Patents by Inventor William C. Pomerantz

William C. Pomerantz has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Beta-peptides with antifungal activity
    Patent number: 9168329
    Abstract: The present invention is directed to the design, synthesis and use of various ?-peptides exhibiting antifungal activity. The ?-peptides are relatively short in length, adopt globally amphiphilic conformations, and cause little lysis of human red blood cells at concentrations that kill Candida albicans, a common human fungal pathogen.
    Type: Grant
    Filed: September 4, 2007
    Date of Patent: October 27, 2015
    Assignee: Wisconsin Alumni Research Foundation
    Inventors: Sean P. Palecek, Samuel H. Gellman, William C. Pomerantz, Amy J. Karlsson
  • ?-peptide lyotropic liquid crystals and methods of manufacture and use thereof
    Patent number: 8021570
    Abstract: The present invention provides materials and methods that make liquid crystal phases accessible with relatively short ?-peptides in aqueous solvents.
    Type: Grant
    Filed: June 13, 2007
    Date of Patent: September 20, 2011
    Assignee: Wisconsin Alumni Research Foundation
    Inventors: Samuel H. Gellman, Nicholas L. Abbott, William C. Pomerantz
  • Concise ?-amino acid synthesis via organocatalytic aminomethylation
    Patent number: 7820858
    Abstract: The present invention provides a method for the synthesis of ?2-amino acids. The method also provides methods yielding ?-substituted ?-amino aldehydes and ?-substituted ?-amino alcohols. The present method according to this invention allows for increased yield and easier purification using minimal chromatography or crystallization. The methods described herein are based on an aldehyde aminomethylation which involves a Mannich reaction between an aldehyde and a formaldehyde-derived N,O-acetal (iminium precursor) and a catalyst, such as, for example, L-proline or a pyrrolidine. The invention allows for large scale, commercial preparation of ?2-amino acids.
    Type: Grant
    Filed: March 26, 2007
    Date of Patent: October 26, 2010
    Assignee: Wisconsin Alumni Research Foundation
    Inventors: Yonggui Chi, Samuel H. Gellman, William C. Pomerantz, William S. Horne, Li Guo, Emily P. English
  • BETA-PEPTIDE LYOTROPIC LIQUID CRYSTALS AND METHODS OF MANUFACTURE AND USE THEREOF
    Publication number: 20100021344
    Abstract: The present invention provides materials and methods that make liquid crystal phases accessible with relatively short ?-peptides in aqueous solvents.
    Type: Application
    Filed: June 13, 2007
    Publication date: January 28, 2010
    Applicant: WISCONSIN ALUMNI RESEARCH FOUNDATION
    Inventors: Samuel H. GELLMAN, Nicholas L. ABBOTT, William C. POMERANTZ
  • BETA-PEPTIDES WITH ANTIFUNGAL ACTIVITY
    Publication number: 20080166388
    Abstract: The present invention is directed to the design, synthesis and use of various ?-peptides exhibiting antifungal activity. The ?-peptides are relatively short in length, adopt globally amphiphilic conformations, and cause little lysis of human red blood cells at concentrations that kill Candida albicans, a common human fungal pathogen.
    Type: Application
    Filed: September 4, 2007
    Publication date: July 10, 2008
    Applicant: Wisconsin Alumni Research Foundation
    Inventors: Sean P. Palecek, Samuel H. Gellman, William C. Pomerantz