositions and the use of such compounds in methods of treating diseases and conditions mediated by deficient CFTR activity, in particular cystic fibrosis.

Abstract: A method, system, computer program product and apparatus related to managing and disseminating information in a health care facility is disclosed. The system may comprise a plurality of input devices, a processor connected to the input devices and a plurality of electronic output devices connected to the processor. The output devices may include a master patient information display, an electronic patient room information display, a master precaution display, a patient hourly rounding display and an individual room precaution display. The method may comprises receiving from at least one input device data associated with a plurality of patients, and displaying for each patient the information, based on the data received, that is associated with each patient, and then updating on each output device the information when it changes.

Abstract: A method, system, computer program product and apparatus related to managing and disseminating information in a health care facility is disclosed. The system may comprise a plurality of input devices, a processor connected to the input devices and a plurality of electronic output devices connected to the processor. The output devices may include a master patient information display, an electronic patient room information display, a master precaution display, a patient hourly rounding display and an individual room precaution display. The method may comprises receiving from at least one input device data associated with a plurality of patients, and displaying for each patient the information, based on the data received, that is associated with each patient, and then updating on each output device the information when it changes.

Abstract: The invention relates to compounds of the formula I in which R1, R2, X, A, B, Z and Y1 to Y4 have the meanings indicated in the claims, and/or a pharmaceutically acceptable salt and/or a prodrug thereof. Because of their properties as inhibitors of chemokine receptors, especially as CXCR2 inhibitors, the compounds of the formula I and the pharmaceutically acceptable salts and prodrugs thereof are suitable for the prevention and treatment of chemokine mediated diseases.

Abstract: A method, system, computer program product and apparatus related to managing and disseminating information in a health care facility is disclosed. The system may comprise a plurality of input devices, a processor connected to the input devices and a plurality of electronic output devices connected to the processor. The output devices may include a master patient information display, an electronic patient room information display, a master precaution display, a patient hourly rounding display and an individual room precaution display. The method may comprise receiving from at least one input device data associated with a plurality of patients, and displaying for each patient the information, based on the data received, that is associated with each patient, and then updating on each output device the information when it changes.

Abstract: The invention relates to compounds of the formula I in which R1, R2, X, A, B, Z and Y1 to Y4 have the meanings indicated in the claims, and/or a pharmaceutically acceptable salt and/or a prodrug thereof. Because of their properties as inhibitors of chemokine receptors, especially as CXCR2 inhibitors, the compounds of the formula I and the pharmaceutically acceptable salts and prodrugs thereof are suitable for the prevention and treatment of chemokine mediated diseases.