Patents by Inventor William Dai
William Dai has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).
-
Patent number: 11953399Abstract: Pressure sensors having ring-tensioned membranes are disclosed. A tensioning ring is bonded to a membrane in a manner that results in the tensioning ring applying a tensile force to the membrane, flattening the membrane and reducing or eliminating defects that may have occurred during production. The membrane is bonded to the sensor housing at a point outside the tensioning ring, preventing the process of bonding the membrane to the housing from introducing defects into the tensioned portion of the membrane. A dielectric may be introduced into the gap between the membrane and the counter electrode in a capacitive pressure sensor, resulting in an improved dynamic range.Type: GrantFiled: April 7, 2023Date of Patent: April 9, 2024Assignee: THE ALFRED E. MANN FOUNDATION FOR SCIENTIFIC RESEARCHInventors: Siegmar Schmidt, William A. Dai, Boon Khai Ng
-
Publication number: 20230243711Abstract: Pressure sensors having ring-tensioned membranes are disclosed. A tensioning ring is bonded to a membrane in a manner that results in the tensioning ring applying a tensile force to the membrane, flattening the membrane and reducing or eliminating defects that may have occurred during production. The membrane is bonded to the sensor housing at a point outside the tensioning ring, preventing the process of bonding the membrane to the housing from introducing defects into the tensioned portion of the membrane. A dielectric may be introduced into the gap between the membrane and the counter electrode in a capacitive pressure sensor, resulting in an improved dynamic range.Type: ApplicationFiled: April 7, 2023Publication date: August 3, 2023Inventors: Siegmar SCHMIDT, William A. DAI, Boon Khai NG
-
Publication number: 20230241393Abstract: An electrode lead comprises an electrically insulative cuff body and at least three axially aligned electrode contacts circumferentially disposed along the inner surface of the cuff body when in the furled state. The electrode contacts may be circumferentially disposed around a nerve, and an electrical pulse train may be delivered to the electrode contacts thereby stimulating the nerve to treat obstructive sleep apnea. The electrical pulse train may be one that pre-conditions peripherally located nerve fascicles to not be stimulated, while stimulating centrally located nerve fascicles. A feedback mechanism can be used to titrate electrode contacts and electrical pulse train to the patient. A sensor that is affixed to the case of a neurostimulator can be used to measure physiological artifacts of respiration, and a motion detector can be used to sense tapping of the neurostimulator to toggle the neurostimulator between an ON position and an OFF position.Type: ApplicationFiled: April 6, 2023Publication date: August 3, 2023Applicant: THE ALFRED E. MANN FOUNDATION FOR SCIENTIFIC RESEARCHInventors: Harshit Suri, Joseph L. Calderon, Gregory Frederick Molnar, George S. Goding, JR., Alanie Atyabi, Siegmar Schmidt, William Dai, Brian Dearden, Desmond B. Keenan
-
Patent number: 11654284Abstract: An electrode lead comprises an electrically insulative cuff body and at least three axially aligned electrode contacts circumferentially disposed along the inner surface of the cuff body when in the furled state. The electrode contacts may be circumferentially disposed around a nerve, and an electrical pulse train may be delivered to the electrode contacts thereby stimulating the nerve to treat obstructive sleep apnea. The electrical pulse train may be one that pre-conditions peripherally located nerve fascicles to not be stimulated, while stimulating centrally located nerve fascicles. A feedback mechanism can be used to titrate electrode contacts and electrical pulse train to the patient. A sensor that is affixed to the case of a neurostimulator can be used to measure physiological artifacts of respiration, and a motion detector can be used to sense tapping of the neurostimulator to toggle the neurostimulator between an ON position and an OFF position.Type: GrantFiled: October 29, 2020Date of Patent: May 23, 2023Assignee: THE ALFRED E. MANN FOUNDATION FOR SCIENTIFIC RESEARCHInventors: Harshit Suri, Joseph L. Calderon, Gregory Frederick Molnar, George S. Goding, Jr., Alanie Atyabi, Siegmar Schmidt, William Dai, Brian Dearden, Desmond B. Keenan
