Abstract: An electronic device can implement a zero-latency digital assistant by capturing audio input from a microphone and using a first processor to write audio data representing the captured audio input to a memory buffer. In response to detecting a user input while capturing the audio input, the device can determine whether the user input meets a predetermined criteria. If the user input meets the criteria, the device can use a second processor to identify and execute a task based on at least a portion of the contents of the memory buffer.

Abstract: A method and apparatus for transmitting data using moving communication nodes. A network element can communicate with a plurality of moving communication simultaneously. The network element identifies a plurality of potential initial nodes for transmitting data to a desired destination. The network element can then evaluate each of the potential initial nodes using one or more selection criteria. The initial node can be selected from the plurality of potential initial nodes as the potential initial node that best satisfies the selection criteria. The transmission to the initial node can act as the first link in a data route from the network element to the desired geographic destination.

Abstract: The present invention provides a method and apparatus used to reduce the estimated field of uncertainty of satellite positions in space. This reduced field of uncertainty estimate reduces link acquisition time of satellites as they establish inter-satellite optical links between each other. The method and apparatus reduces the estimated field of uncertainty by combining estimated field of uncertainty generated by multiple independent sources. The method further includes combining estimated field of uncertainty generated using existing field of uncertainty techniques with estimated filed of uncertainty created by a machine vision detection and location module. This machine vision detection and location module generates an estimated field of uncertainty that is a result of executing of one or more algorithms to process digital imagery data provided by a passive digital camera.

Abstract: A method for configuring a communication network, including obtaining information indicative of current status of nodes of the communication network, links between said nodes of the communication network or a combination thereof; processing the information to determine a network configuration based on the obtained information, the network configuration implementable in the communication network by adjusting one or more of said nodes, one of more of said links between said node, or a combination thereof, wherein said processing comprises evaluating at least the network configuration based on a connectivity metric indicative of an extent to which said nodes are interconnected via said links; and providing instructions directing one or more underlying resources to implement the network configuration.

Abstract: A method and apparatus for configuring a communication network based on a distance metric. Information indicative of current status of communication network nodes, links between the nodes, or a combination thereof is obtained and processed to determine a network configuration. The network configuration is implementable in the communication network by adjusting one or more nodes or links. The processing includes evaluating network configurations based on a distance metric, which is indicative of lengths of shortest paths which interconnect nodes of the network. Instructions directing underlying resources to implement the network configuration can be provided. An apparatus can be a supervisory device including a network interface and a computer processor.

Abstract: A method and apparatus for transmitting data using moving communication nodes. A network element can communicate with a plurality of moving communication simultaneously. The network element identifies a plurality of potential initial nodes for transmitting data to a desired destination. The network element can then evaluate each of the potential initial nodes using one or more selection criteria. The initial node can be selected from the plurality of potential initial nodes as the potential initial node that best satisfies the selection criteria. The transmission to the initial node can act as the first link in a data route from the network element to the desired geographic destination.

Abstract: A method and apparatus for configuring a communication network based on a distance metric. Information indicative of current status of communication network nodes, links between the nodes, or a combination thereof is obtained and processed to determine a network configuration. The network configuration is implementable in the communication network by adjusting one or more nodes or links. The processing includes evaluating network configurations based on a distance metric, which is indicative of lengths of shortest paths which interconnect nodes of the network. Instructions directing underlying resources to implement the network configuration can be provided. An apparatus can be a supervisory device including a network interface and a computer processor.

Abstract: The present invention provides a method and apparatus for supporting estimation of inter-satellite link acquisition times in a satellite constellation. The method includes computing or generating an indication of a statistical model based on observations for prior link acquisition times. The method further includes communicating an indication such as a statistical model for link acquisition times or related parameters through a communication network, or a combination thereof. The indication may be communicated using one or more transmission techniques or protocols, such as flooding, a link state protocol or gossip protocol. Based on the disseminated indication, future link acquisition times can be predicted by satellites in the satellite constellation. Embodiments of the invention use a statistical-based computation approach, such as regression modelling or random variable modelling, to estimate link acquisition times or associated estimation parameters.

Abstract: A method for configuring a communication network, including obtaining information indicative of current status of nodes of the communication network, links between said nodes of the communication network or a combination thereof; processing the information to determine a network configuration based on the obtained information, the network configuration implementable in the communication network by adjusting one or more of said nodes, one of more of said links between said node, or a combination thereof, wherein said processing comprises evaluating at least the network configuration based on a connectivity metric indicative of an extent to which said nodes are interconnected via said links; and providing instructions directing one or more underlying resources to implement the network configuration.

Abstract: The present invention is provides a method and apparatus for routing a data packet in a network. For each nearby device capable of routing the packet toward a further destination, an associated cost or utility is determined. The device with lowest cost or highest utility is selected and the packet is forwarded toward same. The selecting may use a comparator tree. The cost or utility may be associated with forwarding the data packet from the candidate device toward the further destination. The cost or utility may be based on a distance from candidate device to the further destination, and may be determined using a Haversine function or approximation thereof, or by computing an inner product of a first vector and a second vector originating at a center of Earth, the first vector directed toward the candidate device, the second vector directed toward the further destination.

