Abstract: A diffusion rate limiting matrix is utilized to buccally, lingually and/or sublingually deliver thioctic acid. This limited release matrix is intended for general nutritional supplementation and/or the treatment of various physiological disorders. Due to its lingual nature, this rate limiting matrix can deliver approximately IV-equivalent plasma levels of thioctic acid and is not meant to be swallowed.

Abstract: A diffusion rate limiting matrix is utilized to lingually and/or sublingually deliver thioctic acid. This limited release matrix is intended for general nutritional supplementation and/or the treatment of various physiological disorders. Due to its lingual nature, this rate limiting matrix can produce IV-equivalent plasma levels and is not meant to be swallowed.

Abstract: The mid-zone pressing tool has a base and a pressing assembly, which are pivotally connected at the rear by a transverse shaft. A pair of cantilevers extends forward from each side of an uppermost rear portion of the base. A pair of arms is connected on the distal ends by a common handle. A first coupling connects a middle portion of each arm to the pressing assembly by an axle, cam or link. A second coupling connects the proximal ends of each arm to the cantilever by an axle, cam or link. Pushing the handle down pivots the arms, engages the couplings, and transmits a concentrated downward force to the front of the pressing assembly. The cantilevers allow a range of coupling placements, including near the middle of the pressing tool. The couplings are optionally releasable.

Abstract: The mid-zone pressing tool has a base and a pressing assembly, which are pivotally connected at the rear by a transverse shaft. A pair of cantilevers extends forward from each side of an uppermost rear portion of the base. A pair of arms is connected on the distal ends by a common handle. A first coupling connects a middle portion of each arm to the pressing assembly by an axle, cam or link. A second coupling connects the proximal ends of each arm to the cantilever by an axle, cam or link. Pushing the handle down pivots the arms, engages the couplings, and transmits a concentrated downward force to the front of the pressing assembly. The cantilevers allow a range of coupling placements, including near the middle of the pressing tool. The couplings are optionally releasable.