-
Patent number: 11642529Abstract: An electrode lead comprises an electrically insulative cuff body and at least three axially aligned electrode contacts circumferentially disposed along the inner surface of the cuff body when in the furled state. The electrode contacts may be circumferentially disposed around a nerve, and an electrical pulse train may be delivered to the electrode contacts thereby stimulating the nerve to treat obstructive sleep apnea. The electrical pulse train may be one that pre-conditions peripherally located nerve fascicles to not be stimulated, while stimulating centrally located nerve fascicles. A feedback mechanism can be used to titrate electrode contacts and electrical pulse train to the patient. A sensor that is affixed to the case of a neurostimulator can be used to measure physiological artifacts of respiration, and a motion detector can be used to sense tapping of the neurostimulator to toggle the neurostimulator between an ON position and an OFF position.Type: GrantFiled: November 6, 2020Date of Patent: May 9, 2023Assignee: THE ALFRED E. MANN FOUNDATION FOR SCIENTIFIC RESEARCHInventors: Harshit Suri, Joseph L. Calderon, Gregory Frederick Molnar, George S. Goding, Jr., Alanie Atyabi, Siegmar Schmidt, William Dai, Brian Dearden, Desmond B. Keenan
-
Patent number: 11638826Abstract: An electrode lead comprises an electrically insulative cuff body and at least three axially aligned electrode contacts circumferentially disposed along the inner surface of the cuff body when in the furled state. The electrode contacts may be circumferentially disposed around a nerve, and an electrical pulse train may be delivered to the electrode contacts thereby stimulating the nerve to treat obstructive sleep apnea. The electrical pulse train may be one that pre-conditions peripherally located nerve fascicles to not be stimulated, while stimulating centrally located nerve fascicles. A feedback mechanism can be used to titrate electrode contacts and electrical pulse train to the patient. A sensor that is affixed to the case of a neurostimulator can be used to measure physiological artifacts of respiration, and a motion detector can be used to sense tapping of the neurostimulator to toggle the neurostimulator between an ON position and an OFF position.Type: GrantFiled: March 9, 2020Date of Patent: May 2, 2023Assignee: THE ALFRED E. MANN FOUNDATION FOR SCIENTIFIC RESEARCHInventors: Harshit Suri, Joseph L. Calderon, Gregory Frederick Molnar, George S. Goding, Jr., Alanie Atyabi, Siegmar Schmidt, William Dai, Brian Dearden, Desmond B. Keenan
-
Patent number: 11630013Abstract: Pressure sensors having ring-tensioned membranes are disclosed. A tensioning ring is bonded to a membrane in a manner that results in the tensioning ring applying a tensile force to the membrane, flattening the membrane and reducing or eliminating defects that may have occurred during production. The membrane is bonded to the sensor housing at a point outside the tensioning ring, preventing the process of bonding the membrane to the housing from introducing defects into the tensioned portion of the membrane. A dielectric may be introduced into the gap between the membrane and the counter electrode in a capacitive pressure sensor, resulting in an improved dynamic range.Type: GrantFiled: July 28, 2020Date of Patent: April 18, 2023Assignee: THE ALFRED E. MANN FOUNDATION FOR SCIENTIFIC RESEARCHInventors: Siegmar Schmidt, William A. Dai, Boon Khai Ng
-
Patent number: 10981000Abstract: An electrode lead comprises an elongated lead body, at least one lead connector terminal affixed to the proximal end of the lead body, and an electrically insulative cuff body affixed to the distal end of the lead body. The cuff body is configured for being circumferentially disposed around a nerve. The cuff body comprises cutouts, slits, a wrinkled portion, a thin stretchable portion, and/or a serpentine strap, which increases that increase the expandability of the cuff body when disposed around the nerve. The electrode lead further comprises at least one electrode contact affixed to the cuff body, and at least one electrical conductor extending through the lead body between the at least one lead connector terminal and the electrode contact(s). If the cuff body comprises cutouts or slits, the electrode lead can further comprise a thin stretchable film affixed to the cuff body over cutouts or slits.Type: GrantFiled: April 30, 2018Date of Patent: April 20, 2021Assignee: THE ALFRED E. MANN FOUNDATION FOR SCIENTIFIC RESEARCHInventors: Boon Khai Ng, William Dai
