Patents by Inventor William D. Gregory

William D. Gregory has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Patent number: 11617518
    Abstract: A method for characterizing tissues within a subject as cancerous or non-cancerous includes determining the electrical properties of the subject. The electrical properties of the subject are fit to a model and a specific range of a set of characteristic frequencies of each tissue is then calculated. Each tissue is finally characterized as cancerous or non-cancerous if the specific range of the set of characteristic frequencies inside or outside, respectively, a pre-determined spread of characteristic frequencies.
    Type: Grant
    Filed: March 15, 2013
    Date of Patent: April 4, 2023
    Assignee: WISYS TECHNOLOGY FOUNDATION, INC.
    Inventors: William D Gregory, Christopher W Gregory, John R Shell
  • Patent number: 9066671
    Abstract: A system and method for detecting cancerous tissue in a subject is provided. More specifically, the present invention provides a system and method for non-invasively identifying cancerous regions in breast tissue. The system includes a sensor system, a drive system, and a processor. The sensor system includes a sensor plate and, similarly, the drive system includes a drive plate. A time-varying voltage is applied to the drive plate and induced currents are subsequently measured by the sensor plate. Signals indicative of an induced current are then acquired and analyzed by the processor to determine the spatial location of anomalous regions. Subsequently, the anomalous regions are characterized as either cancerous or non-cancerous.
    Type: Grant
    Filed: April 17, 2009
    Date of Patent: June 30, 2015
    Assignee: WISYS TECHNOLOGY FOUNDATION
    Inventors: William D. Gregory, Christopher Gregory
  • Patent number: 9042975
    Abstract: A device and method for accurately characterizing tissue impedance employs multiple electrodes at a plurality of separation distances to cancel the effects of front end loading leakage currents and electrode polarization to improve the accuracy of sensitive impedance measurements used to identify cancerous tissues. These measurements may be automated over a range of frequencies.
    Type: Grant
    Filed: May 2, 2011
    Date of Patent: May 26, 2015
    Assignee: WISYS TECHNOLOGY FOUNDATION
    Inventor: William D. Gregory
  • Publication number: 20130211280
    Abstract: A method for characterizing tissues within a subject as cancerous or non-cancerous includes determining the electrical properties of the subject. The electrical properties of the subject are fit to a model and a specific range of a set of characteristic frequencies of each tissue is then calculated. Each tissue is finally characterized as cancerous or non-cancerous if the specific range of the set of characteristic frequencies inside or outside, respectively, a pre-determined spread of characteristic frequencies.
    Type: Application
    Filed: March 15, 2013
    Publication date: August 15, 2013
    Inventors: William D. Gregory, Christopher W W. Gregory, John R. Shell
  • Patent number: 8467865
    Abstract: A method for characterizing tissues within a subject as cancerous or non-cancerous includes determining the electrical properties of the subject. The electrical properties of the subject are fit to a model and a characteristic frequency of each tissue is then calculated. Each tissue is finally characterized as cancerous or non-cancerous if its characteristic frequency lies above a threshold value.
    Type: Grant
    Filed: March 5, 2008
    Date of Patent: June 18, 2013
    Assignee: WiSys Technology Foundation
    Inventors: William D. Gregory, Christopher W. Gregory
  • Patent number: 8052930
    Abstract: A device for characterizing ex vivo tissue employs a set of independent electrodes that may be used to scan the tissue by moving a voltage gradient across the tissue surface acquiring impedance spectrographs that may be mapped to an image.
    Type: Grant
    Filed: April 2, 2009
    Date of Patent: November 8, 2011
    Assignee: WiSys Technology Foundation
    Inventor: William D. Gregory
  • Publication number: 20110270066
    Abstract: A device and method for accurately characterizing tissue impedance employs multiple electrodes at a plurality of separation distances to cancel the effects of front end loading leakage currents and electrode polarization to improve the accuracy of sensitive impedance measurements used to identify cancerous tissues. These measurements may be automated over a range of frequencies.
