Abstract: The present application provides, in some aspects, methods of identifying a condensate of interest associated with a el disease. Also provided are methods of identifying a marker for identifying a condensate of interest associated with a disease. In other aspects, provided herein are methods of identifying a therapeutic agent useful for treating a disease via the identified condensate of interest.

Abstract: A system, method, and computer program product for providing a resilient network-to-network interface (RNNI) between a first frame relay network and a second frame relay network. The RNNI comprises a plurality of data links that connect a master node in the first network to a slave node in the second network. The RNNI is initialized by operating an independent instance of a Link Integrity Verification (LIV) routine on each of the data links, returning an UP or DOWN status. One of the data links is designated as the ACTIVE data link, and the remaining data links are designated as INACTIVE. Once the RNNI is initialized, the ACTIVE data link is monitored using RNNI link management procedures including the LIV routine and a Permanent Virtual Circuit (PVC) polling routine, and the INACTIVE data links are monitored using the LIV routine.