Abstract: A venous valve with a frame and a cover on the frame for unidirectional flow of a liquid through the valve.

Abstract: A filter system, comprising an elongate filter body defining a lumen and having a proximal end and a distal end. A valve can be provided defining a lumen and having a reversibly sealable opening for unidirectional flow of a fluid through the lumen. The valve can be adjoined proximal the distal end of the elongate filter body, wherein the elongate filter body filters the unidirectional flow of the fluid passing through the lumen of the valve and the lumen of the elongate filter body.

Abstract: A catheter including an elongate body, a first cutting head and a second cutting head both having a blade, where the blades moves relative each other to provide a shearing action for cardiac tissue. The catheter can further include a stent positioned over an inflatable balloon, where the inflatable balloon can deploy the expandable stent over sheared cardiac tissue. The catheter can further be included in a system having a sheath, where at least a part of the catheter resides in the lumen of the sheath. The sheath further includes a cardiac valve and an expandable filter. The sheath can move relative the cardiac valve and the expandable filter to deploy the cardiac valve and at least a portion of the expandable filter proximal the inflatable balloon and the expandable stent.

Abstract: The present invention is directed to medical devices that contain at least one tissue contacting surface that is configured to undergo a variation in surface charge in response to a time-dependent signal. Such a variation in surface charge is provided, for example, to enhance or inhibit cellular growth adjacent to, on, or within the at least one tissue contacting surface.

Abstract: A cardiac valve with a support frame having a first end member and a second end member opposing the first end member in a substantially fixed distance relationship, and a cover extending over the support frame to allow for unidirectional flow of a liquid through the valve.

Abstract: Occluded vasculature such as occluded arterial vasculature can be recanalized using a device that is configured to penetrate an occlusion, while limiting a distance that said penetration structure can extend in order to limit inadvertent vascular damage. The device can include an elongate sheath and a stylet disposed within the elongate sheath. The elongate sheath and the stylet can include, in combination, an engagement section that is configured to limit relative axial movement between the elongate sheath and the stylet.

Abstract: Apparatus and methods for forming a conduit through an infarcted region where the conduit is in fluid communication with a supply of oxygenated blood and the venous vasculature and flowing oxygenated blood from the supply of oxygenated blood through the conduit and to the venous vasculature.