    Type: Application
    Filed: May 2, 2011
    Publication date: November 3, 2011
    Inventor: William D. Gregory
  • Patent number: 7627362
    Abstract: An electrical parameter imaging apparatus and method includes the acquisition of a charge distribution pattern on an array of electrodes that surround an object being imaged. In addition the exterior boundary, or contours of the object is measured by an array of light beams and associated light sensors. The contour measurement is employed to provide a first estimate of the object geometry needed to compute an electrical parameter image from the acquired charge distribution pattern.
    Type: Grant
    Filed: November 4, 2003
    Date of Patent: December 1, 2009
    Assignee: WiSys Technology Foundation
    Inventors: Christopher William Gregory, William D. Gregory
  • Publication number: 20090264791
    Abstract: A system and method for detecting cancerous tissue in a subject is provided. More specifically, the present invention provides a system and method for non-invasively identifying cancerous regions in breast tissue. The system includes a sensor system, a drive system, and a processor. The sensor system includes a sensor plate and, similarly, the drive system includes a drive plate. A time-varying voltage is applied to the drive plate and induced currents are subsequently measured by the sensor plate. Signals indicative of an induced current are then acquired and analyzed by the processor to determine the spatial location of anomalous regions. Subsequently, the anomalous regions are characterized as either cancerous or non-cancerous.
    Type: Application
    Filed: April 17, 2009
    Publication date: October 22, 2009
    Inventors: William D. Gregory, Christopher Gregory
  • Publication number: 20090253193
    Abstract: A device for characterizing ex vivo tissue employs a set of independent electrodes that may be used to scan the tissue by moving a voltage gradient across the tissue surface acquiring impedance spectrographs that may be mapped to an image.
    Type: Application
    Filed: April 2, 2009
    Publication date: October 8, 2009
    Inventor: William D. Gregory
  • Publication number: 20080221475
    Abstract: A method for characterizing tissues within a subject as cancerous or non-cancerous includes determining the electrical properties of the subject. The electrical properties of the subject are fit to a model and a characteristic frequency of each tissue is then calculated. Each tissue is finally characterized as cancerous or non-cancerous if its characteristic frequency lies above a threshold value.
    Type: Application
    Filed: March 5, 2008
    Publication date: September 11, 2008
    Inventors: William D. Gregory, Christopher W. Gregory
  • Publication number: 20040167421
    Abstract: An electrical parameter imaging apparatus and method includes the acquisition of a charge distribution pattern on an array of electrodes that surround an object being imaged. In addition the exterior boundary, or contours of the object is measured by an array of light beams and associated light sensors. The contour measurement is employed to provide a first estimate of the object geometry needed to compute an electrical parameter image from the acquired charge distribution pattern.
    Type: Application
    Filed: November 4, 2003
    Publication date: August 26, 2004
    Inventors: Christopher William Gregory, William D. Gregory
  • Patent number: 6763263
    Abstract: An electrical property imaging system includes an array of sensors placed around an object to measure the surface charges thereon as a sinusoidal voltage is applied thereacross. The resulting distribution of charges inside the object are calculated using a stored charge correlation matrix. Electrical property images are produced from the internal charge distribution image.
    Type: Grant
    Filed: July 26, 2001
    Date of Patent: July 13, 2004
    Assignee: WiSys Technology Foundation
    Inventors: Christopher William Gregory, William D. Gregory
  • Patent number: 6522910
    Abstract: Enhanced information on the electrical properties of the subregions of a sample is generated by an enhanced tomography (EPET) apparatus connected to a tomographic device, wherein the EPET apparatus holds a voltage constant and measures the electrical current of the sample inserted within the EPET apparatus. A matching medium is applied to the sample such that when the sample is placed within an electromagnetic field generated by the EPET apparatus, the matching medium contacts the segmented sensor plates of the EPET apparatus and allows the detection of the net total charges Q on the surface of the sample. The EPET apparatus uses these net total charges Q in the calculation of the additional information on the electrical properties of the sample by using the scale factor method or the iterative correction method.
