Abstract: The present disclosure relates to a lighting component which may comprise a light emitting diode (LED) or laser diode (LD) for generating at least one of blue light or ultraviolet light. A fluoride phosphor matrix may be included, which may be consolidated into a phosphor ceramic structure including at least one of a transparent fluoride ceramic structure or a translucent fluoride ceramic structure, and positioned adjacent to the LED or LD. The phosphor ceramic structure generates at least one of red or orange light when irradiated by the light emitted from the LED or LD. The phosphor ceramic structure exhibits reduced thermal quenching relative to a fluoride particulate structure irradiated by the LED or LD.

Abstract: According to some embodiments, a method of promoting hair growth or hair stimulation in a subject comprises applying vacuum or suction using a handpiece assembly along a targeted portion of the subject's skin surface where hair growth or hair stimulation is desired and providing at least one treatment material to said targeted portion of the subject's skin surface, wherein the application of vacuum or suction helps promote hair growth or stimulate hair.

Abstract: The present invention is an applicator tip for a hand piece assembly used in dermal abrasion procedures, the applicator tip having a cap shape with a plurality of apertures that form ports communicating with a fluid supply line in the hand piece assembly and a vacuum source to remove the abrading fluid. The fluid is introduced onto the outer abrading surface of the applicator tip through a first central aperture and spreads out along the outer abrading surface when the applicator tip is placed against the patient's skin. Recesses in the outer abrading surface establish pathways for the abrading fluid to move along as the applicator tip is moved over the patient's skin. The fluid emitting from the central port is moved into one of four quadrants defined by recesses in the outer abrading surface, each quadrant serving as a fluid chamber that receives fluid from the central fluid supply port. Each sector shaped chamber includes within its border a C-shaped barrier with its opening facing a dividing sector wall.

Abstract: Described herein are veterinary progastrin binding molecules (VPBM) against veterinary progastrin-like molecules (VPM) and the methods of making and using the VPBM thereof. Also described, are compositions comprising binding domains of VPBM against VPM and methods of making an using thereof.

Abstract: An apparatus for treating skin has a console with a user input device and a handpiece assembly. The handpiece assembly is configured to treat skin. A fluid line provides fluid communication between the console and the handpiece assembly. A manifold system is coupled to the console and controlled by the user input device. The manifold system is configured to hold releasably a plurality of fluid sources and deliver fluid from at least one of the plurality of fluid sources to the handpiece assembly.

Abstract: An apparatus for treating skin has a console with a user input device and a handpiece assembly. The handpiece assembly is configured to treat skin. A fluid line provides fluid communication between the console and the handpiece assembly. A manifold system is coupled to the console and controlled by the user input device. The manifold system is configured to hold releasably a plurality of fluid sources and deliver fluid from at least one of the plurality of fluid sources to the handpiece assembly.

Abstract: The present disclosure relates to a lighting component which may comprise a light emitting diode (LED) or laser diode (LD) for generating at least one of blue light or ultraviolet light. A fluoride phosphor matrix may be included, which may be consolidated into a phosphor ceramic structure including at least one of a transparent fluoride ceramic structure or a translucent fluoride ceramic structure, and positioned adjacent to the LED or LD. The phosphor ceramic structure generates at least one of red or orange light when irradiated by the light emitted from the LED or LD. The phosphor ceramic structure exhibits reduced thermal quenching relative to a fluoride particulate structure irradiated by the LED or LD.

Abstract: An apparatus for treating skin has a console with a user input device and a handpiece assembly. The handpiece assembly is configured to treat skin. A fluid line provides fluid communication between the console and the handpiece assembly. A manifold system is coupled to the console and controlled by the user input device. The manifold system is configured to hold releasably a plurality of fluid sources and deliver fluid from at least one of the plurality of fluid sources to the handpiece assembly.

Abstract: An apparatus for treating skin has a console with a user input device and a handpiece assembly. The handpiece assembly is configured to treat skin. A fluid line provides fluid communication between the console and the handpiece assembly. A manifold system is coupled to the console and controlled by the user input device. The manifold system is configured to hold releasably a plurality of fluid sources and deliver fluid from at least one of the plurality of fluid sources to the handpiece assembly.

Abstract: An apparatus for treating skin has a console with a user input device and a handpiece assembly. The handpiece assembly is configured to treat skin. A fluid line provides fluid communication between the console and the handpiece assembly. A manifold system is coupled to the console and controlled by the user input device. The manifold system is configured to hold releasably a plurality of fluid sources and deliver fluid from at least one of the plurality of fluid sources to the handpiece assembly.

Abstract: An apparatus for treating skin has a console with a user input device and a handpiece assembly. The handpiece assembly is configured to treat skin. A fluid line provides fluid communication between the console and the handpiece assembly. A manifold system is coupled to the console and controlled by the user input device. The manifold system is configured to hold releasably a plurality of fluid sources and deliver fluid from at least one of the plurality of fluid sources to the handpiece assembly.

