Abstract: An automated carrier system is disclosed for moving objects to be processed. The automated carrier system includes a discontinuous plurality of track sections on which an automated carrier may be directed to move, and the automated carrier includes a base structure on which an object may be supported, and at least two wheels assemblies being pivotally supported on the base structure for pivoting movement from a first position to a second position to effect a change in direction of movement of the carrier.

Abstract: An electrochemical cell and battery system including cells, each cell including a catholyte, an anolyte, and a separator disposed between the catholyte and anolyte and that is permeable to the at least one ionic species (for example, a metal cation or the hydroxide ion). The catholyte solution includes a ferricyanide, permanganate, manganate, sulfur, and/or polysulfide compound, and the anolyte includes a sulfide and/or polysulfide compound. These electrochemical couples may be embodied in various physical architectures, including static (non-flowing) architectures or in flow battery (flowing) architectures.

Abstract: Provided herein are compositions comprising novel MHC class II T cell epitopes and method using thereof. In some embodiments, a composition described herein comprises an immunogenic polypeptide comprising an MHC class II T cell epitope and a target antigen. In some embodiments, the target antigen is a viral, bacterial, parasite or tumor specific antigen. In some embodiments, the target antigen comprises a virus, bacteria, parasite or tumor specific polypeptide. In some embodiments, the composition comprises a fusion polypeptide comprising the immunogenic polypeptide and the target polypeptide. Also provided are polynucleotides encoding the fusion polypeptide, and methods of administering a composition comprising the polynucleotide to a subject to elicit an immune response. In some embodiments, the polynucleotide is an RNA comprising modified ribonucleotides.

Abstract: The present invention is directed to a method of making at least a portion of a garment that includes at least one three-dimensional contour. The disclosed method includes providing a fiber and solvent mixture that includes fibers and a solvent capable to causing a plurality of covalent bonds to be created between the fibers. In many embodiments, the plurality of covalent bonds form when a catalyst, such as heat, is provided to the fiber and solvent mixture. The process can be performed using, for example, either a 3D printer or mold form. The fibers used can be natural, synthetic, or a blend of natural and/or synthetic fibers. The solvent preferably includes ionic salts in water.

Abstract: Nucleic acids encoding C1 inhibitor are described. Also described are expression cassettes, vectors, cells, and cell lines containing the nucleic acids, as well as methods of using the nucleic acids to treat complement-mediated disorders, such as hereditary angioedema.

Abstract: A storage, retrieval and processing system for processing objects is disclosed. The storage, retrieval and processing system includes a plurality of storage bins providing storage of a plurality of objects, where the plurality of storage bins is in communication with a retrieval conveyance system, a programmable motion device in communication with the retrieval conveyance system for receiving the storage bins from the plurality of bins, where the programmable motion device includes an end effector for grasping and moving a selected object out of a selected storage bin, and a movable carriage for receiving the selected object from the end effector of the programmable motion device, and for carrying the selected object to one of a plurality of destination bins.

Abstract: The present disclosure relates to a lighting component which may comprise a light emitting diode (LED) or laser diode (LD) for generating at least one of blue light or ultraviolet light. A fluoride phosphor matrix may be included, which may be consolidated into a phosphor ceramic structure including at least one of a transparent fluoride ceramic structure or a translucent fluoride ceramic structure, and positioned adjacent to the LED or LD. The phosphor ceramic structure generates at least one of red or orange light when irradiated by the light emitted from the LED or LD. The phosphor ceramic structure exhibits reduced thermal quenching relative to a fluoride particulate structure irradiated by the LED or LD.

Abstract: An apparatus for treating skin has a console with a user input device and a handpiece assembly. The handpiece assembly is configured to treat skin. A fluid line provides fluid communication between the console and the handpiece assembly. A manifold system is coupled to the console and controlled by the user input device. The manifold system is configured to hold releasably a plurality of fluid sources and deliver fluid from at least one of the plurality of fluid sources to the handpiece assembly.

Abstract: An apparatus for treating skin has a console with a user input device and a handpiece assembly. The handpiece assembly is configured to treat skin. A fluid line provides fluid communication between the console and the handpiece assembly. A manifold system is coupled to the console and controlled by the user input device. The manifold system is configured to hold releasably a plurality of fluid sources and deliver fluid from at least one of the plurality of fluid sources to the handpiece assembly.

Abstract: An apparatus for treating skin has a console with a user input device and a handpiece assembly. The handpiece assembly is configured to treat skin. A fluid line provides fluid communication between the console and the handpiece assembly. A manifold system is coupled to the console and controlled by the user input device. The manifold system is configured to hold releasably a plurality of fluid sources and deliver fluid from at least one of the plurality of fluid sources to the handpiece assembly.

