Abstract: Embodiments of golf club heads, golf clubs, and methods to manufacture golf club heads and golf clubs are described herein. In one example, a golf club head includes a body portion with a front opening and a back opening, a face portion closing the front opening, and a back cover portion that closes the back opening and includes at least 50% of the total area of the back portion, a first port, and a second port. A first mass portion and a second mass portion engage the first port and the second port to close the first port and a second port, respectively. The first mass portion and the second mass portion each includes a material with a greater density than the material of the body portion and the material of the back cover portion. Other examples and embodiments may be described and claimed.

Abstract: A portable lighting device control module configured to intuitively adjust lighting operations of a portable lighting device by interpreting real-time user gestures and external conditions of the portable lighting device to modify lighting operations in response thereto.

Abstract: A portable lighting device control module configured to intuitively adjust lighting operations of a portable lighting device by interpreting real-time user gestures and external conditions of the portable lighting device to modifying lighting operations in response thereto.

Abstract: A portable lighting device control module configured to intuitively adjust lighting operations of a portable lighting device by interpreting real-time user gestures and external conditions of the portable lighting device to modifying lighting operations in response thereto.

Abstract: A portable lighting device control module configured to intuitively adjust lighting operations of a portable lighting device by interpreting real-time user gestures and external conditions of the portable lighting device to modifying lighting operations in response thereto.

Abstract: A portable lighting device control module configured to intuitively adjust lighting operations of a portable lighting device by interpreting real-time user gestures and external conditions of the portable lighting device to modifying lighting operations in response thereto.

Abstract: A portable lighting device control module configured to intuitively adjust lighting operations of a portable lighting device by interpreting real-time user gestures and external conditions of the portable lighting device to modifying lighting operations in response thereto.

Abstract: Human cancer is caused by the accumulation of mutations in oncogenes and tumor suppressor genes. To catalogue the genetic changes that occur during tumorigenesis, we isolated DNA from 11 breast and 11 colorectal tumors and determined the sequences of the genes in the Reference Sequence database in these samples. Based on analysis of exons representing 20,857 transcripts from 18,191 genes, we conclude that the genomic landscapes of breast and colorectal cancers are composed of a handful of commonly mutated gene “mountains” and a much larger number of gene “hills” that are mutated at low frequency. We describe statistical and bioinformatic tools that may help identify mutations with a role in tumorigenesis. These results have implications for understanding the nature and heterogeneity of human cancers and for using personal genomics for tumor diagnosis and therapy.

Abstract: Human cancer is caused by the accumulation of mutations in oncogenes and tumor suppressor genes. To catalogue the genetic changes that occur during tumorigenesis, we isolated DNA from 11 breast and 11 colorectal tumors and determined the sequences of the genes in the Reference Sequence database in these samples. Based on analysis of exons representing 20,857 transcripts from 18,191 genes, we conclude that the genomic landscapes of breast and colorectal cancers are composed of a handful of commonly mutated gene “mountains” and a much larger number of gene “hills” that are mutated at low frequency. We describe statistical and bioinformatic tools that may help identify mutations with a role in tumorigenesis. These results have implications for understanding the nature and heterogeneity of human cancers and for using personal genomics for tumor diagnosis and therapy.

Abstract: An insert plate is provided for mounting between the base mounting flange of a carburetor including a pair of air and fuel passages extending therethrough and an intake mounting boss having a corresponding pair of air and fuel passages formed therein with which the carburetor passages may be registered. The insert plate includes a pair of openings formed therethrough for registry with the carburetor and intake manifold air and fuel passages and defines an inlet extension of the manifold. A valve member is shiftably supported from the plate for movement between one of three positions, including a first position closing only one of the openings with the second opening unobstructed to the flow of fluid therethrough, a second position closing only the other of said openings and with said one opening unobstructed to the flow of fluid therethrough and a third out-of-the-way position with each of said openings unobstructed to the flow of fluid therethrough.