Patents by Inventor William Frank Greenlee

William Frank Greenlee has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Tumor-specific P450 protein
    Publication number: 20030087408
    Abstract: The discovery that CYP1B1 protein is detectable in a wide range of human cancers of different histogenetic types, but is not detectable in non-cancerous tissues, gives rise to diagnostic methods for detecting tumors based on this protein as a marker, and to the possibility of tumor therapies involving the protein. A diagnostic method may include the steps of (a) obtaining from a patient a tissue sample to be tested for the presence of cancer cells; (b) producing a prepared sample in a sample preparation process; (c) contacting the prepared sample with an antibody that reacts with human CYP1B1 protein; and (d) detecting binding of the antibody to CYP1B1 protein in the prepared sample.
    Type: Application
    Filed: September 23, 2002
    Publication date: May 8, 2003
    Applicant: University of Aberdeen, a Scotland corporation
    Inventors: William Thomas Melvin, Graeme Ian Murray, Michael Danny Burke, William Frank Greenlee
  • Tumour-specific P450 protein
    Publication number: 20020052013
    Abstract: The discovery that CYP1B1 protein is detectable in a wide range of human cancers of different histogenetic types, but is not detectable in non-cancerous tissues, gives rise to diagnostic methods for detecting tumors based on this protein as a marker, and to the possibility of tumor therapies involving the protein. A diagnostic method may include the steps of: (a) obtaining from a patient a tissue sample to be tested for the presence of cancer cells; (b) producing a prepared sample in a sample preparation process; (c) contacting the prepared sample with an antibody that reacts with human CYP1B1 protein; and (d) detecting binding of the antibody to CYP1B1 protein in the prepared sample.
    Type: Application
    Filed: June 4, 2001
    Publication date: May 2, 2002
    Inventors: William Thomas Melvin, Graeme Ian Murray, Michael Danny Burke, William Frank Greenlee
  • Tumor-specific P450 protein
    Patent number: 6242203
    Abstract: The discovery that Cyp1B1 protein is detectable in a wide range of human cancers of different histogenetic types, but is not detectable in non-cancerous tissues, gives rise to diagnostic methods for detecting tumors based on this protein as a marker, and to the possibility of tumor therapies involving the protein. A diagnostic method may include the steps of: (a) obtaining from a patient a tissue sample to be tested for the presence of cancer cells; (b) producing a prepared sample in a sample preparation process; (c) contacting the prepared sample with an antibody that reacts with human Cyp1B1 protein; and (d) detecting binding of the antibody to CYP1B1 protein in the prepared sample.
    Type: Grant
    Filed: January 22, 1999
    Date of Patent: June 5, 2001
    Assignees: University of Aberdeen, University of Massachusetts
    Inventors: William Thomas Melvin, Graeme Ian Murray, Michael Danny Burke, William Frank Greenlee