Abstract: An apparatus for treating skin has a console with a user input device and a handpiece assembly. The handpiece assembly is configured to treat skin. A fluid line provides fluid communication between the console and the handpiece assembly. A manifold system is coupled to the console and controlled by the user input device. The manifold system is configured to hold releasably a plurality of fluid sources and deliver fluid from at least one of the plurality of fluid sources to the handpiece assembly.

Abstract: An apparatus for treating skin has a console with a user input device and a handpiece assembly. The handpiece assembly is configured to treat skin. A fluid line provides fluid communication between the console and the handpiece assembly. A manifold system is coupled to the console and controlled by the user input device. The manifold system is configured to hold releasably a plurality of fluid sources and deliver fluid from at least one of the plurality of fluid sources to the handpiece assembly.

Abstract: The present invention is an applicator tip for a hand piece assembly used in dermal abrasion procedures, the applicator tip having a cap shape with a plurality of apertures that form ports communicating with a fluid supply line in the hand piece assembly and a vacuum source to remove the abrading fluid. The fluid is introduced onto the outer abrading surface of the applicator tip through a first central aperture and spreads out along the outer abrading surface when the applicator tip is placed against the patient's skin. Recesses in the outer abrading surface establish pathways for the abrading fluid to move along as the applicator tip is moved over the patient's skin. The fluid emitting from the central port is moved into one of four quadrants defined by recesses in the outer abrading surface, each quadrant serving as a fluid chamber that receives fluid from the central fluid supply port. Each sector shaped chamber includes within its border a C-shaped barrier with its opening facing a dividing sector wall.

Abstract: An apparatus for treating skin has a console with a user input device and a handpiece assembly. The handpiece assembly is configured to treat skin. A fluid line provides fluid communication between the console and the handpiece assembly. A manifold system is coupled to the console and controlled by the user input device. The manifold system is configured to hold releasably a plurality of fluid sources and deliver fluid from at least one of the plurality of fluid sources to the handpiece assembly.

Abstract: According to some embodiments, a method of promoting hair growth or hair stimulation in a subject comprises applying vacuum or suction using a handpiece assembly along a targeted portion of the subject's skin surface where hair growth or hair stimulation is desired and providing at least one treatment material to said targeted portion of the subject's skin surface, wherein the application of vacuum or suction helps promote hair growth or stimulate hair.

Abstract: The present invention is an applicator tip for a hand piece assembly used in dermal abrasion procedures, the applicator tip having a cap shape with a plurality of apertures that form ports communicating with a fluid supply line in the hand piece assembly and a vacuum source to remove the abrading fluid. The fluid is introduced onto the outer abrading surface of the applicator tip through a first central aperture and spreads out along the outer abrading surface when the applicator tip is placed against the patient's skin. Recesses in the outer abrading surface establish pathways for the abrading fluid to move along as the applicator tip is moved over the patient's skin. The fluid emitting from the central port is moved into one of four quadrants defined by recesses in the outer abrading surface, each quadrant serving as a fluid chamber that receives fluid from the central fluid supply port. Each sector shaped chamber includes within its border a C-shaped barrier with its opening facing a dividing sector wall.

Abstract: According to some embodiments, a method of promoting hair growth or hair stimulation in a subject comprises applying vacuum or suction using a handpiece assembly along a targeted portion of the subject's skin surface where hair growth or hair stimulation is desired and providing at least one treatment material to said targeted portion of the subject's skin surface, wherein the application of vacuum or suction helps promote hair growth or stimulate hair.

Abstract: The present invention is an applicator tip for a hand piece assembly used in dermal abrasion procedures, the applicator tip having a cap shape with a plurality of apertures that form ports communicating with a fluid supply line in the hand piece assembly and a vacuum source to remove the abrading fluid. The fluid is introduced onto the outer abrading surface of the applicator tip through a first central aperture and spreads out along the outer abrading surface when the applicator tip is placed against the patient's skin. Recesses in the outer abrading surface establish pathways for the abrading fluid to move along as the applicator tip is moved over the patient's skin. The fluid emitting from the central port is moved into one of four quadrants defined by recesses in the outer abrading surface, each quadrant serving as a fluid chamber that receives fluid from the central fluid supply port. Each sector shaped chamber includes within its border a C-shaped barrier with its opening facing a dividing sector wall.

Abstract: An apparatus for treating skin has a console with a user input device and a handpiece assembly. The handpiece assembly is configured to treat skin. A fluid line provides fluid communication between the console and the handpiece assembly. A manifold system is coupled to the console and controlled by the user input device. The manifold system is configured to hold releasably a plurality of fluid sources and deliver fluid from at least one of the plurality of fluid sources to the handpiece assembly.

Abstract: An apparatus for treating skin has a console with a user input device and a handpiece assembly. The handpiece assembly is configured to treat skin. A fluid line provides fluid communication between the console and the handpiece assembly. A manifold system is coupled to the console and controlled by the user input device. The manifold system is configured to hold releasably a plurality of fluid sources and deliver fluid from at least one of the plurality of fluid sources to the handpiece assembly.