-
Publication number: 20210052893Abstract: An electrode lead comprises an electrically insulative cuff body and at least three axially aligned electrode contacts circumferentially disposed along the inner surface of the cuff body when in the furled state. The electrode contacts may be circumferentially disposed around a nerve, and an electrical pulse train may be delivered to the electrode contacts thereby stimulating the nerve to treat obstructive sleep apnea. The electrical pulse train may be one that pre-conditions peripherally located nerve fascicles to not be stimulated, while stimulating centrally located nerve fascicles. A feedback mechanism can be used to titrate electrode contacts and electrical pulse train to the patient. A sensor that is affixed to the case of a neurostimulator can be used to measure physiological artifacts of respiration, and a motion detector can be used to sense tapping of the neurostimulator to toggle the neurostimulator between an ON position and an OFF position.Type: ApplicationFiled: November 6, 2020Publication date: February 25, 2021Applicant: THE ALFRED E. MANN FOUNDATION FOR SCIENTIFIC RESEARCHInventors: Harshit Suri, Joseph L. Cakleron, Gregory Frederick Moinar, George S. Goding, JR., Alanie Atyabi, Siegmar Schmidt, William Dai, Brian Dearden, Desmond B. Keenan
-
Publication number: 20210038889Abstract: An electrode lead comprises an electrically insulative cuff body and at least three axially aligned electrode contacts circumferentially disposed along the inner surface of the cuff body when in the furled state. The electrode contacts may be circumferentially disposed around a nerve, and an electrical pulse train may be delivered to the electrode contacts thereby stimulating the nerve to treat obstructive sleep apnea. The electrical pulse train may be one that pre-conditions peripherally located nerve fascicles to not be stimulated, while stimulating centrally located nerve fascicles. A feedback mechanism can be used to titrate electrode contacts and electrical pulse train to the patient. A sensor that is affixed to the case of a neurostimulator can be used to measure physiological artifacts of respiration, and a motion detector can be used to sense tapping of the neurostimulator to toggle the neurostimulator between an ON position and an OFF position.Type: ApplicationFiled: October 29, 2020Publication date: February 11, 2021Applicant: THE ALFRED E. MANN FOUNDATION FOR SCIENTIFIC RESEARCHInventors: Harshit Suri, Joseph L. Calderon, Gregory Frederick Molnar, George S. Goding, JR., Alanie Atyabi, Siegmar Schmidt, William Dai, Brian Dearden, Desmond B. Keenan
-
Publication number: 20200368526Abstract: An electrode lead comprises an electrically insulative cuff body and at least three axially aligned electrode contacts circumferentially disposed along the inner surface of the cuff body when in the furled state. The electrode contacts may be circumferentially disposed around a nerve, and an electrical pulse train may be delivered to the electrode contacts thereby stimulating the nerve to treat obstructive sleep apnea. The electrical pulse train may be one that pre-conditions peripherally located nerve fascicles to not be stimulated, while stimulating centrally located nerve fascicles. A feedback mechanism can be used to titrate electrode contacts and electrical pulse train to the patient. A sensor that is affixed to the case of a neurostimulator can be used to measure physiological artifacts of respiration, and a motion detector can be used to sense tapping of the neurostimulator to toggle the neurostimulator between an ON position and an OFF position.Type: ApplicationFiled: August 13, 2020Publication date: November 26, 2020Applicant: THE ALFRED E. MANN FOUNDATION FOR SCIENTIFIC RESEARCHInventors: Harshit Suri, Joseph L. Calderon, Gregory Frederick Molnar, George S. Goding, JR., Alanie Atyabi, Siegmar Schmidt, William Dai, Brian Dearden, Desmond B. Keenan
-