Abstract: An apparatus for treating skin has a console with a user input device and a handpiece assembly. The handpiece assembly is configured to treat skin. A fluid line provides fluid communication between the console and the handpiece assembly. A manifold system is coupled to the console and controlled by the user input device. The manifold system is configured to hold releasably a plurality of fluid sources and deliver fluid from at least one of the plurality of fluid sources to the handpiece assembly.

Abstract: The present invention is an applicator tip for a hand piece assembly used in dermal abrasion procedures, the applicator tip having a cap shape with a plurality of apertures that form ports communicating with a fluid supply line in the hand piece assembly and a vacuum source to remove the abrading fluid. The fluid is introduced onto the outer abrading surface of the applicator tip through a first central aperture and spreads out along the outer abrading surface when the applicator tip is placed against the patient's skin. Recesses in the outer abrading surface establish pathways for the abrading fluid to move along as the applicator tip is moved over the patient's skin. The fluid emitting from the central port is moved into one of four quadrants defined by recesses in the outer abrading surface, each quadrant serving as a fluid chamber that receives fluid from the central fluid supply port. Each sector shaped chamber includes within its border a C-shaped barrier with its opening facing a dividing sector wall.

Abstract: An apparatus for treating skin has a console with a user input device and a handpiece assembly. The handpiece assembly is configured to treat skin. A fluid line provides fluid communication between the console and the handpiece assembly. A manifold system is coupled to the console and controlled by the user input device. The manifold system is configured to hold releasably a plurality of fluid sources and deliver fluid from at least one of the plurality of fluid sources to the handpiece assembly.

Abstract: According to some embodiments, a method of promoting hair growth or hair stimulation in a subject comprises applying vacuum or suction using a handpiece assembly along a targeted portion of the subject's skin surface where hair growth or hair stimulation is desired and providing at least one treatment material to said targeted portion of the subject's skin surface, wherein the application of vacuum or suction helps promote hair growth or stimulate hair.

Abstract: The present invention is an applicator tip for a hand piece assembly used in dermal abrasion procedures, the applicator tip having a cap shape with a plurality of apertures that form ports communicating with a fluid supply line in the hand piece assembly and a vacuum source to remove the abrading fluid. The fluid is introduced onto the outer abrading surface of the applicator tip through a first central aperture and spreads out along the outer abrading surface when the applicator tip is placed against the patient's skin. Recesses in the outer abrading surface establish pathways for the abrading fluid to move along as the applicator tip is moved over the patient's skin. The fluid emitting from the central port is moved into one of four quadrants defined by recesses in the outer abrading surface, each quadrant serving as a fluid chamber that receives fluid from the central fluid supply port. Each sector shaped chamber includes within its border a C-shaped barrier with its opening facing a dividing sector wall.

Abstract: According to some embodiments, a method of promoting hair growth or hair stimulation in a subject comprises applying vacuum or suction using a handpiece assembly along a targeted portion of the subject's skin surface where hair growth or hair stimulation is desired and providing at least one treatment material to said targeted portion of the subject's skin surface, wherein the application of vacuum or suction helps promote hair growth or stimulate hair.

Abstract: The present invention is an applicator tip for a hand piece assembly used in dermal abrasion procedures, the applicator tip having a cap shape with a plurality of apertures that form ports communicating with a fluid supply line in the hand piece assembly and a vacuum source to remove the abrading fluid. The fluid is introduced onto the outer abrading surface of the applicator tip through a first central aperture and spreads out along the outer abrading surface when the applicator tip is placed against the patient's skin. Recesses in the outer abrading surface establish pathways for the abrading fluid to move along as the applicator tip is moved over the patient's skin. The fluid emitting from the central port is moved into one of four quadrants defined by recesses in the outer abrading surface, each quadrant serving as a fluid chamber that receives fluid from the central fluid supply port. Each sector shaped chamber includes within its border a C-shaped barrier with its opening facing a dividing sector wall.

Abstract: An apparatus for treating skin has a console with a user input device and a handpiece assembly. The handpiece assembly is configured to treat skin. A fluid line provides fluid communication between the console and the handpiece assembly. A manifold system is coupled to the console and controlled by the user input device. The manifold system is configured to hold releasably a plurality of fluid sources and deliver fluid from at least one of the plurality of fluid sources to the handpiece assembly.

Abstract: An apparatus for treating skin has a console with a user input device and a handpiece assembly. The handpiece assembly is configured to treat skin. A fluid line provides fluid communication between the console and the handpiece assembly. A manifold system is coupled to the console and controlled by the user input device. The manifold system is configured to hold releasably a plurality of fluid sources and deliver fluid from at least one of the plurality of fluid sources to the handpiece assembly.