Patents by Inventor William D. Prevatt

William D. Prevatt has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Production of Bacillus entomotoxins in methylotrophic yeast
    Patent number: 5827684
    Abstract: A method for producing one or more Bacillus toxin polypeptides by culturing methylotrophic yeast cells which have a gene(s) capable of expressing the Bacillus toxin polypeptide(s) in such cells under conditions that the gene(s) is/are transcribed is provided. The toxin polypeptide encoding segment of the gene(s) has a G+C content of about 40%-55%, and preferably comprises methylotrophic yeast codons. The preferred species of yeast for expressing such synthetic Bacillus toxin gene(s) is Pichia pastoris. Bacillus toxin polypeptides encoded by synthetic genes are expressed at high levels in transformed methylotrophic yeast cells. The toxin expressing cells may be administered as live cells or heat-killed whole cells to provide an insecticidal composition for killing susceptible insect larvae.
    Type: Grant
    Filed: April 19, 1994
    Date of Patent: October 27, 1998
    Assignee: Research Corporation Technologies, Inc.
    Inventors: Kotikanyadanam Sreekrishna, William D. Prevatt, Gregory P. Thill, Geneva R. Davis, Patricia Koutz, Kathryn A. Barr, Sharon A. Hopkins
  • Expression of human serum albumin in Pichia pastoris
    Patent number: 5330901
    Abstract: A process for the production of HSA in Pichia pastoris cells comprising cultivating Pichia pastoris cells capable of expressing HSA at a pH of about 5.7 to about 6.4 contemporaneously with the expression of HSA.
    Type: Grant
    Filed: April 25, 1991
    Date of Patent: July 19, 1994
    Assignee: Research Corporation Technologies, Inc.
    Inventors: William D. Prevatt, Kotikanyadan Sreekrishna
  • Spheroplast fusions of Phaffia rhodozyma cells
    Patent number: 5212088
    Abstract: The present invention provides a process for the cell fusion of strains of Phaffia rhodozyma thereby providing novel strains of Phaffia rhodozyma.
    Type: Grant
    Filed: October 23, 1990
    Date of Patent: May 18, 1993
    Assignee: Phillips Petroleum Company
    Inventor: William D. Prevatt
  • Catalase-negative Pichia pastoris
    Patent number: 5204261
    Abstract: A novel strain of P. pastoris and an alcohol oxidase free of catalase activity produced therefrom is provided.
    Type: Grant
    Filed: April 24, 1991
    Date of Patent: April 20, 1993
    Assignee: Phillips Petroleum Company
    Inventors: William D. Prevatt, George T. Sperl
  • Selective conversion of cyano compounds to amides and carboxylic acids
    Patent number: 4629700
    Abstract: A process for producing aromatic compound having at least one cyano group and one amide group or carboxyl group which process comprises subjecting aromatic polynitrile compound containing no carboxyl groups in a simple medium to the action of one or more microorganisms which have a nitrilase system capable of selectively hydrolyzing one cyano group of the polynitrile.
    Type: Grant
    Filed: November 30, 1983
    Date of Patent: December 16, 1986
    Assignee: Standard Oil Company (Indiana)
    Inventors: William D. Prevatt, Cavit Akin, April J. Evans