Abstract: A new shape changing staple and instrument for the fixation of structures to include bone tissue and industrial materials. This new staple stores elastic mechanical energy to exert force on fixated structures to enhance their security and in bone affect its healing response. This staple once placed changes shape in response to geometric changes in the materials structure, including healing bone tissue. The staple is advanced over prior staples due to its: 1) method of operation, 2) high strength, 3) method of insertion, 4) compressive force temperature independence, 5) energy storing staple retention and delivery system, 6) compatibility with reusable or single use product configuration, 7) efficient and cost effective manufacturing methods, and 8) reduction in the steps required to place the device. In addition to the staple's industrial application an embodiment for use in the fixation of the musculoskeletal system is shown with staple, cartridge, and extrusion handle.

Abstract: A new shape changing staple and instrument for the fixation of structures to include bone tissue and industrial materials. This new staple stores elastic mechanical energy to exert force on fixated structures to enhance their security and in bone affect its healing response. This staple once placed changes shape in response to geometric changes in the materials structure, including healing bone tissue. The staple is advanced over prior staples due to its: 1) method of operation, 2) high strength, 3) method of insertion, 4) compressive force temperature independence, 5) energy storing staple retention and delivery system, 6) compatibility with reusable or single use product configuration, 7) efficient and cost effective manufacturing methods, and 8) reduction in the steps required to place the device. In addition to the staple's industrial application an embodiment for use in the fixation of the musculoskeletal system is shown with staple, cartridge, and extrusion handle.

Abstract: A method and apparatus for an osteotomy fixation or arthrodesis cage allows the adjustment of the relative position of two bone segments while supporting the joining of those bone segments into one structure through the implant and methods described herein. The implant's embodiments fixate to the adjacent bones while inter-positioning its body between the bone segments. This inter-positioning allows anatomical adjustments in the distance between and angle of the bone segments. The adjustment is further enhanced by the use of shape memory materials that when activated through the application of heat energy, transition from a second shape to a first shape while changing the distance between the bones or their relative angle. This method and apparatus can be used on any adjacent bone or bone segments including but not limited to the vertebrae of the spine or long bone such as the tibia or metatarsal.

Abstract: A shape-memory device manufactured from shape memory material includes multiple activation temperatures. The multiple activation temperatures arise from either the heat treatment of the device during manufacturing, or by combining different elements with different activation temperatures. To manufacture a shape-memory device with multiple activation temperatures, it is formed into a first shape. A first portion of the shape-memory device is heated to a first temperature, and a second portion of the shape-memory device is heated to a second temperature. The shape-memory device is then worked into a second shape. Accordingly, the first portion has a first transition temperature, and the second portion has a second transition temperature. In use, the shape-memory device is placed into a desired position. Energy is applied such that the first portion, second portion, or both portions are transformed.

Abstract: A staple constructed from shape memory material provides the ability to move from a first shape to any point up to and including a second shape. The staple includes a bridge having a first member and a second member, and allows the second member of the bridge to change elevation with respect to the first member, thereby creating compressive forces, offset forces, or distraction forces. Upon the application of energy, the second member moves upward or downward to deliver forces, dependent upon a desired effect. The staple further includes first and second legs for attaching to first and second bones. The offsetting forces may be utilized to offset the second bone relative to the first bone, or to align offset bones. The bridge may include a transition member or plurality of transition members in communication with the first and second members, whereby the transition member moves about the first member.

Abstract: Described is a new bone healing method and class of bone fixation implants that change shape once implanted so as to minimize non-healing and speed the bone healing process. The bone fixation method involves shape changing implants that continuously hold the bones in apposition so that a gap does not form. Gaps in time allow non-bony tissue to infiltrate and stop healing. Furthermore, the implants actively compress bone to increase bone mass and strength. Bone cell pressure due to compression and electrical current flow due to bone deformation act to stimulate healing. The new implant designs also provide a scaffolding to conduct bone through the implant and across the healing bone interface. The methods and designs are applicable to but not limited to use for bone screws, plates, staples, rods, cylinders and external fixation devices.

