Abstract: An object processing system including at least one automated mobile shuttle is disclosed that includes a mobile chassis unit for moving the automated mobile shuttle in a first direction, a payload for supporting at least one object thereon, said payload including a plurality of tines, and a payload translation system for translating the payload toward a receiving surface in at least a second direction that is orthogonal with respect to the first direction, the payload translation system providing that the plurality of tines are adapted to engage recessed areas within the receiving surface.

Abstract: An end-effector system is disclosed for use with a programmable motion device. The end-effector system includes an arm attachment portion for attachment to an arm of the programmable motion device, an end-effector attachment portion for attachment to an end-effector for grasping objects, a rotational shaft portion for rotational attachment to the arm attachment portion, said rotational shaft portion being coupled to the end-effector attachment portion at a distal end thereof, and a motor system providing rotation of the rotational shaft portion as well as the end-effector attachment portion with respect to the arm attachment portion.

Abstract: A method is disclosed of changing a tool on a programmable motion device. The method includes the steps of moving an attachment portion of an end effector of the programmable motion device in a continuous motion; while the attachment portion of the end effector moves in the continuous motion, engaging one of: the attachment portion of the end effector with the tool, or the tool attached to the attachment portion of the end effector with an exchange system, and continuing to move the attachment portion of the end effector in the continuous motion to change a connection status of the attachment portion of the end effector while the attachment portion of the end effector moves in the continuous motion.

Abstract: A method is disclosed of changing a tool on a programmable motion device. The method includes the steps of moving an attachment portion of an end effector of the programmable motion device in a continuous motion; while the attachment portion of the end effector moves in the continuous motion, engaging one of: the attachment portion of the end effector with the tool, or the tool attached to the attachment portion of the end effector with an exchange system, and continuing to move the attachment portion of the end effector in the continuous motion to change a connection status of the attachment portion of the end effector while the attachment portion of the end effector moves in the continuous motion.

Abstract: An object processing system is disclosed that includes a mobile system for moving from a proximal base toward a plurality of objects to be processed, and a programmable motion device supported on the mobile unit at a proximal end of the programmable motion device, the programmable motion device including an end-effector at a distal end thereof, the end-effector including a first stationary portion that remains stationary with respect to the distal end of the programmable motion device, and a second movable portion that moves with respect to the first stationary portion, the second movable portion for contacting at least one object of the plurality of objects for urging the at least one object from the plurality of objects toward the mobile system.

Abstract: An object processing system is disclosed that includes a vertical structure extending in a vertical direction and at least one automated mobile carrier adapted for movement with respect to the vertical structure. The at least one automated mobile carrier includes a carrier base portion including at least two wheels for moving the automated mobile carrier in at least one direction that is generally orthogonal with respect to the vertical direction, a carrier upper portion for receiving at least one object thereon to be moved by the automated mobile carrier, and an elevation system for lifting the carrier upper portion of the automated mobile carrier with respect to the carrier base portion of the automated mobile carrier such that an engagement system of the carrier upper portion engages the vertical structure.

Abstract: An object processing system is disclosed that includes a object processing system including at least one automated mobile carrier including a carrier base portion including at least two wheels for moving the automated mobile carrier in at least one horizontal direction, a carrier upper portion that includes a payload receiving portion for receiving at least one object thereon to be moved by the automated mobile carrier, and an extension system for extending the payload receiving portion horizontally away from and toward a central region of the automated mobile carrier, and an elevation system for elevating the carrier upper portion including the payload receiving portion with respect to the carrier base portion independently of the extension system.

Abstract: A method is disclosed of changing a tool on a programmable motion device. The method includes the steps of moving an attachment portion of an end effector of the programmable motion device in a continuous motion; while the attachment portion of the end effector moves in the continuous motion, engaging one of: the attachment portion of the end effector with the tool, or the tool attached to the attachment portion of the end effector with an exchange system, and continuing to move the attachment portion of the end effector in the continuous motion to change a connection status of the attachment portion of the end effector while the attachment portion of the end effector moves in the continuous motion.

Abstract: Provided herein, in some embodiments, are compositions and methods for a plasmid addiction system based on essential glycolytic genes. Also provided herein, in some embodiments, are compositions and methods for a plasmid addiction system based on an outer membrane efflux protein.

Abstract: An object processing system including at least one automated mobile shuttle is disclosed that includes a mobile chassis unit for moving the automated mobile shuttle in a first direction, a payload for supporting at least one object thereon, said payload including a plurality of tines, and a payload translation system for translating the payload toward a receiving surface in at least a second direction that is orthogonal with respect to the first direction, the payload translation system providing that the plurality of tines are adapted to engage recessed areas within the receiving surface.

