Patents by Inventor William E. Briley

William E. Briley has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Quantification and spatio-temporal tracking of a target using a spherical nucleic acid (SNA)
    Patent number: 10301622
    Abstract: The present invention relates to methods of detecting and tracking a target molecule using a nanoparticle wherein the nanoparticle comprises a polynucleotide that can specifically associate with the target molecule, and wherein the association results in a change in a detectable marker that can be measured after association with the target molecule.
    Type: Grant
    Filed: November 4, 2014
    Date of Patent: May 28, 2019
    Assignee: NORTHWESTERN UNIVERSITY
    Inventors: Chad A. Mirkin, William E. Briley, Pratik S. Randeria, Nathaniel J. Kim
  • Biocompatible infinite coordination polymer nanoparticle-nucleic acid conjugates for antisense gene regulation
    Patent number: 9617541
    Abstract: Disclosed herein are metal-ligand complexes containing polynucleotides, compounds for making the same, and methods of using the same.
    Type: Grant
    Filed: August 20, 2015
    Date of Patent: April 11, 2017
    Assignee: NORTHWESTERN UNIVERSITY
    Inventors: Chad A. Mirkin, Colin Michael Calabrese, William E. Briley, Timothy J. Merkel
  • QUANTIFICATION AND SPATIO-TEMPORAL TRACKING OF A TARGET USING A SPHERICAL NUCLEIC ACID (SNA)
    Publication number: 20160281086
    Abstract: The present invention relates to methods of detecting and tracking a target molecule using a nanoparticle wherein the nanoparticle comprises a polynucleotide that can specifically associate with the target molecule, and wherein the association results in a change in a detectable marker that can be measured after association with the target molecule.
    Type: Application
    Filed: November 4, 2014
    Publication date: September 29, 2016
    Inventors: Chad A. MIRKIN, William E. BRILEY, Pratik S. RANDERIA, Nathaniel J. KIM
  • BIOCOMPATIBLE INFINITE COORDINATION POLYMER NANOPARTICLE -NUCLEIC ACID CONJUGATES FOR ANTISENSE GENE REGULATION
    Publication number: 20160053260
    Abstract: Disclosed herein are metal-ligand complexes containing polynucleotides, compounds for making the same, and methods of using the same.
    Type: Application
    Filed: August 20, 2015
    Publication date: February 25, 2016
    Inventors: Chad A. Mirkin, Colin Michael Calabrese, William E. Briley, Timothy J. Merkel