Patents by Inventor William Dunbar

William Dunbar has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Patent number: 9863912
    Abstract: Provided is a device comprising an upper chamber, a middle chamber and a lower chamber, wherein the upper chamber is in communication with the middle chamber through a first pore, and the middle chamber is in communication with the lower chamber through a second pore, wherein the first pore and second pore are about 1 nm to about 100 nm in diameter, and are about 10 nm to about 1000 nm apart from each other, and wherein each of the chambers comprises an electrode for connecting to a power supply. Methods of using the device are also provided, in particular for sequencing a polynucleotide.
    Type: Grant
    Filed: November 29, 2014
    Date of Patent: January 9, 2018
    Assignee: The Regents of the University of California
    Inventors: William Dunbar, Jungsuk Kim
  • Publication number: 20170269034
    Abstract: Provided is a device comprising a channel through and defined by a plurality of layers surrounding the channel, the channel connecting a first and a second chambers separated by the plurality of layers, wherein the plurality of layers comprise a first layer, a second layer; and a conductive middle layer disposed between the first and second layers, wherein the channel comprises (a) a first region defined by the first layer, denoted as an inlet, that is about 0.5 nm to about 100 nm in diameter and (b) a second region defined by the second layer, denoted as an outlet, wherein the inlet and the outlet are about 10 nm to about 1000 nm apart from each other, and wherein the first and second chambers and the middle layer are connected to a power supply. Also provided are methods of preparing and using the device, in particular for nucleic acid sequencing.
    Type: Application
    Filed: May 26, 2017
    Publication date: September 21, 2017
    Applicants: The Regents of the University of California, Brigham Young University
    Inventors: William Dunbar, Holger Schmidt, Aaron Hawkins
  • Patent number: 9696277
    Abstract: Provided is a device comprising a channel through and defined by a plurality of layers surrounding the channel, the channel connecting a first and a second chambers separated by the plurality of layers, wherein the plurality of layers comprise a first layer, a second layer; and a conductive middle layer disposed between the first and second layers, wherein the channel comprises (a) a first region defined by the first layer, denoted as an inlet, that is about 0.5 nm to about 100 nm in diameter and (b) a second region defined by the second layer, denoted as an outlet, wherein the inlet and the outlet are about 10 nm to about 1000 nm apart from each other, and wherein the first and second chambers and the middle layer are connected to a power supply. Also provided are methods of preparing and using the device, in particular for nucleic acid sequencing.
    Type: Grant
    Filed: November 13, 2012
    Date of Patent: July 4, 2017
    Assignees: The Regents of the University of California, Brigham Young University
    Inventors: William Dunbar, Holger Schmidt, Aaron Hawkins
  • Publication number: 20170145481
    Abstract: A multiplexed nanopore sensing network comprising an integrated and multiplexed network of patch clamp capacitive integrator-differentiator amplifiers with small feedback capacitors using pseudo-resistors.
    Type: Application
    Filed: February 4, 2017
    Publication date: May 25, 2017
    Applicant: The Regents of the University of California
    Inventors: Jungsuk Kim, William Dunbar
  • Patent number: 9650670
    Abstract: A polynucleotide sequencer comprising an integrated and multiplexed network of patch clamp capacitive integrator-differentiator amplifiers with small feedback capacitors using pseudo-resistors.
    Type: Grant
    Filed: October 28, 2013
    Date of Patent: May 16, 2017
    Assignee: The Regents of the University of California
    Inventors: Jungsuk Kim, William Dunbar
  • Publication number: 20160227718
    Abstract: The present invention provides a new and useful (i) plant root feeding device (ii) plant root feeding system, (iii) method of feeding a plant, and (iv) method of manufacturing a plant root feeding device. The plant root feeding device comprises a fluid container (emitter) formed of semi permeable material that allows fluid to pass from the inside of the container to a plant root located in ground in proximity to the fluid container. The fluid container has a fluid inlet opening, and a fluid inlet tube is in fluid communication with the fluid inlet opening of the fluid container. The fluid inlet tube has a fixed, fluid sealed coupling to the fluid inlet opening of the fluid container, and the fluid container has a configuration that enables it to be located in ground in proximity to an in ground root system of a plant, and a permeability that enables fluid to pass from the inside of the container to the in ground root system of a plant in proximity to the fluid container.
    Type: Application
    Filed: February 11, 2015
    Publication date: August 11, 2016
    Inventors: John Matthews, William Dunbar
  • Publication number: 20150377856
    Abstract: A compensated patch-clamp system for polynucleotide sequencing and other applications.