Publication number: 20200355567Abstract: Pressure sensors having ring-tensioned membranes are disclosed. A tensioning ring is bonded to a membrane in a manner that results in the tensioning ring applying a tensile force to the membrane, flattening the membrane and reducing or eliminating defects that may have occurred during production. The membrane is bonded to the sensor housing at a point outside the tensioning ring, preventing the process of bonding the membrane to the housing from introducing defects into the tensioned portion of the membrane. A dielectric may be introduced into the gap between the membrane and the counter electrode in a capacitive pressure sensor, resulting in an improved dynamic range.Type: ApplicationFiled: July 28, 2020Publication date: November 12, 2020Inventors: Siegmar SCHMIDT, William A. DAI, Boon Khai NG
-
Patent number: 10739218Abstract: Pressure sensors having ring-tensioned membranes are disclosed. A tensioning ring is bonded to a membrane in a manner that results in the tensioning ring applying a tensile force to the membrane, flattening the membrane and reducing or eliminating defects that may have occurred during production. The membrane is bonded to the sensor housing at a point outside the tensioning ring, preventing the process of bonding the membrane to the housing from introducing defects into the tensioned portion of the membrane. A dielectric may be introduced into the gap between the membrane and the counter electrode in a capacitive pressure sensor, resulting in an improved dynamic range.Type: GrantFiled: April 11, 2017Date of Patent: August 11, 2020Assignee: THE ALFRED E. MANN FOUNDATION FOR SCIENTIFIC RESEARCHInventors: Siegmar Schmidt, William A. Dai, Boon Khai Ng
-
Publication number: 20200206501Abstract: An electrode lead comprises an electrically insulative cuff body and at least three axially aligned electrode contacts circumferentially disposed along the inner surface of the cuff body when in the furled state. The electrode contacts may be circumferentially disposed around a nerve, and an electrical pulse train may be delivered to the electrode contacts thereby stimulating the nerve to treat obstructive sleep apnea. The electrical pulse train may be one that pre-conditions peripherally located nerve fascicles to not be stimulated, while stimulating centrally located nerve fascicles. A feedback mechanism can be used to titrate electrode contacts and electrical pulse train to the patient. A sensor that is affixed to the case of a neurostimulator can be used to measure physiological artifacts of respiration, and a motion detector can be used to sense tapping of the neurostimulator to toggle the neurostimulator between an ON position and an OFF position.Type: ApplicationFiled: March 9, 2020Publication date: July 2, 2020Applicant: THE ALFRED E. MANN FOUNDATION FOR SCIENTIFIC RESEARCHInventors: Harshit Suri, Joseph L Calderon, Gregory Frederick Molnar, George S. Goding, JR., Alanie Atyabi, Siegmar Schmidt, William Dai, Brian Dearden, Desmond B. Keenan
-
Publication number: 20190143110Abstract: An electrode lead comprises an electrically insulative cuff body and at least three axially aligned electrode contacts circumferentially disposed along the inner surface of the cuff body when in the furled state. The electrode contacts may be circumferentially disposed around a nerve, and an electrical pulse train may be delivered to the electrode contacts thereby stimulating the nerve to treat obstructive sleep apnea. The electrical pulse train may be one that pre-conditions peripherally located nerve fascicles to not be stimulated, while stimulating centrally located nerve fascicles. A feedback mechanism can be used to titrate electrode contacts and electrical pulse train to the patient. A sensor that is affixed to the case of a neurostimulator can be used to measure physiological artifacts of respiration, and a motion detector can be used to sense tapping of the neurostimulator to toggle the neurostimulator between an ON position and an OFF position.Type: ApplicationFiled: January 11, 2019Publication date: May 16, 2019Applicant: THE ALFRED E. MANN FOUNDATION FOR SCIENTIFIC RESEARCHInventors: Harshit Suri, Joseph L. Calderon, Gregory Frederick Molnar, George S. Goding, JR., Alanie Atyabi, Siegmar Schmidt, William Dai, Brian Dearden, Desmond B. Keenan
-
