Patents by Inventor William C. Patt

William C. Patt has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Substituted derivatives of 3-amino-2-hydroxypropionic acid as inhibitors of renin
    Patent number: 5135914
    Abstract: Novel substituted derivatives of 3-amino-2-hydroxypropionic acid are described, as well as methods for the preparation and pharmaceutical compositions of same, which are useful as renin inhibitors and thus useful in controlling hypertension, hyperaldosteronism and congestive heart failure as well as diagnostic agents.
    Type: Grant
    Filed: May 23, 1988
    Date of Patent: August 4, 1992
    Assignee: Warner-Lambert Company
    Inventors: Harriet W. Hamilton, William C. Patt
  • Diol-containing renin inhibitors
    Patent number: 5036053
    Abstract: The invention concerns novel renin-inhibitory peptides which are useful for treating renin-associated hypertension, congestive heart failure, hyperaldosteronism, and diseases caused by retroviruses including HTLV-I and -III. Processes for preparing the peptides, composition containing them, and methods of using them are included. Also included is a diagnostic method which uses the compounds to determine the presence of renin-associated hypertensions, or hyperaldosteronism.
    Type: Grant
    Filed: March 15, 1989
    Date of Patent: July 30, 1991
    Assignee: Warner-Lambert Company
    Inventors: Richard Himmelsbach, John C. Hodges, James S. Kaltenbronn, William C. Patt, Joseph T. Repine, Ila Sircar
  • Method of treating psychosis using N.sup.6 -substituted -5'-oxidized adenosine analogs
    Patent number: 4868160
    Abstract: Novel N.sup.6 -substituted-5'-oxidized adenosine analogs, and pharmaceutical compositions, methods of use or processes to make therefor. The novel adenosines have utility for the treatment of hypertension, coronary insufficiency, psychosis, pain, angina, and heart failure.
    Type: Grant
    Filed: December 31, 1987
    Date of Patent: September 19, 1989
    Assignee: Warner-Lambert Company
    Inventors: Harriet W. Hamilton, William C. Patt
  • 2,N.sup.6 -disubstituted adenosines, derivatives and methods of use
    Patent number: 4791103
    Abstract: Novel N.sup.6 -substituted adenosines having desirable ratio of affinities at A1 or A2 receptors and highly desirable central nervous system and cardiovascular activities, such as analgesic, antipsychotic, sedative, or antihypertensive as well as immunoinflammatory activity.
    Type: Grant
    Filed: September 5, 1985
    Date of Patent: December 13, 1988
    Assignee: Warner-Lambert Company
    Inventors: Bharat K. Trivedi, Walter Moos, Harriet W. Hamilton, William C. Patt
  • Novel N.sup.6 -substituted-5'-oxidized adenosine analogs
    Patent number: 4738954
    Abstract: Novel N.sup.6 -substituted-5'-oxidized adenosine analogs, and pharmaceutical compositions, methods of use or processes to make therefore. The novel adenosines have utility for the treatment of hypertension, coronary insufficiency, psychosis, pain, angina, and heart failure.
    Type: Grant
    Filed: November 6, 1985
    Date of Patent: April 19, 1988
    Assignee: Warner-Lambert Company
    Inventors: Harriet W. Hamilton, William C. Patt
  • N.sup.6 -acenaphthyl adenosines and analogs thereof
    Patent number: 4673670
    Abstract: N.sup.6 -Acenaphthyl adenosines and analogs thereof and pharmaceutically acceptable acid addition salts having highly desirable blood pressure lowering properties, processes for their manufacture and pharmaceutical compositions and methods for using said compounds and compositions are described.
    Type: Grant
    Filed: April 30, 1986
    Date of Patent: June 16, 1987
    Assignee: Warner-Lambert Company
    Inventors: Harriet W. Hamilton, William C. Patt, Bharat K. Trivedi
  • N.sup.6 -dihydroxypropyladenosines
    Patent number: 4616003
    Abstract: N.sup.6 -Dihydroxypropyladenosines and pharmaceutically acceptable acid addition salts having highly desirable central nervous system properties, processes for their manufacture and pharmaceutical compositions and methods for using said compounds and compositions are described.
    Type: Grant
    Filed: September 5, 1985
    Date of Patent: October 7, 1986
    Assignee: Warner-Lambert Company
    Inventors: Harriet W. Hamilton, William C. Patt
  • N.sup.6 -acenaphthyl adenosines and analogs thereof
    Patent number: 4614732
    Abstract: N.sup.6 -acenaphthyl adenosines and analogs thereof and pharmaceutically acceptable acid addition salts having highly desirable blood pressure lowering properties, processes for their manufacture and pharmaceutical compositions and methods for using said compounds and compositions are described.
    Type: Grant
    Filed: September 5, 1985
    Date of Patent: September 30, 1986
    Assignee: Warner-Lambert Company
    Inventors: Harriet W. Hamilton, William C. Patt, Bharat K. Trivedi