    Type: Application
    Filed: June 24, 2015
    Publication date: December 31, 2015
    Applicant: THE REGENTS OF THE UNIVERSITY OF CALIFORNIA
    Inventors: William Dunbar, Kenneth Pedrotti, Jungsuk Kim
  • Publication number: 20150337367
    Abstract: A polynucleotide sequencer comprising an integrated and multiplexed network of patch clamp capacitive integrator-differentiator amplifiers with small feedback capacitors using pseudo-resistors.
    Type: Application
    Filed: October 28, 2013
    Publication date: November 26, 2015
    Inventors: Jungsuk Kim, William Dunbar
  • Patent number: 9101416
    Abstract: Spinal rod approximator for seating a stabilizing rod in a rod-receiving portion of a spinal implant and inserting closure mechanism is provided. In one embodiment, a spinal rod approximator is provided including a body with gripping branches, inserter shaft, threaded collar, and outer sleeve.
    Type: Grant
    Filed: October 21, 2010
    Date of Patent: August 11, 2015
    Assignee: DePuy Synthes Products, Inc.
    Inventors: William Dunbar, Jr., Christopher Ryan Rybicki, Ian Charles Burgess
  • Publication number: 20150160160
    Abstract: Provided is a device comprising an upper chamber, a middle chamber and a lower chamber, wherein the upper chamber is in communication with the middle chamber through a first pore, and the middle chamber is in communication with the lower chamber through a second pore, wherein the first pore and second pore are about 1 nm to about 100 nm in diameter, and are about 10 nm to about 1000 nm apart from each other, and wherein each of the chambers comprises an electrode for connecting to a power supply. Methods of using the device are also provided, in particular for sequencing a polynucleotide.
    Type: Application
    Filed: November 29, 2014
    Publication date: June 11, 2015
    Applicant: The Regents of the University of California
    Inventors: William Dunbar, Jungsuk Kim
  • Patent number: 8961763
    Abstract: Provided is a device comprising an upper chamber, a middle chamber and a lower chamber, wherein the upper chamber is in communication with the middle chamber through a first pore, and the middle chamber is in communication with the lower chamber through a second pore, wherein the first pore and second pore are about 1 nm to about 100 nm in diameter, and are about 10 nm to about 1000 nm apart from each other, and wherein each of the chambers comprises an electrode for connecting to a power supply. Methods of using the device are also provided, in particular for sequencing a polynucleotide.
    Type: Grant
    Filed: July 18, 2012
    Date of Patent: February 24, 2015
    Assignee: The Regents of the University of California
    Inventors: William Dunbar, Jungsuk Kim
  • Publication number: 20140318964
    Abstract: Provided is a device comprising a channel through and defined by a plurality of layers surrounding the channel, the channel connecting a first and a second chambers separated by the plurality of layers, wherein the plurality of layers comprise a first layer, a second layer; and a conductive middle layer disposed between the first and second layers, wherein the channel comprises (a) a first region defined by the first layer, denoted as an inlet, that is about 0.5 nm to about 100 nm in diameter and (b) a second region defined by the second layer, denoted as an outlet, wherein the inlet and the outlet are about 10 nm to about 1000 nm apart from each other, and wherein the first and second chambers and the middle layer are connected to a power supply. Also provided are methods of preparing and using the device, in particular for nucleic acid sequencing.
    Type: Application
    Filed: November 13, 2012
    Publication date: October 30, 2014
    Applicants: Brigham Young University, The Regents of the University of California
    Inventors: William Dunbar, Holger Schmidt, Aaron Hawkins
  • Patent number: 8864772
    Abstract: Various methods and devices are provided for implanting a motion segment repair system. In particular, exemplary methods and devices are provided for implanting a spinal disc implant and/or a PDS device using a posterior surgical approach, including methods and devices for distracting adjacent vertebrae using a posterior surgical approach, methods and devices for posteriorly introducing a spinal implant into a disc space between adjacent vertebrae, and methods and devices for coupling a PDS device to the adjacent vertebrae to provide a complete motion segment repair system that is implanted using a posterior surgical approach.
    Type: Grant
    Filed: January 20, 2011
    Date of Patent: October 21, 2014
    Assignee: DePuy Synthes Products, LLC
    Inventors: Dominique Verhulst, Amie Borgstrom, Charles M. Bartish, Jr., John Riley Hawkins, SeungKyu Daniel Kwak, William Dunbar, Katherine Torres
  • Patent number: 8709043
    Abstract: Various methods and devices for replacing damaged, injured, diseased, or otherwise unhealthy posterior elements, such as the facet joints, the lamina, the posterior ligaments, and/or other features of a patient's spinal column, are provided. In one exemplary embodiment, the methods and devices are effective to mimic the natural function of the spine by allowing flexion, extension, and lateral bending of the spine, while substantially restricting posterior-anterior shear and rotation of the spine.
