Abstract: Marker systems and methods for implanting a marker are provided. In one embodiment, a marker system can include an elongate cannulated tube, a marker capsule, and a driver member. The cannulated tube can have a piercing feature arranged at a distal end thereof that is configured to create a working portal through tissue such that fluid can be delivered into the tissue to form a bleb. The marker capsule can be removably disposed within the lumen of the cannulated tube. The marker capsule can include a transmission antenna, and an arranging feature disposed on an external surface configured to facilitate rotation of the marker capsule within the bleb. The driver member can be arranged within the lumen of the cannulated tube proximal to the marker capsule. The drive member can be configured to advance distally to displace the marker capsule through the working portal and into the bleb.