Abstract: An apparatus for multimodal imaging of an object includes a support stage for receiving an object to be imaged; an object supported on the stage, a light source for producing a beam to illuminate the object; a filter positioned to receive and pass the beam toward the object; and a lens and camera system for capturing an image of the object. The apparatus may include a tiltable filter for filtering light from the source.

Abstract: An apparatus for multimodal imaging of an object includes a support stage for receiving an object to be imaged; an object supported on the stage, the object having been treated with a biocompatible imaging probe comprising nanoparticles carrying one or more targeting moieties and one or more diagnostic components for enabling capture of images of the object; a light source for producing a beam to illuminate the object; a filter positioned to receive and pass the beam toward the object; and a lens and camera system for capturing an image of the object. The apparatus may include a tiltable filter for filtering light from the source.

Abstract: A method and apparatus are disclosed for measuring long bone density of small animals. A phosphor screen or plate is provided of a type that transduces incident ionizing radiation to emitted light. A small animal is positioned before the phosphor screen or plate and exposed to soft X-radiation having an energy level in the range of 11 to 16 Kev. Light emitted by the phosphor screen or plate is captured using a digital camera and a digital X-ray image is prepared of a long bone of the animal. The X-ray image is transformed into an X-ray density image and a region of interest is defined on the long bone in the X-ray density image. At least one row of pixels is scanned within the region of interest of the X-ray density image. A nonlinear least squares analysis of data obtained from the scanning step is conducted using a cylindrical model for the long bone within the region of interest.

Abstract: A combination of nanoparticles is disclosed comprised of amine functionalized polyethylene glycol in which one particle with a fluorescent donor dye having one wavelength excitation maximum and at least one additional particle with a second fluorescent dye having a second, higher wavelength excitation maximum, the particles having the same or different biomolecule targeting moieties bound to their external surfaces.

Abstract: An item that might be lost is provided with a badge featuring an array of glass beads. In seeking to retrieve such a lost item, an atmospheric-penetrating beam of laser is directed into the search area, and the signals from a reflectometer are monitored. The item having the badge of the array of glass beads is more easily retrievable when lost or mislaid than an item without such badge.

Abstract: An imaging system including: a lens; a dichroic filter positioned in front of the lens; and a high pass filter positioned between the lens and the dichroic filter. An appropriate design coordinating the components of such an imaging system diminishes imaging artifacts related to wide-angle imaging of fluorescent objects.

Abstract: An ordinary golf ball is cleaned and then treated with an emulsion depositing in the dimples a hologram having the capacity to reflect a pre-selected wavelength of laser-beam. If a player temporarily looses such ball, a hand-held unit directs an infra-red laser beam of said pre-selected wavelength, desirably one not absorbed by atmospheric moisture, such as 1310 nm. Said hand-held unit contains an analyzer evaluating the light reflected back to such analyzer and attributable to such laser beam of said pre-selected wave-length. By evaluating the intensity of such reflected light, the golfer can target the location of the temporarily lost ball. Upon approaching the lost ball the angle at which the unit would be held would be modified for focusing on the lost ball. Earphones, meters, or other diagnostic equipment can monitor the intensity of the light reflected back from such laser beam.

Abstract: An ordinary golf ball is cleaned and then heated with an emulsion depositing in the dimples a hologram having the capacity to reflect a pre-selected wavelength of laser-beam. If a player temporarily losses such ball, a hand-held unit directs an infra-red laser beam of said pre-selected wavelength, desirably one not absorbed by atmospheric moisture, such as 1310 nm. Said hand-held unit contains an analyzer evaluating the light reflected back to such analyzer and attributable to such laser bean of said pre-selected wave-length. By evaluating the intensity of such reflected light, the golfer can target the location of the temporarily lost ball. Upon approaching the lost ball the angle at which the unit would be held would be modified for focusing on the lost ball. Earphones, meters, or other diagnostic equipment can monitor the intensity of the light reflected back from such laser beam.

Abstract: An imaging system with an imaging assemblage including a prompt phosphor layer for converting an ionizing radiation image into a light image, and a transparent layer supporting the phosphor layer; wherein the light image is transmitted through the transparent layer; an electronic camera for converting the light image into an electronic image; and a light image transmission system between the imaging assemblage and the electronic camera for transmitting the light image to the electronic camera.