Abstract: Superficially porous hybrid particles include hybrid solid cores that each contain an inorganic material and an organic material; and porous hybrid outer shells each include the inorganic and organic materials and having ordered pores, wherein the ordered pores have a median pore size ranges from about 15 to about 1000 ? with a pore size distribution (one standard deviation) of no more than 50% of the median pore size and produce at least one X-ray diffraction peak between 0.01° and 10° of a 2? scan range; wherein the particles have a median size range from about 0.5 ?m to about 100 ?m with a particle size distribution (one standard deviation) of no more than 15% of the median particle size, wherein the inorganic material comprises a metal oxide selected from silica, alumina, titania or zirconia.

Abstract: The invention provides superficially porous metal oxide or hybrid metal oxide monoliths with ordered pore structures. The superficially porous hybrid silica monoliths of the invention provide several major advantages over existing silica monoliths. When used in chromatography, the superficially porous hybrid silica monoliths of the invention deliver fast separation at very low back pressure and possess superb pH stability and much improved mechanical strength.

Abstract: The present invention is a process for making an inorganic/organic hybrid totally porous spherical silica particles by self assembly of surfactants that serve as organic templates via pseudomorphic transformation.

Abstract: Micelle-templated superficially porous particles having a solid core and an outer porous shell with ordered pore structures and a narrow particle size distribution, such as about ±5% (one sigma), and a high specific surface area of about 5 to about 1000 m2/g.

Abstract: The present invention is a process for making an inorganic/organic hybrid totally porous spherical silica particles by self assembly of surfactants that serve as organic templates via pseudomorphic transformation.

Abstract: Superficially porous hybrid particles include hybrid solid cores that each contain an inorganic material and an organic material; and porous hybrid outer shells each include the inorganic and organic materials and having ordered pores, wherein the ordered pores have a median pore size ranges from about 15 to about 1000 ? with a pore size distribution (one standard deviation) of no more than 50% of the median pore size and produce at least one X-ray diffraction peak between 0.01° and 10° of a 2? scan range; wherein the particles have a median size range from about 0.5 ?m to about 100 ?m with a particle size distribution (one standard deviation) of no more than 15% of the median particle size, wherein the inorganic material comprises a metal oxide selected from silica, alumina, titania or zirconia.

Abstract: A process for producing a chromatographic stationary phase for use in reversed-phase chromatography. Chromatographic stationary phases prepared according to the methods of the current invention and liquid chromatography columns, which include the stationary phases, are also provided.

Abstract: The present invention is a process for making an inorganic/organic hybrid totally porous spherical silica particles by self assembly of surfactants that serve as organic templates via pseudomorphic transformation.

Abstract: Micelle-templated superficially porous particles having a solid core and an outer porous shell with ordered pore structures and a narrow particle size distribution, such as about ±5% (one sigma), and a high specific surface area of about 5 to about 1000 m2/g.

Abstract: A process for producing a chromatographic stationary phase for use in reversed-phase chromatography. Chromatographic stationary phases prepared according to the methods of the current invention and liquid chromatography columns, which include the stationary phases, are also provided.

Abstract: A process for producing a chromatographic stationary phase for use in reversed-phase chromatography. Chromatographic stationary phases prepared according to the methods of the current invention and liquid chromatography columns, which include the stationary phases, are also provided.

Abstract: A process for producing a chromatographic stationary phase for use in reversed-phase chromatography. Chromatographic stationary phases prepared according to the methods of the current invention and liquid chromatography columns, which include the stationary phases, are also provided.

Abstract: The invention provides novel compositions, columns and methods for improved chromatographic separations. In particular, novel column packings are provided to improve overall chromatographic separation and efficiency. The invention provides a packing material having particles or mixtures of particles that are used for separation of small molecules, proteins or nucleic acids.

Abstract: An apparatus and method for filtering a liquid sample. A vessel defines a reservoir. An insert is at least partially and slidably positioned within the reservoir. The insert defines a collection volume, and the collection volume is in fluid communication with the reservoir. A separation element is positioned to partition the collection volume from the reservoir.

Abstract: A device adapted to hold and compress a granular medium is disclosed. The device includes a body having an opening. A channel is positioned in fluid communication with the opening. A flexible substrate is attached to the body overlying the channel. The substrate and the channel cooperate to form a conduit in fluid communication with the opening. A compression member is mounted on the body. The compression member is engageable with the substrate. Engagement of the substrate by the compression member compresses the granular medium within the conduit. A plug blocks the opening and retains the granular medium within the conduit.