Abstract: Provided herein are methods for reducing or preventing surgery-associated hemolysis in subjects who have cold agglutinin disease (CAD) (e.g., been diagnosed with CAD or have had at least one symptom of CAD).

Abstract: Provided herein are methods for treating complement-mediated diseases and associated conditions.

Abstract: This invention relates to methods of treating sickle cell disease with VLA-4 antagonists and methods for evaluating the responsiveness of patients having sickle cell disease to treatment with VLA-4 antagonists.

Abstract: The invention provides an image motion compensation arrangement for enabling stabilization of the line of sight of a scanned imaging system mounted on a vehicle. In one example the scanned imaging system is a television camera assembly which is resiliently mounted and carries a plane mirror on to which is directed, via an auto-collimating lens, light from a light emitting diode. Light reflected by the plane mirror passes back through the auto-collimating lens to be received by a detector having quadrant receiving surfaces which resolve the complex motion of the camera assembly during movement of the vehicle into two orthogonal components defining the angular error caused by the motion in the sight line of the camera. The two orthogonal components are utilized to provide a pair of electrical signals utilizable to correct for the image motion resulting from the rotation of the sight line.