Patents by Inventor William Chour

William Chour has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • SINGLE CHAIN TRIMER MHC CLASS I NUCLEIC ACIDS AND PROTEINS AND METHODS OF USE
    Publication number: 20240239869
    Abstract: Peptide-major histocompatibility (MHC) Class I nucleic acids and proteins are provided. Methods of their use, for example in methods of identifying antigen-specific T cells and adoptive cell therapy, are also provided.
    Type: Application
    Filed: May 6, 2022
    Publication date: July 18, 2024
    Applicants: Institute for Systems Biology, California Institute of Technology
    Inventors: William Chour, James R. Heath, Jingyi Xie
  • SINGLE CHAIN TRIMER MHC CLASS II NUCLEIC ACIDS AND PROTEINS AND METHODS OF USE
    Publication number: 20230076204
    Abstract: Peptide-major histocompatibility (MHC) Class II nucleic acids and proteins are provided. Methods of their use, for example in methods of identifying antigen-specific T cells and adoptive cell therapy, are also provided.
    Type: Application
    Filed: February 18, 2021
    Publication date: March 9, 2023
    Applicants: Institute for Systems Biology, California Institute of Technology
    Inventors: James R. Heath, William Chour, Rongyu Zhang
  • Microfluidic devices and methods for purifying rare antigen-specific T cell populations
    Patent number: 11384327
    Abstract: Disclosed herein are methods and devices for antigen-specific T cell identification or neoantigen identification. Also disclosed herein are devices for separating and isolating antigen-specific T cells or other particles of a certain size from a population of particles of different sizes. Also describe herein are methods and devices for the separation and isolation of barcoded T cells from other nanoparticles containing barcodes for subsequent analysis and further processing of a viable T cell.
    Type: Grant
    Filed: November 1, 2017
    Date of Patent: July 12, 2022
    Assignees: California Institute of Technology, Gwangju Institute of Science and Technology (GIST)
    Inventors: Songming Peng, James R. Heath, William Chour, Alphonsus Hon-Chung Ng, Sung Yang, Jongchan Choi, Ji-Chul Hyun
  • MICROFLUIDIC DEVICES AND METHODS FOR PURIFYING RARE ANTIGEN-SPECIFIC T CELL POPULATIONS
    Publication number: 20200040293
    Abstract: Disclosed herein are methods and devices for antigen-specific T cell identification or neoantigen identification. Also disclosed herein are devices for separating and isolating antigen- specific T cells or other particles of a certain size from a population of particles of different sizes. Also describe herein are methods and devices for the separation and isolation of barcoded T cells from other nanoparticles containing barcodes for subsequent analysis and further processing of a viable T cell.
    Type: Application
    Filed: November 1, 2017
    Publication date: February 6, 2020
    Inventors: Songming Peng, James R. Heath, William Chour, Alphonsus H.c. Ng, Sung Yang, Jongchan Choi, Ji-Chul Hyun