    Type: Grant
    Filed: March 8, 2000
    Date of Patent: February 18, 2003
    Assignee: WiSys Technology Foundation
    Inventor: William D. Gregory
  • Publication number: 20020038096
    Abstract: An electrical property imaging system includes an array of sensors placed around an object to measure the surface charges thereon as a sinusoidal voltage is applied thereacross. The resulting distribution of charges inside the object are calculated using a stored charge correlation matrix. Electrical property images are produced from the internal charge distribution image.
    Type: Application
    Filed: July 26, 2001
    Publication date: March 28, 2002
    Inventors: Christopher William Gregory, William D. Gregory
  • Patent number: 4881025
    Abstract: Packaged materials are tested in a capacitive sensor which has plates whose spacing can be accurately adjusted, and whose plates are segmented so that selected segments can be employed. An a.c. voltage is applied across the capacitive plates at accurately known amplitude, phase, and frequency for a number of frequencies. A ratio bridge is tied to each number of frequencies. A ratio bridge is tied to each of the segments and provides outputs that reflect the a.c. voltage and current, both capacitive and ohmic. A zero-crossing detection method or time domain method can be employed to provide precise amplitude and phase, or a quadrature or phase-sensitive detection method can provide amplitude and phase, or a quadrature or phase-sensitive detection method can provide amplitude and phase of the a.c. current through each segment.
    Type: Grant
    Filed: September 26, 1988
    Date of Patent: November 14, 1989
    Assignee: Trustees of the Diotec Trust
    Inventor: William D. Gregory
  • Patent number: 4800256
    Abstract: An improved holographic scanner includes circuitry for adjusting the frequency with which an analog photodetector signal is sampled in accordance with the focal length of the scanning beam produced by the active holographic facet. Two embodiments are shown. In one embodiment, facet-edge signals are used to track the facets. A processor retrieves a predetermined frequency scaling factor appropriate for each facet. In the other embodiment, a holographic disk carries an auxiliary data track. The track has timing indicia with spatial frequencies dependent upon the focal length of the adjacent facet. The timing indicia are used to control the output of a voltage controlled oscillator in a circuit including a phase locked loop.
    Type: Grant
    Filed: December 8, 1986
    Date of Patent: January 24, 1989
    Assignee: International Business Machines Corporation
    Inventors: Eric C. Broockman, Robert T. Cato, William D. Gregory, Jr., George J. Laurer
  • Patent number: 4493039
    Abstract: Pictorial images of selected volume elements of materials are generated by a contactless, non-destructive, substantially hazard free tomographic technique in which the material is brought within the influence of a relatively low-strength electromagnetic field and subjected to plural preselected frequencies to provide output data which is used to generate an image reflective of the magnetic and/or electric and/or conductance properties of the selected volume elements. This data has a high volume information content which enables accurate and reproducible identification of the material under investigation. The technique has application in the medical diagnostic field such as for example in aiding in the detection of small areas of cancerous tissue present in a larger mass of healthy tissue.
    Type: Grant
    Filed: May 6, 1980
    Date of Patent: January 8, 1985
    Assignee: President and Directors of Georgetown University
    Inventor: William D. Gregory
  • Patent number: 4370611
    Abstract: The non-linear conductance and capacitance characteristics of electrically non-homogenous materials over a given frequency range are used to identify and analyze such materials.
    Type: Grant
    Filed: April 9, 1979
    Date of Patent: January 25, 1983
    Assignee: Georgetown University
    Inventors: William D. Gregory, Luigi Morelli
  • Patent number: 4263551
    Abstract: The type of conductor, its property, and if a metal, its type and cross-sectional area can be obtained from measurements made at different frequencies for the amount of unbalance created in a previously balanced stable coil detection system. The true resistive component is accurately measured and thus reflects only the voltage loss attributable to eddy currents caused by introduction of the test sample to the coil system. This voltage divided by corresponding applied frequency gives a curve which peaks at a frequency dependent upon type of conductor. For a metal this peak frequency is proportional to the samples resistivity divided by its cross-sectional area.
    Type: Grant
    Filed: January 20, 1978
    Date of Patent: April 21, 1981
    Assignee: Georgetown University
    Inventors: William D. Gregory, Larry H. Capots, James P. George, Richard Janik