    Type: Grant
    Filed: January 18, 2011
    Date of Patent: April 29, 2014
    Assignee: DePuy Spine, Inc.
    Inventors: SeungKyu Daniel Kwak, John Riley Hawkins, Amie Borgstrom, William Dunbar
  • Publication number: 20130341192
    Abstract: A compensated patch-clamp system for polynucleotide sequencing and other applications.
    Type: Application
    Filed: July 18, 2012
    Publication date: December 26, 2013
    Applicant: THE REGENTS OF THE UNIVERSITY OF CALIFORNIA
    Inventors: William Dunbar, Jungsuk Kim, Kenneth Pedrotti
  • Publication number: 20130233709
    Abstract: Provided is a device comprising an upper chamber, a middle chamber and a lower chamber, wherein the upper chamber is in communication with the middle chamber through a first pore, and the middle chamber is in communication with the lower chamber through a second pore, wherein the first pore and second pore are about 1 nm to about 100 nm in diameter, and are about 10 nm to about 1000 nm apart from each other, and wherein each of the chambers comprises an electrode for connecting to a power supply. Methods of using the device are also provided, in particular for sequencing a polynucleotide.
    Type: Application
    Filed: July 18, 2012
    Publication date: September 12, 2013
    Applicant: THE REGENT OF THE UNIVERSITY OF CALIFORNIA
    Inventors: William Dunbar, Jungsuk Kim
  • Patent number: 8092496
    Abstract: Various methods and devices for replacing damaged, injured, diseased, or otherwise unhealthy posterior elements, such as the facet joints, the lamina, the posterior ligaments, and/or other features of a patient's spinal column, are provided. In certain exemplary embodiments, a four bar linkage mechanism can be used to construct spinal stabilization devices and methods for restoring function to adjacent vertebrae. In particular, spinal stabilization devices can be provided that kinematically form a four-bar linkage mechanism with adjacent vertebrae and a disc or other element disposed between the adjacent vertebrae.
    Type: Grant
    Filed: June 21, 2005
    Date of Patent: January 10, 2012
    Assignee: DePuy Spine, Inc.
    Inventors: SeungKyu Daniel Kwak, Amie Borgstrom, John Riley Hawkins, William Dunbar
  • Patent number: 8070783
    Abstract: Various methods and devices for replacing damaged, injured, diseased, or otherwise unhealthy posterior elements, such as the facet joints, the lamina, the posterior ligaments, and/or other features of a patient's spinal column, are provided. In one exemplary embodiment, the methods and devices are effective to mimic the natural function of the spine by allowing flexion, extension, and lateral bending of the spine, while substantially restricting posterior-anterior shear and rotation of the spine.
    Type: Grant
    Filed: August 18, 2010
    Date of Patent: December 6, 2011
    Assignee: DePuy Spine, Inc.
    Inventors: SeungKyu Daniel Kwak, John Riley Hawkins, Amie Borgstrom, William Dunbar
  • Patent number: 7993376
    Abstract: Various methods and devices are provided for implanting a motion segment repair system. In particular, exemplary methods and devices are provided for implanting a spinal disc implant and/or a PDS device using a posterior surgical approach, including methods and devices for distracting adjacent vertebrae using a posterior surgical approach, methods and devices for posteriorly introducing a spinal implant into a disc space between adjacent vertebrae, and methods and devices for coupling a PDS device to the adjacent vertebrae to provide a complete motion segment repair system that is implanted using a posterior surgical approach.
    Type: Grant
    Filed: November 30, 2005
    Date of Patent: August 9, 2011
    Assignee: DePuy Spine, Inc.
    Inventors: Dominique Verhulst, Amie Borgstrom, Charles M. Bartish, Jr., John Riley Hawkins, SeungKyu Daniel Kwak, William Dunbar, Katherine Torres
  • Patent number: 7985244
    Abstract: A posterior stabilization device is provided for controlling movement between adjacent vertebrae. In one exemplary embodiment, the stabilization device can include one or more joints that rely on rotational or sliding movement to allow flexion of adjacent vertebrae, and that control extension, lateral bending, axial rotation, and anterior-posterior shear, preferably by providing one or more flexible connectors and/or a flexible central spacer for connecting to the adjacent superior and inferior vertebrae.
    Type: Grant
    Filed: September 27, 2005
    Date of Patent: July 26, 2011
    Assignee: DePuy Spine, Inc.
    Inventors: Amie Borgstrom, SeungKyu Daniel Kwak, Missoum Moumene, William Dunbar, John Riley Hawkins