Patents by Inventor William E. Lowry

William E. Lowry has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Induced pluripotent stem cell derived glial enriched progenitor cells for the treatment of white matter stroke
    Patent number: 12544406
    Abstract: In various embodiments methods and compositions for improving a recovery of a subject after a cerebral ischemic injury, such as white matter stroke are provided. In certain embodiments, the methods involve administering human induced pluripotent glial enriched progenitor cells into the brain of the subject.
    Type: Grant
    Filed: September 27, 2016
    Date of Patent: February 10, 2026
    Assignee: The Regents of the University of California
    Inventors: Stanley Thomas Carmichael, Irene Lorenzo Llorente, William E. Lowry
  • COMPOSITIONS AND METHODS FOR MODULATING HAIR GROWTH
    Publication number: 20250304579
    Abstract: The present disclosure relates to compounds that are capable of inhibiting the mitochondrial pyruvate carrier and promoting hair growth. The disclosure further relates to methods of promoting hair growth or treating conditions or disorders affecting hair growth, such as baldness or alopecia.
    Type: Application
    Filed: February 14, 2025
    Publication date: October 2, 2025
    Inventors: William E. Lowry, Michael E. Jung, Heather R. Christofk, Xiaoguang Liu, Aimee Flores
  • Compositions and methods for modulating hair growth
    Patent number: 12227503
    Abstract: The present disclosure relates to compounds that are capable of inhibiting the mitochondrial pyruvate carrier and promoting hair growth. The disclosure further relates to methods of promoting hair growth or treating conditions or disorders affecting hair growth, such as baldness or alopecia.
    Type: Grant
    Filed: September 1, 2023
    Date of Patent: February 18, 2025
    Assignee: The Regents of the University of California
    Inventors: William E. Lowry, Michael E. Jung, Heather R. Christofk, Xiaoguang Liu, Aimee Flores
  • COMPOSITIONS AND METHODS FOR MODULATING HAIR GROWTH
    Publication number: 20240327400
    Abstract: The present disclosure relates to novel compounds that are capable of inhibiting the mitochondrial pyruvate carrier and promoting hair growth. The disclosure further relates to methods of promoting hair growth or treating conditions or disorders affecting hair growth, such as baldness or alopecia.
    Type: Application
    Filed: June 29, 2021
    Publication date: October 3, 2024
    Inventors: Daniel L. Sun, Michael E. Jung, Daniel Gil, William E. Lowry, Heather R. Christofk, Aimee Flores, Xiaoguang Liu
  • COMPOSITIONS AND METHODS FOR MODULATING HAIR GROWTH
    Publication number: 20240025895
    Abstract: The present disclosure relates to compounds that are capable of inhibiting the mitochondrial pyruvate carrier and promoting hair growth. The disclosure further relates to methods of promoting hair growth or treating conditions or disorders affecting hair growth, such as baldness or alopecia.
    Type: Application
    Filed: September 1, 2023
    Publication date: January 25, 2024
    Inventors: William E. Lowry, Michael E. Jung, Heather R. Christofk, Xiaoguang Liu, Aimee Flores
  • Compositions and methods for modulating hair growth
    Patent number: 11787804
    Abstract: The present disclosure relates to compounds that are capable of inhibiting the mitochondrial pyruvate carrier and promoting hair growth. The disclosure further relates to methods of promoting hair growth or treating conditions or disorders affecting hair growth, such as baldness or alopecia.
    Type: Grant
    Filed: June 23, 2022
    Date of Patent: October 17, 2023
    Assignee: The Regents of the University of California
    Inventors: William E. Lowry, Michael E. Jung, Heather R. Christofk, Xiaoguang Liu, Aimee Flores
  • COMPOSITIONS AND METHODS FOR MODULATING HAIR GROWTH
    Publication number: 20230114220
    Abstract: The present disclosure relates to compounds that are capable of inhibiting the mitochondrial pyruvate carrier and promoting hair growth. The disclosure further relates to methods of promoting hair growth or treating conditions or disorders affecting hair growth, such as baldness or alopecia.
    Type: Application
    Filed: June 23, 2022
    Publication date: April 13, 2023
    Inventors: William E. Lowry, Michael E. Jung, Heather R. Christofk, Xiaoguang Liu, Aimee Flores
  • Compositions and methods for modulating hair growth
    Patent number: 11472804
    Abstract: The present disclosure relates to compounds that are capable of inhibiting the mitochondrial pyruvate carrier and promoting hair growth. The disclosure further relates to methods of promoting hair growth or treating conditions or disorders affecting hair growth, such as baldness or alopecia.
    Type: Grant
    Filed: January 25, 2022
    Date of Patent: October 18, 2022
    Assignee: The Regents of the University of California
    Inventors: William E. Lowry, Michael E. Jung, Heather R. Christofk, Xiaoguang Liu, Aimee Flores
  • INDUCED PLURIPOTENT STEM CELL DERIVED GLIAL ENRICHED PROGENITOR CELLS FOR THE TREATMENT OF WHITE MATTER STROKE
    Publication number: 20220241345
    Abstract: In various embodiments methods and compositions for improving a recovery of a subject after a cerebral ischemic injury, such as white matter stroke are provided. In certain embodiments, the methods involve administering human induced pluripotent glial enriched progenitor cells into the brain of the subject.
    Type: Application
    Filed: February 17, 2022
    Publication date: August 4, 2022
    Applicant: The Regents of the University of California
    Inventors: Stanley Thomas Carmichael, Irene Lorenzo Llorente, William E. Lowry
  • COMPOSITIONS AND METHODS FOR MODULATING HAIR GROWTH
    Publication number: 20220153738
    Abstract: The present disclosure relates to compounds that are capable of inhibiting the mitochondrial pyruvate carrier and promoting hair growth. The disclosure further relates to methods of promoting hair growth or treating conditions or disorders affecting hair growth, such as baldness or alopecia.