Publication number: 20180318578Abstract: An electrode lead comprises an elongated lead body, at least one lead connector terminal affixed to the proximal end of the lead body, and an electrically insulative cuff body affixed to the distal end of the lead body. The cuff body is configured for being circumferentially disposed around a nerve. The cuff body comprises cutouts, slits, a wrinkled portion, a thin stretchable portion, and/or a serpentine strap, which increases that increase the expandability of the cuff body when disposed around the nerve. The electrode lead further comprises at least one electrode contact affixed to the cuff body, and at least one electrical conductor extending through the lead body between the at least one lead connector terminal and the electrode contact(s). If the cuff body comprises cutouts or slits, the electrode lead can further comprise a thin stretchable film affixed to the cuff body over cutouts or slits.Type: ApplicationFiled: April 30, 2018Publication date: November 8, 2018Applicant: THE ALFRED E. MANN FOUNDATION FOR SCIENTIFIC RESEARCHInventors: Boon Khai Ng, William Dai
-
Publication number: 20180221660Abstract: An electrode lead comprises an electrically insulative cuff body and at least three axially aligned electrode contacts circumferentially disposed along the inner surface of the cuff body when in the furled state. The electrode contacts may be circumferentially disposed around a nerve, and an electrical pulse train may be delivered to the electrode contacts thereby stimulating the nerve to treat obstructive sleep apnea. The electrical pulse train may be one that pre-conditions peripherally located nerve fascicles to not be stimulated, while stimulating centrally located nerve fascicles. A feedback mechanism can be used to titrate electrode contacts and electrical pulse train to the patient. A sensor that is affixed to the case of a neurostimulator can be used to measure physiological artifacts of respiration, and a motion detector can be used to sense tapping of the neurostimulator to toggle the neurostimulator between an ON position and an OFF position.Type: ApplicationFiled: January 31, 2018Publication date: August 9, 2018Applicant: THE ALFRED E. MANN FOUNDATION FOR SCIENTIFIC RESEARCHInventors: Harshit Suri, Joseph L. Calderon, Gregory Frederick Molnar, George S. Goding, Jr., Alanie Atyabi, Siegmar Schmidt, William Dai, Brian Dearden, Desmond B. Keenan
-
Publication number: 20170292887Abstract: Pressure sensors having ring-tensioned membranes are disclosed. A tensioning ring is bonded to a membrane in a manner that results in the tensioning ring applying a tensile force to the membrane, flattening the membrane and reducing or eliminating defects that may have occurred during production. The membrane is bonded to the sensor housing at a point outside the tensioning ring, preventing the process of bonding the membrane to the housing from introducing defects into the tensioned portion of the membrane. A dielectric may be introduced into the gap between the membrane and the counter electrode in a capacitive pressure sensor, resulting in an improved dynamic range.Type: ApplicationFiled: April 11, 2017Publication date: October 12, 2017Inventors: Siegmar Schmidt, William A. Dai, Boon Khai NG
-
Publication number: 20170202513Abstract: An implantable pressure sensor device and devices incorporating an implantable pressure sensor are disclosed. The implantable pressure sensor may include a housing with a deflectable wall, and may be incorporated into a housing of an implantable medical device such as an implantable pulse generator. The pressure sensor may monitor respiration by measuring the deflection of the deflectable wall caused by expansion of the thoracic wall or ribcage.Type: ApplicationFiled: December 9, 2016Publication date: July 20, 2017Applicant: THE ALFRED E. MANN FOUNDATION FOR SCIENTIFIC RESEARCHInventors: Siegmar Schmidt, William A. Dai
-
Publication number: 20160354603Abstract: An upper airway stimulator for treating obstructive sleep apnea is described. In some embodiments, the upper airway stimulator monitors the phase difference between ribcage expansion and abdomen expansion to detect apneic events and stimulates to alleviate those events. In some embodiments, the upper airway stimulator applies primary stimulation when an apneic event is not detected and secondary stimulation when an apneic event is detected. In some embodiments, the upper airway stimulator applies primary stimulation when the patient is not in an apneic position and secondary stimulation when the patient is in an apneic position.Type: ApplicationFiled: April 7, 2016Publication date: December 8, 2016Applicant: THE ALFRED E. MANN FOUNDATION FOR SCIENTIFIC RESEARCHInventors: DESMOND B. KEENAN, MORTEN HANSEN, BRIAN R. DEARDEN, SIEGMAR SCHMIDT, WILLIAM A. DAI