Abstract: The present disclosure provides compositions that inhibit the SH2-containing inositol 5?phosphatase (SHIP) as well as methods using such composition for use in treating or ameliorating the effects of a medical condition in a subject. For examples, compositions including the general formula as disclosed herein are suitable for use herein.

Abstract: A control apparatus for an apparatus that cleans the drum of a ready mixed concrete truck includes a CAN-bus control system that includes a nozzle lance position encoder, a boom position encoder, a human-machine interface, a programmable logic controller, and monitors for an engine, hydraulic valves, and pressure sensors. The nozzle lance position encoder includes a rotary encoder, a bi-directional motor, a nozzle lance including a nozzle adapted to discharge water under high pressure, and a swivel assembly to which the nozzle lance is mounted for reciprocating motion. The programmable logic controller enables an operator to control the range of oscillation of the nozzle lance by inputting a desired range of oscillation into the programmable logic controller. An operator can also control extension and retraction of an elongate boom by inputting a desired rate of extension and retraction into the programmable logic controller.