Patents by Inventor William C. Thomas, Jr.

William C. Thomas, Jr. has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Method for complexing a free metal ion
    Patent number: 5719138
    Abstract: The metal ion complexing properties exhibited by dicitrate are disclosed as chelating agents for reducing the amounts of metal ions in a substance.
    Type: Grant
    Filed: June 2, 1995
    Date of Patent: February 17, 1998
    Assignee: University of Florida
    Inventors: William C. Thomas, Jr., Christopher D. Batich, Daniel L. Purich
  • Clinical marker and therapeutic agent in kidney stone disease and methods of use
    Patent number: 5607964
    Abstract: Treating patients prophylactically and therapeutically with dicitrate cyclic diester (dicitrate) can prevent or reduce the effects of calcification-related disease, including some types of kidney stones.
    Type: Grant
    Filed: June 2, 1995
    Date of Patent: March 4, 1997
    Assignee: University of Florida
    Inventors: William C. Thomas, Jr., Christopher D. Batich, Daniel L. Purich
  • Kit for detection of clinical marker in kidney stone disease
    Patent number: 5604103
    Abstract: Dicitrate cyclic diester (dicitrate) is a novel compound which is found in patients who do not exhibit symptoms or predisposition to idiopathic renal calculous disease. Kits are provided for the detection of dicitrate cyclic diester.
    Type: Grant
    Filed: June 17, 1994
    Date of Patent: February 18, 1997
    Assignee: University of Florida
    Inventors: William C. Thomas, Jr., Christopher D. Batich, Daniel L. Purich
  • Dicitrate cyclic diester dentifrice
    Patent number: 5601804
    Abstract: Dicitrate cyclic diester (dicitrate) is a novel compound which is found in patients who do not exhibit symptoms or predisposition to idiopathic renal calculous disease. Dicitrate can be isolated and detected by novel chromatographic methods. Further, treating patients prophylactically and therapeutically with dicitrate cyclic diester can prevent or reduce the effects of calcification-related disease, including some types of kidney stones, or other disease or condition associated with the presence of metal ions. The metal ion complexing properties exhibited by dicitrate are also applicable to the use of the subject compounds as chelating agents and methods of binding, and thereby reducing, the amounts of metal ions in a substance.
    Type: Grant
    Filed: June 2, 1995
    Date of Patent: February 11, 1997
    Assignee: The University of Florida
    Inventors: William C. Thomas, Jr., Christopher D. Batich, Daniel L. Purich
  • Clinical marker and therapeutic agent in kidney stone disease and methods of use
    Patent number: 5550259
    Abstract: Dicitrate cyclic diester (dicitrate) is a novel compound which is found in patients who do not exhibit symptoms or predisposition to idiopathic renal calculous disease. Dicitrate can be isolated and detected by novel chromatographic methods. Further, treating patients prophylactically and therapeutically with dicitrate cyclic diester can prevent or reduce the effects of calcification-related disease, including some types of kidney stones, or other disease or condition associated with the presence of metal ions. The metal ion complexing properties exhibited by dicitrate are also applicable to the use of the subject compounds as chelating agents and methods of binding, and thereby reducing, the amounts of metal ions in a substance.
    Type: Grant
    Filed: June 2, 1995
    Date of Patent: August 27, 1996
    Assignee: The University of Florida
    Inventors: William C. Thomas, Jr., Christopher D. Batich, Daniel L. Purich
  • Clinical marker and therapeutic agent in kidney stone disease and methods of use
    Patent number: 5376553
    Abstract: Dicitrate cyclic diester (dicitrate) is a novel compound which is found in patients who do not exhibit symptoms or predisposition to idiopathic renal calculous disease. Dicitrate can be isolated and detected by novel chromatographic methods. Further, treating patients prophylactically and therapeutically with dicitrate cyclic diester can prevent or reduce the effects of calcification-related disease, including some types of kidney stones.
    Type: Grant
    Filed: June 18, 1993
    Date of Patent: December 27, 1994
    Assignee: University of Florida
    Inventors: William C. Thomas, Jr., Christopher D. Batich, Daniel L. Purich