    Type: Application
    Filed: January 25, 2022
    Publication date: May 19, 2022
    Inventors: William E. Lowry, Michael E. Jung, Heather R. Christofk, Xiaoguang Liu, Aimee Flores
  • Compositions and methods for modulating hair growth
    Patent number: 11312714
    Abstract: The present disclosure relates to compounds that are capable of inhibiting the mitochondrial pyruvate carrier and promoting hair growth. The disclosure further relates to methods of promoting hair growth or treating conditions or disorders affecting hair growth, such as baldness or alopecia.
    Type: Grant
    Filed: June 29, 2018
    Date of Patent: April 26, 2022
    Assignee: The Regents of the University of California
    Inventors: William E. Lowry, Michael E. Jung, Heather R. Christofk, Xiaoguang Liu, Aimee Flores
  • COMPOSITIONS AND METHODS FOR MODULATING HAIR GROWTH
    Publication number: 20220048908
    Abstract: The present disclosure relates to compounds that are capable of inhibiting the mitochondrial pyruvate carrier and promoting hair growth. The disclosure further relates to methods of promoting hair growth or treating conditions or disorders affecting hair growth, such as baldness or alopecia.
    Type: Application
    Filed: December 30, 2019
    Publication date: February 17, 2022
    Inventors: William E. Lowry, Michael E. Jung, Heather R. Christofk, Xiaoguang Liu, Aimee Flores
  • Compositions and methods for promoting hair growth with Mpc1 inhibitors
    Patent number: 11213513
    Abstract: Provided herein are methods of accelerating, promoting, or restoring hair growth, comprising administering to a subject in need thereof an effective amount of a compound of formula (I). Also provided are compositions comprising the compound of formula (I).
    Type: Grant
    Filed: August 25, 2017
    Date of Patent: January 4, 2022
    Assignee: The Regents of the University of California
    Inventors: William E. Lowry, Heather R. Christofk, Aimee Flores
  • COMPOSITIONS AND METHODS FOR MODULATING HAIR GROWTH
    Publication number: 20200253917
    Abstract: The present disclosure relates to pharmaceutical compositions containing electron transport chain (ETC) inhibitors, which are capable of promoting hair growth. The disclosure further relates to methods of promoting hair growth or treating conditions or disorders affecting hair growth, such as baldness or alopecia.
    Type: Application
    Filed: September 28, 2018
    Publication date: August 13, 2020
    Inventors: William E. Lowry, Heather R. Christofk, Matilde Miranda, Aimee Flores
  • COMPOSITIONS AND METHODS FOR MODULATING HAIR GROWTH
    Publication number: 20200157093
    Abstract: The present disclosure relates to compounds that are capable of inhibiting the mitochondrial pyruvate carrier and promoting hair growth. The disclosure further relates to methods of promoting hair growth or treating conditions or disorders affecting hair growth, such as baldness or alopecia.
    Type: Application
    Filed: June 29, 2018
    Publication date: May 21, 2020
    Inventors: William E. Lowry, Michael E. Jung, Heather R. Christofk, Xiaoguang Liu
  • COMPOSITIONS AND METHODS FOR PROMOTING HAIR GROWTH WITH MPC1 INHIBITORS
    Publication number: 20200030289
    Abstract: Provided herein are methods of accelerating, promoting, or restoring hair growth, comprising administering to a subject in need thereof an effective amount of a compound of formula (I). Also provided are compositions comprising the compound of formula (I).
    Type: Application
    Filed: August 25, 2017
    Publication date: January 30, 2020
    Inventors: William E. Lowry, Heather R. Christofk
  • COMPOSITIONS AND METHODS FOR MODULATING HAIR GROWTH
    Publication number: 20190350909
    Abstract: The present disclosure relates to pharmaceutical compositions and methods for inhibiting Pde, promoting hair growth, and treating hair growth disorders, such as baldness or alopecia.
    Type: Application
    Filed: May 17, 2019
    Publication date: November 21, 2019
    Inventors: William E. Lowry, Matilde Miranda
  • INDUCED PLURIPOTENT STEM CELL DERIVED GLIAL ENRICHED PROGENITOR CELLS FOR THE TREATMENT OF WHITE MATTER STROKE
    Publication number: 20180271911
    Abstract: In various embodiments methods and compositions for improving a recovery of a subject after a cerebral ischemic injury, such as white matter stroke are provided. In certain embodiments, the methods involve administering human induced pluripotent glial enriched progenitor cells into the brain of the subject.
    Type: Application
    Filed: September 27, 2016
    Publication date: September 27, 2018
    Applicant: The Regents of the University of California
    Inventors: Stanley Thomas Carmichael, Irene Lorenzo Llorente, William E. Lowry
  • Generation of pluripotent cells from fibroblasts
    Patent number: 9005966
    Abstract: Provided are methods and compositions useful for producing and propagating stem cells from fibroblasts.
    Type: Grant
    Filed: November 19, 2008
    Date of Patent: April 14, 2015
    Assignee: The Regents of the University of California
    Inventors: William E. Lowry, Kathrin Plath
  • GENERATION OF PLURIPOTENT CELLS FROM FIBROBLASTS
    Publication number: 20100285589
    Abstract: Provided are methods and compositions useful for producing and propagating stem cells from fibroblasts.
    Type: Application
    Filed: November 19, 2008
    Publication date: November 11, 2010
    Applicant: THE REGENTS OF THE UNIVERSITY OF CALIFORNIA
    Inventors: William E. Lowry, Kathrin Plath