Abstract: An object processing system is disclosed that includes an automated mobile shuttle including a mobile chassis for moving the automated mobile shuttle in a first direction, a payload for supporting at least one object thereon, the payload including a plurality of tines, and a payload translation system, and an automated mobile carrier movable in a second direction that is generally orthogonal with respect to the first direction, the automated mobile carrier including a receiving surface for receiving the plurality of tines of the payload, wherein the payload translation system of the automated mobile shuttle is for translating the payload toward the receiving surface of the automated mobile carrier, and the payload translation system provides that the plurality of tines are adapted to engage recessed areas within the receiving surface of the automated mobile carrier.

Abstract: A method is disclosed of changing a tool on a programmable motion device. The method includes the steps of moving an attachment portion of an end effector of the programmable motion device in a continuous motion; while the attachment portion of the end effector moves in the continuous motion, engaging one of: the attachment portion of the end effector with the tool, or the tool attached to the attachment portion of the end effector with an exchange system, and continuing to move the attachment portion of the end effector in the continuous motion to change a connection status of the attachment portion of the end effector while the attachment portion of the end effector moves in the continuous motion.

Abstract: In one aspect, an autonomous cleaning robot includes a drive configured to propel the robot along the floor surface and a tank assembly. The tank assembly includes a reservoir, left and right receptacles, and a handle extending across a cover of the tank assembly, the handle being moveable between a first position and a second position, wherein when the handle is in the second position, the tank assembly is locked in position. The tank assembly also includes left and right latch assemblies receivable by the left and right receptacles, respectively. Each latch assembly includes a moveable assembly configured to lock the tank assembly in position when the handle is in the second position.

Abstract: An end-effector system is disclosed for use with a programmable motion device. The end-effector system includes an arm attachment portion for attachment to an arm of the programmable motion device, an end-effector attachment portion for attachment to an end-effector for grasping objects, a rotational shaft portion for rotational attachment to the arm attachment portion, said rotational shaft portion being coupled to the end-effector attachment portion at a distal end thereof, and a motor system providing rotation of the rotational shaft portion as well as the end-effector attachment portion with respect to the arm attachment portion.

Abstract: Provided herein, in some aspects, are compositions of nucleic acids comprising an initial transcribed sequence and unique nucleic acid designs for high-yield and cost-effective production of ribonucleic acids.

Abstract: In the various aspects and embodiments, this disclosure provides messenger RNA (mRNA) constructs for therapeutic delivery, as well as methods for making such mRNA constructs and pharmaceutical compositions comprising the same (including mRNA vaccine compositions). In still other aspects, the invention provides methods for treating patients by expression of therapeutic proteins, including for preventing or reducing probability of infection by, or illness involving, a virus. Exemplary viruses include coronaviruses (such as SARS-CoV-2 and variants therefore) and influenza viruses, among others.

Abstract: This document describes a mobile cleaning robot that includes a chassis that supports a drive system, a debris collection volume; and a cleaning head formed to complete a bottom of the robot. The cleaning head includes a frame for affixing the cleaning head to the chassis, a monolithic housing having an interior cavity, a suspension linkage movably suspending the monolithic housing from the frame, the suspension linkage being configured to lift the monolithic housing, a diaphragm formed of a flexible material and mated to the monolithic housing, a rigid duct mated the frame to form a pneumatic path between the monolithic housing and the rigid duct through the diaphragm, and cleaning extractors disposed in the interior cavity of the monolithic housing.

Abstract: In one aspect, an autonomous cleaning robot includes a drive configured to propel the robot along the floor surface and a tank assembly. The tank assembly includes a reservoir, left and right receptacles, and a handle extending across a cover of the tank assembly, the handle being moveable between a first position and a second position, wherein when the handle is in the second position, the tank assembly is locked in position. The tank assembly also includes left and right latch assemblies receivable by the left and right receptacles, respectively. Each latch assembly includes a moveable assembly configured to lock the tank assembly in position when the handle is in the second position.

Abstract: In one aspect, an autonomous cleaning robot includes a drive configured to propel the robot along the floor surface and a tank assembly. The tank assembly includes a reservoir, left and right receptacles, and a handle extending across a cover of the tank assembly, the handle being moveable between a first position and a second position, wherein when the handle is in the second position, the tank assembly is locked in position. The tank assembly also includes left and right latch assemblies receivable by the left and right receptacles, respectively. Each latch assembly includes a moveable assembly configured to lock the tank assembly in position when the handle is in the second position.

Abstract: A radar detection system and method include a radar detector for transmitting radar signals over a plurality of sweeps, detecting reflected returning radar signals for the sweeps, and converting the reflected returning radar signals into digital data signals, which are processed to by a time-averaging approach by which data for each of a plurality of range-plus-velocity (RV) bins is analyzed over multiple sweeps to detect a first clutter object at particular RV value and an RV-averaging approach by which data for a plurality of RV values within each sweep are combined to form RV averages for each sweep and the RV averages for a plurality of sweeps are analyzed over multiple sweeps to detect a second clutter object. The processor indicates that the radar detector is not blocked if the time-averaging approach or the RV averaging approach results in at least one of the clutter objects being detected.