Patents by Inventor William F. McCoy

William F. McCoy has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Publication number: 20240132930
    Abstract: To determine the presence of Mycobacterium in an environment, a sample from the environment can be plated onto a growth medium that is selective for Mycobacterium. Prior to plating, the sample may be treated with a compound containing sodium dodecyl sulfate containing glycine hydrochloride. Plating may occur immediately after the addition of the compound or after a standing period. The agar based growth medium can include a high concentration of crystal violet, in excess of 0.5 ?g/ml. Mycobacterium colonies will generally appear white while other colonies will generally appear stained purple or another color.
    Type: Application
    Filed: November 13, 2023
    Publication date: April 25, 2024
    Inventors: Leah Wickenberg, Avneet K. Chhabra, William F. McCoy
  • Patent number: 11814668
    Abstract: To determine the presence of Mycobacterium in an environment, a sample from the environment can be plated onto a growth medium that is selective for Mycobacterium. The agar based growth medium can include a high concentration of crystal violet, in excess of 0.5 ?g/ml. The process may be made further selective for Mycobacterium by treating the sample with sodium dodecyl sulfate containing glycine hydrochloride for at least 4 minutes at room temperature, prior to plating. Mycobacterium colonies will generally appear white while other colonies will generally appear stained purple or another color.
    Type: Grant
    Filed: February 10, 2021
    Date of Patent: November 14, 2023
    Assignee: Phigenics, LLC
    Inventors: Leah Wickenberg, Avneet K. Chhabra, Katherine E. Fisher, William F. McCoy
  • Publication number: 20220145371
    Abstract: A process for detecting viable waterborne pathogens in a water sample, includes enriching at least a portion of the sample with an enrichment broth and taking a first DNA extract at time T0 and a second DNA extract at time T2 after an incubation period. Real-time polymerase chain reaction performed on the DNA extracts yields respective cycle threshold values Ct. The change in Ct provides an indication of viability of the targeted pathogen in the sample. An order of magnitude quantification of the sample can also be performed using a serial dilution technique on the T0 DNA extract. The process has particular application for detecting Legionella, including viable but not culturable cells.
    Type: Application
    Filed: November 2, 2021
    Publication date: May 12, 2022
    Inventors: Leah Wickenberg, Katherine Fisher, William F. McCoy
  • Publication number: 20210254124
    Abstract: To determine the presence of Mycobacterium in an environment, a sample from the environment can be plated onto a growth medium that is selective for Mycobacterium. The agar based growth medium can include a high concentration of crystal violet, in excess of 0.5 ?g/ml. The process may be made further selective for Mycobacterium by treating the sample with sodium dodecyl sulfate containing glycine hydrochloride for at least 4 minutes at room temperature, prior to plating. Mycobacterium colonies will generally appear white while other colonies will generally appear stained purple or another color.
    Type: Application
    Filed: February 10, 2021
    Publication date: August 19, 2021
    Inventors: Leah Wickenberg, Avneet K. Chhabra, Katherine E. Fisher, William F. McCoy
  • Publication number: 20200208200
    Abstract: A process for detecting viable waterborne pathogens in a water sample, includes enriching a concentrate of bacteria from the sample and taking a first DNA extract at time T0 and a second DNA extract at time T2 after an incubation period. Real-time polymerase chain reaction performed on the DNA extracts yields respective cycle threshold values Ct. The change in Ct provides an indication of the targeted pathogen in the sample. An order of magnitude quantification of the sample can also be performed using a serial dilution technique on the T0 DNA extract. The process has particular application for detecting Legionella, including viable but not culturable cells.
    Type: Application
    Filed: December 29, 2019
    Publication date: July 2, 2020
    Inventors: Leah Wickenberg, Katherine Fisher, William F. McCoy
  • Patent number: 7939314
    Abstract: Methods and compositions detect and quantify viable Legionella. Dip-slides that include an absorbent medium, growth promoting, and growth selective substances are useful in rapid detection and quantification of microcolonies of Legionella. Most probable number method of detection and quantification of Legionella are disclosed.
    Type: Grant
    Filed: November 25, 2008
    Date of Patent: May 10, 2011
    Assignee: Phigenics, LLC
    Inventor: William F. McCoy
  • Patent number: 7935521
    Abstract: Methods and compositions detect and quantify viable Legionella. Dip-slides that include an absorbent medium, growth promoting, and growth selective substances are useful in rapid detection and quantification of microcolonies of Legionella. Most probable number method of detection and quantification of Legionella are disclosed.