Abstract: A shape-memory device manufactured from shape memory material includes multiple activation temperatures. The multiple activation temperatures arise from either the heat treatment of the device during manufacturing, or by combining different elements with different activation temperatures. To manufacture a shape-memory device with multiple activation temperatures, it is formed into a first shape. A first portion of the shape-memory device is heated to a first temperature, and a second portion of the shape-memory device is heated to a second temperature. The shape-memory device is then worked into a second shape. Accordingly, the first portion has a first transition temperature, and the second portion has a second transition temperature. In use, the shape-memory device is placed into a desired position. Energy is applied such that the first portion, second portion, or both portions are transformed.

Abstract: A method and apparatus for an osteotomy fixation or arthrodesis cage allows the adjustment of the relative position of two bone segments while supporting the joining of those bone segments into one structure through the implant and methods described herein. The implant's embodiments fixate to the adjacent bones while inter-positioning its body between the bone segments. This inter-positioning allows anatomical adjustments in the distance between and angle of the bone segments. The adjustment is further enhanced by the use of shape memory materials that when activated through the application of heat energy, transition from a second shape to a first shape while changing the distance between the bones or their relative angle. This method and apparatus can be used on any adjacent bone or bone segments including but not limited to the vertebrae of the spine or long bone such as the tibia or metatarsal.

Abstract: A staple constructed from shape memory material provides the ability to move from a first shape to any point up to and including a second shape. The staple includes a bridge having a first member and a second member, and allows the second member of the bridge to change elevation with respect to the first member, thereby creating compressive forces, offset forces, or distraction forces. Upon the application of energy, the second member moves upward or downward to deliver forces, dependent upon a desired effect. The staple further includes first and second legs for attaching to first and second bones. The offsetting forces may be utilized to offset the second bone relative to the first bone, or to align offset bones. The bridge may include a transition member or plurality of transition members in communication with the first and second members, whereby the transition member moves about the first member.

Abstract: A bone staple extrusion instruments used for fixation of bone and soft tissue of the musculoskeletal system and the methods for their use and manufacture. The bone staple extrusion instruments are used for insertion of staples into bones, which staples change shape through their metallurgic properties and the release from the bone staple extrusion instruments. In some embodiments, the bone staples pull together and compress bone once released from the bone staple extrusion instruments. In other embodiments, the staples push outward to place the bones in tension once released from the bone staple extrusion instrument.

Abstract: A new shape changing staple and instrument for the fixation of structures to include bone tissue and industrial materials. This new staple stores elastic mechanical energy to exert force on fixated structures to enhance their security and in bone affect its healing response. This staple once placed changes shape in response to geometric changes in the materials structure, including healing bone tissue. The staple is advanced over prior staples due to its: 1) method of operation, 2) high strength, 3) method of insertion, 4) compressive force temperature independence, 5) energy storing staple retention and delivery system, 6) compatibility with reusable or single use product configuration, 7) efficient and cost effective manufacturing methods, and 8) reduction in the steps required to place the device. In addition to the staple's industrial application an embodiment for use in the fixation of the musculoskeletal system is shown with staple, cartridge, and extrusion handle.

Abstract: A new shape changing staple and instrument for the fixation of structures to include bone tissue and industrial materials. This new staple stores elastic mechanical energy to exert force on fixated structures to enhance their security and in bone affect its healing response. This staple once placed changes shape in response to geometric changes in the materials structure, including healing bone tissue. The staple is advanced over prior staples due to its: 1) method of operation, 2) high strength, 3) method of insertion, 4) compressive force temperature independence, 5) energy storing staple retention and delivery system, 6) compatibility with reusable or single use product configuration, 7) efficient and cost effective manufacturing methods, and 8) reduction in the steps required to place the device. In addition to the staple's industrial application an embodiment for use in the fixation of the musculoskeletal system is shown with staple, cartridge, and extrusion handle.

