Patents by Inventor William Clay Brown

William Clay Brown has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • SINGLE-CHAIN ANTIBODY AGAINST FLAVIVIRUS NS1 PROTEIN
    Publication number: 20240002479
    Abstract: The disclosure is directed to binding agents, e.g., a single chain variable fragment (scFv) that specifically binds to a flavivirus NS1 protein, as well as compositions comprising the binding agent and a method of using such compositions to induce an immune response against a flavivirus (e.g., a dengue virus). The disclosure also provides a conjugate comprising the binding agent, and a recombinant NS1 antigen.
    Type: Application
    Filed: November 23, 2021
    Publication date: January 4, 2024
    Inventors: Janet L. Smith, David L. Akey, William Clay Brown, Eva Harris, Scott B. Biering, P. Robert Beatty
  • Protein purification tags and uses thereof
    Patent number: 8357511
    Abstract: The present invention relates to fusion proteins. In particular, the present invention relates to protein tags for use in protein solubilization and purification.
    Type: Grant
    Filed: July 31, 2009
    Date of Patent: January 22, 2013
    Assignee: The Regents of the University of Michigan
    Inventors: William Clay Brown, James E. Delproposto, Janet Smith
  • PROTEIN PURIFICATION TAGS AND USES THEREOF
    Publication number: 20110165624
    Abstract: The present invention relates to fusion proteins. In particular, the present invention relates to protein tags for use in protein solubilization and purification.
    Type: Application
    Filed: July 31, 2009
    Publication date: July 7, 2011
    Applicant: THE REGENTS OF THEUNIVERSITY OF MICHIGAN
    Inventors: William Clay Brown, James E. Delproposto, Janet Smith