Abstract: A lipid vesicle comprising a functionalized lipid comprising a tether moiety having binding affinity for a ligand portion of an active agent and the active agent are provided. Methods of decorating endothelial cells, tissues, and organs with active agents utilizing the disclosed lipid vesicles are also provided.

Abstract: A lipid vesicle comprising a phospholipid which is a stable vesicle former and at least one unstable vesicle forming member, wherein the unstable vesicle forming member is selected from the group consisting of a polar lipid which is not a stable vesicle former, a PEG, a raft former and a fusion protein is provided. The vesicle can further comprise a biomolecule, such as for example ATP. Methods of using the vesicle for delivery of biomolecules are also provided.

Abstract: A temperature controlled tissue dissection and observation stage comprises a central working area and a first temperature controlled station positioned within the central working area. The first temperature controlled station comprises a first temperature controlling element configured to adjust the temperature of the first temperature controlled station. The stage further comprises a user input device in communication with the first temperature controlling element. In one embodiment, the stage comprises four temperature controlled stations. Three of these stations are designed to house petri dishes filled with solutions required for tissue restoration and reconstruction surgeries, and the fourth station is configured to function as a flat cutting surface for the user. In one embodiment, thermostatic control over the system is achieved through the integration of thermoelectric coolers, a microcontroller, and feedback temperature sensors.

Abstract: Infusion pumps that do not require electricity for operation are disclosed for various applications, including but not limited to pharmaceutical delivery of medications. A substance, which can be liquid, is stored in a reservoir and driven pneumatically by pressure generated by thermal transpiration, which requires a temperature difference existing between two ends of a narrow channel. In the case of pharmaceutical delivery, the medication is delivered to the treatment site via an applicator. Power sources other than electricity include, but are not limited to, the temperature of a person's body heat exceeding the ambient temperature of surrounding air.

Abstract: A lipid vesicle comprising a phospholipid which is a stable vesicle former and at least one unstable vesicle forming member, wherein the unstable vesicle forming member is selected from the group consisting of a polar lipid which is not a stable vesicle former, a PEG, a raft former and a fusion protein is provided. The vesicle can further comprise a biomolecule, such as for example ATP. Methods of using the vesicle for delivery of biomolecules are also provided.

Abstract: A lipid vesicle comprising a functionalized lipid comprising a tether moiety having binding affinity for a ligand portion of an active agent and the active agent are provided. Methods of decorating endothelial cells, tissues, and organs with active agents utilizing the disclosed lipid vesicles are also provided.

Abstract: A vesicle comprises ATP and a phospholipid which is a stable vesicle former. The vesicle has a fusion rate of at least 20 vesicle fusions/second.

Abstract: A wound-healing composition comprises a wound-treating component and vesicles. The vesicles comprise a phospholipid which is a stable vesicle former and ATP.

Abstract: A wound-healing composition comprises a wound-treating component and vesicles. The vesicles comprise a phospholipid which is a stable vesicle former and ATP.

Abstract: A vesicle comprises ATP and a phospholipid which is a stable vesicle former. The vesicle has a fusion rate of at least 20 vesicle fusions/second.