Abstract: A new shape changing staple and instrument for the fixation of structures to include bone tissue and industrial materials. This new staple stores elastic mechanical energy to exert force on fixated structures to enhance their security and in bone affect its healing response. This staple once placed changes shape in response to geometric changes in the materials structure, including healing bone tissue. The staple is advanced over prior staples due to its: 1) method of operation, 2) high strength, 3) method of insertion, 4) compressive force temperature independence, 5) energy storing staple retention and delivery system, 6) compatibility with reusable or single use product configuration, 7) efficient and cost effective manufacturing methods, and 8) reduction in the steps required to place the device. In addition to the staple's industrial application an embodiment for use in the fixation of the musculoskeletal system is shown with staple, cartridge, and extrusion handle.

Abstract: A new shape changing staple and instrument for the fixation of structures to include bone tissue and industrial materials. This new staple stores elastic mechanical energy to exert force on fixated structures to enhance their security and in bone affect its healing response. This staple once placed changes shape in response to geometric changes in the materials structure, including healing bone tissue. The staple is advanced over prior staples due to its: 1) method of operation, 2) high strength, 3) method of insertion, 4) compressive force temperature independence, 5) energy storing staple retention and delivery system, 6) compatibility with reusable or single use product configuration, 7) efficient and cost effective manufacturing methods, and 8) reduction in the steps required to place the device. In addition to the staple's industrial application an embodiment for use in the fixation of the musculoskeletal system is shown with staple, cartridge, and extrusion handle.

Abstract: A shape-memory device manufactured from shape memory material includes multiple activation temperatures. The multiple activation temperatures arise from either the heat treatment of the device during manufacturing, or by combining different elements with different activation temperatures. To manufacture a shape-memory device with multiple activation temperatures, it is formed into a first shape. A first portion of the shape-memory device is heated to a first temperature, and a second portion of the shape-memory device is heated to a second temperature. The shape-memory device is then worked into a second shape. Accordingly, the first portion has a first transition temperature, and the second portion has a second transition temperature. In use, the shape-memory device is placed into a desired position. Energy is applied such that the first portion, second portion, or both portions are transformed.

Abstract: Devices and methods for bone marrow aspiration, storage, and the combining of harvested marrow with biomaterials, therapeutic agents or medical devices are provided for the treatment or assessment on a variety of diseases or injuries. In a preferred embodiment, the invention includes aspiration of marrow into a cartridge to minimize bacterial contamination and clotting while facilitating handling, storage or the combining of harvested material with biomaterials, therapeutic agents or medical devices.

Abstract: A method and apparatus for an osteotomy fixation or arthrodesis cage allows the adjustment of the relative position of two bone segments while supporting the joining of those bone segments into one structure through the implant and methods described herein. The implant's embodiments fixate to the adjacent bones while inter-positioning its body between the bone segments. This inter-positioning allows anatomical adjustments in the distance between and angle of the bone segments. The adjustment is further enhanced by the use of shape memory materials that when activated through the application of heat energy, transition from a second shape to a first shape while changing the distance between the bones or their relative angle. This method and apparatus can be used on any adjacent bone or bone segments including but not limited to the vertebrae of the spine or long bone such as the tibia or metatarsal.

Abstract: A staple constructed from shape memory material provides the ability to move from a first shape to any point up to and including a second shape. The staple includes a bridge having a first member and a second member, and allows the second member of the bridge to change elevation with respect to the first member, thereby creating compressive forces, offset forces, or distraction forces. Upon the application of energy, the second member moves upward or downward to deliver forces, dependent upon a desired effect. The staple further includes first and second legs for attaching to first and second bones. The offsetting forces may be utilized to offset the second bone relative to the first bone, or to align offset bones. The bridge may include a transition member or plurality of transition members in communication with the first and second members, whereby the transition member moves about the first member.

Abstract: Controlling the transformation of the microstructure of shape memory material implants. A surgeon can use the inventive energy delivery device to control the rate of implant shape change, the extent of implant shape change, as well as the force exerted on the surrounding tissue. The invention allows for the fine control of force when fixating osteoporotic bone and rate of bone transport. This system models or measures the heating profile of the implant and provides the surgeon a method to control the extent of microstructure phase transformation so that the rate, force or extent of tissue movement can be controlled individually or together.