Abstract: A method and apparatus for routing packets in a network, such as a satellite mesh network. For each one of multiple destination devices capable of further handling of the packet for routing to a destination (e.g. ground station) a respective cost or utility associated with forwarding the packet to that destination device is determined. For a given value k, an unsorted subset of k of the destination devices for which said costs are lowest or said utilities are highest is determined, without necessarily fully sorting the plurality of destination devices by cost or utility. The data packet is then forwarded to a selected one of this subset of destination devices. Cost may correspond to distance from destination device (e.g. satellite) to the further destination. Sorting networks and selector networks can be used, for example as implemented in hardware, to generate the unsorted subset.

Abstract: The present invention provides a method and apparatus used to reduce the estimated field of uncertainty of satellite positions in space. This reduced field of uncertainty estimate reduces link acquisition time of satellites as they establish inter-satellite optical links between each other. The method and apparatus reduces the estimated field of uncertainty by combining estimated field of uncertainty generated by multiple independent sources. The method further includes combining estimated field of uncertainty generated using existing field of uncertainty techniques with estimated filed of uncertainty created by a machine vision detection and location module. This machine vision detection and location module generates an estimated field of uncertainty that is a result of executing of one or more algorithms to process digital imagery data provided by a passive digital camera.

Abstract: Disclosed herein is a method of “reprogramming” highly motile cells found in tumors, such as these highly motile GSC and/or MDSC clones, into “auto-destructive” cell “missiles” (referred to herein as therapeutic stealth cells) that can seek and destroy new foci of recurrence within the body, such as the brain. Cells with enhanced motility can be sorted out from heterogeneous populations and then be rendered “auto-destructive” by deterministic delivery of an anti-cancer agent, such as an oncolytic virus plasmid cocktail.

Abstract: The present invention provides a method and apparatus for supporting estimation of inter-satellite link acquisition times in a satellite constellation. The method includes computing or generating an indication of a statistical model based on observations for prior link acquisition times. The method further includes communicating an indication such as a statistical model for link acquisition times or related parameters through a communication network, or a combination thereof. The indication may be communicated using one or more transmission techniques or protocols, such as flooding, a link state protocol or gossip protocol. Based on the disseminated indication, future link acquisition times can be predicted by satellites in the satellite constellation. Embodiments of the invention use a statistical-based computation approach, such as regression modelling or random variable modelling, to estimate link acquisition times or associated estimation parameters.

Abstract: A method and apparatus for routing packets in a network, such as a satellite mesh network. For each one of multiple destination devices capable of further handling of the packet for routing to a destination (e.g. ground station) a respective cost or utility associated with forwarding the packet to that destination device is determined. For a given value k, an unsorted subset of k of the destination devices for which said costs are lowest or said utilities are highest is determined, without necessarily fully sorting the plurality of destination devices by cost or utility. The data packet is then forwarded to a selected one of this subset of destination devices. Cost may correspond to distance from destination device (e.g. satellite) to the further destination. Sorting networks and selector networks can be used, for example as implemented in hardware, to generate the unsorted subset.

Abstract: Disclosed herein are MDSC-targeted extracellular vesicles (EVs) loaded with therapeutic cargo, as well as compositions, systems, and methods for making same. Also disclosed herein is an MDSC-targeting ligand, such as a fusion protein containing an MDSC-targeting moiety. Also disclosed are EVs containing the disclosed fusion protein. In some embodiments, the EV is also loaded with a therapeutic cargo. Also disclosed is an EV-producing cell engineered to produce the disclosed EVs. Also disclosed is a method for making the disclosed EVs that involves culturing the disclosed EV-producing cells under conditions suitable to produce EVs.

Abstract: A method and apparatus for allocating server resources to services are provided. Multiple services compete for resources on one or more servers and bid for resources. Servers assign resources based on bids according to an auctioning rule mechanism. Services update bids according to a probabilistic dynamic that can approximate a continuous-time Markov chain, both for each service and for the collection of services. The method and apparatus can involve multiple separate but interacting agents, and can be implemented for example for self-organization of a datacentre. The behaviours of the agents can be configured so that the collective behaviour results in a proportional fair resource allocation.

Abstract: The present invention is provides a method and apparatus for routing a data packet in a network. For each nearby device capable of routing the packet toward a further destination, an associated cost or utility is determined. The device with lowest cost or highest utility is selected and the packet is forwarded toward same. The selecting may use a comparator tree. The cost or utility may be associated with forwarding the data packet from the candidate device toward the further destination. The cost or utility may be based on a distance from candidate device to the further destination, and may be determined using a Haversine function or approximation thereof, or by computing an inner product of a first vector and a second vector originating at a center of Earth, the first vector directed toward the candidate device, the second vector directed toward the further destination.

Abstract: A system and method for fair resource allocation includes a method. The method includes determining demand for a plurality of communications features of a network. The method further includes determining resource allocations for virtual computing instances hosted by a plurality of servers. The virtual computing instances serve the communications features. The method further includes adjusting the resource allocations for the virtual computing instances according to the demand for the communications features and a fairness algorithm.

Abstract: A wireless communication access node (WCAN) device includes radio frequency (RF) circuitry, RF interface (I/F) circuitry, network communication circuitry, memory, and/or processing circuitry. The WCAN device facilitates communications of a wireless communication device (e.g., User Equipment (UE)) in accordance with a policy profile record associated with the wireless communication device (e.g., policy profile record may be retrieved from a distributed cloud database that is distributedly implemented within the mobile backhaul communication system). The WCAN device collects communications statistics based on the communications of the wireless communication device and updates a communications statistics record associated with the wireless communication device within the distributed cloud database to include the communications statistics that are collected based on the communications of the wireless communication device.