Patents by Inventor William D. Bloomer

William D. Bloomer has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Method of treating latent tuberculosis
    Patent number: 7618986
    Abstract: 2-Nitroimidazolyl-alkylaminoquinolines, and compositions containing the same, useful in the treatment of tuberculosis are disclosed. Methods of treating tuberculosis using the 2-nitroimidazolyl-alkylaminoquinolines, and compositions containing the same, also are disclosed.
    Type: Grant
    Filed: August 23, 2007
    Date of Patent: November 17, 2009
    Assignee: Evanston Northwestern Healthcare
    Inventors: Maria V. Papadopoulou, William D. Bloomer
  • DNA-affinic hypoxia selective cytotoxins
    Patent number: 5602142
    Abstract: Hypoxia selective cytotoxins having the structural formula ##STR1## wherein D, E, F and G, independently, are carbon or nitrogen, with the proviso that three or more of D, E, F and G are carbon; R.sub.1 and R.sub.2, independently, are selected from the group consisting of methyl, halo, hydro, trifluoromethyl, methoxy, cyano, and methylsulfo; R.sub.3 and R.sub.4, independently, are selected from the group consisting of methyl, ethyl, phenyl, naphthyl, tertiary butyl, halo, halomethylene, hydro, trifluoromethyl, cyano and methylsulfo, or R.sub.3 and R.sub.4 taken together are a substituted or unsubstituted five or six-membered nonaromatic ring system; n is an integer 1 through 5; X is carbon or nitrogen; and Z is a physiologically acceptable anion, are disclosed. The compounds are useful as radiosensitizers or chemosensitizers, especially in the treatment of cancer patients.
    Type: Grant
    Filed: December 21, 1994
    Date of Patent: February 11, 1997
    Assignee: Evanston Hospital Corporation
    Inventors: Maria V. Papadopoulou-Rosenzweig, William D. Bloomer
  • Acridine-intercalator based hypoxia selective cytotoxins
    Patent number: 5294715
    Abstract: Hypoxia selective cytotoxins of the general formula ##STR1## wherein n is from 1 to 5, and NO.sub.2 is in at least one of the 2, 4 or 5-positions of the imidazole. Such compounds have utility as radiosensitizers and chemosensitizers.
    Type: Grant
    Filed: February 1, 1991
    Date of Patent: March 15, 1994
    Assignee: University of Pittsburgh
    Inventors: Maria Papadopoulou-Rosenzweig, William D. Bloomer, William D. Bloomer
  • Astatinated organic compounds
    Patent number: 4826672
    Abstract: Methods and kits for incorporating a radioactive astatine isotope (particularly .sup.211 At) into an organic compound by electrophilic astatodestannylation of organostannanes.
    Type: Grant
    Filed: June 7, 1985
    Date of Patent: May 2, 1989
    Assignee: President and Fellows of Harvard College
    Inventors: Richard A. Milius, Richard M. Lambrecht, William D. Bloomer