    Type: Grant
    Filed: March 15, 2006
    Date of Patent: May 3, 2011
    Assignee: Phigenics, LLC
    Inventor: William F. McCoy
  • Patent number: 7901932
    Abstract: Methods and compositions detect and quantify viable Legionella and other heterotrophic aerobic bacteria. Dip-slides that include an absorbent medium, growth promoting, and growth selective substances are useful in rapid detection and quantification of microcolonies of Legionella. Most probable number method of detection and quantification of Legionella are disclosed.
    Type: Grant
    Filed: March 15, 2007
    Date of Patent: March 8, 2011
    Assignee: Phigenics, LLC
    Inventor: William F. McCoy
  • Publication number: 20090087902
    Abstract: Methods and compositions detect and quantify viable Legionella. Dip-slides that include an absorbent medium, growth promoting, and growth selective substances are useful in rapid detection and quantification of microcolonies of Legionella. Most probable number method of detection and quantification of Legionella are disclosed.
    Type: Application
    Filed: November 25, 2008
    Publication date: April 2, 2009
    Applicant: Phigenics LLC
    Inventor: William F. McCoy
  • Patent number: 6423267
    Abstract: Stable biocide formulations containing oxidizing bromine are provided for biofouling control in industrial water systems. The formulations contain at least one stable oxidizing bromine compound that is prepared from at least one oxidizing chemical reagent, at least one bromine source and at least one bromine or halogen stabilizer. The resulting products are a mixture of stable oxidizing bromine compounds that can be used as a biocide in an industrial water system.
    Type: Grant
    Filed: March 2, 2000
    Date of Patent: July 23, 2002
    Assignee: Nalco Chemical Company
    Inventors: Shunong Yang, William F. McCoy, Anthony W. Dallmier
  • Patent number: 6419879
    Abstract: A synergistic composition and method for controlling biological growth in industrial fluids are disclosed, wherein the composition comprises stabilized sodium hypobromite and at least one compound selected from the group consisting of coco alkyldimethylamine oxide, n-coco alkyltrimethylenediamine, tetra-alkyl phosphonium chloride, 7-oxabicyclo[2.2.1]heptane-2,3-dicarboxylic acid and 4,5-dichloro-2-n-octyl-4-isothiazoline-3-one.
    Type: Grant
    Filed: August 12, 1999
    Date of Patent: July 16, 2002
    Assignee: Nalco Chemical Company
    Inventors: Andrew J. Cooper, Anthony W. Dallmier, Robert F. Kelly, William F. McCoy, Xi Ma
  • Patent number: 6322749
    Abstract: A synergistic composition and method for inhibiting microbiological growth which comprises a combination of stabilized sodium hypobromite with a mixture of 5-chloro-2-methyl 4-isothiazolin-3-one and 2-methyl-4-isothiazolin-3-one.
    Type: Grant
    Filed: February 24, 1999
    Date of Patent: November 27, 2001
    Assignee: Nalco Chemical Company
    Inventors: Robert E. McCarthy, Anthony W. Dallmier, William F. McCoy
  • Patent number: 6287473
    Abstract: Stable oxidizing bromine compounds are prepared by preparing a caustic solution comprising a halogen stabilizer, water and an alkali or alkaline earth metal hydroxide, the halogen stabilizer being selected from the group consisting of R—NH2, R—NH—R1, R—SO2—NH2, R—SO2—NHR1, R—CO—NH2, R—CO—NH—R1 and R—CO—NH—CO—R1 wherein R is a hydroxy group, an alkyl group or an aromatic group and R1 is an alkyl group or an aromatic group, adding bromine chloride to the solution while mixing the solution, and cooling the solution.
    Type: Grant
    Filed: March 3, 2000
    Date of Patent: September 11, 2001
    Assignee: Nalco Chemical Company
    Inventors: Shunong Yang, William F. McCoy, Anthony W. Dallmier
  • Patent number: 6270722
    Abstract: Stabilized bromine solutions are prepared by combining a bromine source and a stabilizer to form a mixture, adding an oxidizer to the mixture, and then adding, an alkaline source to adjust the pH of the mixture to at least 13.
    Type: Grant
    Filed: March 31, 1999
    Date of Patent: August 7, 2001
    Assignee: Nalco Chemical Company
    Inventors: Shunong Yang, William F. McCoy, Eric J. Allain, Eric R. Myers, Anthony W. Dallmier
  • Patent number: 6156229
    Abstract: Stable biocide formulations containing oxidizing bromine are provided for biofouling control in industrial water systems. The formulations contain at least one stable oxidizing bromine compound that is prepared from at least one oxidizing chemical reagent, at least one bromine source and at least one bromine or halogen stabilizer. The resulting products are a mixture of stable oxidizing bromine compounds that can be used as a biocide in an industrial water system.
