Patents by Inventor William Fobare

William Fobare has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Amino-5-[4-(difluoromehtoxy)phenyl]-5-phenylimidazolone compounds for the inhibition of beta-secretase
    Publication number: 20070072925
    Abstract: The present invention provides a 2-amino-5-[4-(difluoromethoxy)phenyl]-5-phenylimidazolone compound of formula I The present invention also provides methods for the use thereof to inhibit ?-secretase (BACE) and treat ?-amyloid deposits and neurofibrillary tangles.
    Type: Application
    Filed: September 25, 2006
    Publication date: March 29, 2007
    Applicant: Wyeth
    Inventors: Michael Malamas, James Erdei, William Fobare, Dominick Quagliato, Schuyler Antane, Albert Robichaud
  • Amino-5-(5-membered)hetero-arylimidazolone compounds and the use thereof for beta-secretase modulation
    Publication number: 20070004786
    Abstract: The present invention provides a 2-amino-5-heteroaryl-5-phenylimidazolone compound of formula I The present invention also provides methods for the use thereof to inhibit ?-secretase (BACE) and treat ?-amyloid deposits and neurofibrillary tangles
    Type: Application
    Filed: June 29, 2006
    Publication date: January 4, 2007
    Applicant: Wyeth
    Inventors: Michael Malamas, Ping Zhou, William Fobare, William Solvibile, Iwan Gunawan, James Erdei, Yinfa Yan, Patrick Andrae, Dominick Quagliato
  • Substituted thienyl and furyl acylguanidines and methods of their use as beta-secretase modulators
    Publication number: 20060183792
    Abstract: The present invention provides a substituted thienyl or furyl acylguanidine compound of formula I The present invention also provides methods for the inhibition of ?-secretase (BACE) and for the treatment of ?-amyloid deposits and neurofibrillary tangles.
    Type: Application
    Filed: February 13, 2006
    Publication date: August 17, 2006
    Applicant: Wyeth
    Inventors: William Fobare, William Solvibile
  • Amino-pyridines as inhibitors of beta-secretase
    Publication number: 20060173049
    Abstract: The present invention provides an amino-pyridine compound of formula I The present invention also provides methods for the use thereof to inhibit ?-secretase (BACE) and treat ?-amyloid deposits and neurofibrillary tangles.
    Type: Application
    Filed: January 31, 2006
    Publication date: August 3, 2006
    Applicant: Wyeth
    Inventors: Michael Malamas, William Fobare, William Solvibile, Frank Lovering, Jeffrey Condon, Albert Robichaud
  • Thienoisoquinoline-phenylsulfonamides and their use as ER-NFkappaB inhibitors
    Publication number: 20060154875
    Abstract: This invention provides estrogen receptor modulators having the structure: wherein R1 to R7 are as defined in the specification; or a pharmaceutically acceptable salt thereof.
    Type: Application
    Filed: December 20, 2005
    Publication date: July 13, 2006
    Applicant: Wyeth
    Inventors: Richard Coghlan, William Fobare, Eugene Trybulski