    Type: Grant
    Filed: June 29, 1998
    Date of Patent: December 5, 2000
    Assignee: Nalco Chemical Company
    Inventors: Shunong Yang, William F. McCoy, Anthony W. Dallmier
  • Patent number: 6136205
    Abstract: The invention is a method for preparing a stabilized aqueous alkali or alkaline earth metal hypobromite solution. The method comprises the steps of:a. Mixing an aqueous solution of alkali or alkaline earth metal hypochlorite having from about 5 percent to about 70 percent available halogen as chlorine with a water soluble bromide ion source;b. Allowing the bromide ion source and the alkali or alkaline earth metal hypochlorite to react to form a 0.5 to 70 percent by weight aqueous solution of unstabilized alkali or alkaline earth metal hypobromite;c. Adding to the unstabilized solution of alkali or alkaline earth metal hypobromite an aqueous solution of an alkali metal sulfamate in a quantity to provide a molar ratio of alkali metal sulfamate to alkali or alkaline earth metal hypobromite is from about 0.5 to about 7; and,d. Recovering a stabilized aqueous alkali or alkaline earth metal hypobromite solution.
    Type: Grant
    Filed: May 5, 1999
    Date of Patent: October 24, 2000
    Assignee: Nalco Chemical Company
    Inventors: Anthony W. Dallmier, William F. McCoy, Shunong Yang
  • Patent number: 6123870
    Abstract: Stable oxidizing bromine compounds are prepared by preparing a caustic solution comprising a halogen stabilizer, water and an alkali or alkaline earth metal hydroxide, the halogen stabilizer being selected from the group consisting of R--NH.sub.2, R--NH--R.sup.1, R--SO.sub.2 --NH.sub.2, R--SO.sub.2 --NHR.sup.1, R--CO--NH.sub.2, R--CO--NH--R.sup.1 and R--CO--NH--CO--R.sup.1 wherein R is a hydroxy group, an alkyl group or an aromatic group and R.sup.1 is an alkyl group or an aromatic group, adding bromine chloride to the solution while mixing the solution, and cooling the solution.
    Type: Grant
    Filed: April 21, 1999
    Date of Patent: September 26, 2000
    Assignee: Nalco Chemical Company
    Inventors: Shunong Yang, William F. McCoy, Anthony W. Dallmier
  • Patent number: 6096225
    Abstract: A method is disclosed for controlling biofouling in an aqueous medium by treating the aqueous medium with an oil-in-water emulsion comprising an antimicrobial oil phase and at least one emulsifier. This method efficiently controls biofouling in the aqueous medium by specifically targeting the antimicrobial oil phase directly to biofilms, cell surfaces and cell aggregates in a concentrated form.
    Type: Grant
    Filed: September 11, 1998
    Date of Patent: August 1, 2000
    Assignee: Nalco Chemical Company
    Inventors: Shunong Yang, Michael V. Enzien, May M. Wu, William F. McCoy
  • Patent number: 6017459
    Abstract: An in-line apparatus for monitoring membrane deposition is provided having an exterior body that defines an interior compartment for receiving a fluid stream. A coupon rack is positioned in the interior compartment and suspends at least one coupon holder. The coupon holder holds at least one membrane for collection of deposition present within a filtration system. The apparatus allows examination of membrane surface deposition without sacrificing a membrane element and also provides timely diagnostic information on a filtration system. The present invention also provides a method of monitoring membrane deposition as well as a filtration system incorporating an in-line apparatus for monitoring membrane deposition.
    Type: Grant
    Filed: March 8, 1993
    Date of Patent: January 25, 2000
    Assignee: Nalco Chemical Company
    Inventors: E. H. Kelle Zeiher, Brian F. Post, William F. McCoy, Timothy L. Chaffin
  • Patent number: 6007726
    Abstract: Stable oxidizing biocide formulations containing bromine are provided for biofouling control in industrial water systems. The formulations contain at least one stable oxidizing bromine compound that is prepared from at least one oxidizing chemical reagent, at least one bromine source and at least one bromine or halogen stabilizer. The resulting products are a mixture of stable oxidizing bromine compounds that can be used as a primary or secondary biocide in an industrial water system.
    Type: Grant
    Filed: April 29, 1998
    Date of Patent: December 28, 1999
    Assignee: Nalco Chemical Company
    Inventors: Shunong Yang, William F. McCoy